Tagetitoxin inhibits RNA polymerase through trapping of the trigger loop (Q24596371)

6

object named as

Evgeny Nudler

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author name string

Vladimir Svetlov

2

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Sondra Maureen Nemetski

3

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Vitaly Epshtein

4

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Timothy Cardozo

Journal of Biological Chemistry

5

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language of work or name

English

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publication date

18 November 2011

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published in

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volume

286

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issue

46

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page(s)

40395-400

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cites work

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The RNA polymerase II trigger loop functions in substrate selection and is directly targeted by alpha-amanitin

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Structural basis for transcription inhibition by tagetitoxin

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Mechanistic aspects of tagetitoxin inhibition of RNA polymerase from Escherichia coli

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Controlled interplay between trigger loop and Gre factor in the RNA polymerase active centre

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Tagetitoxin inhibits RNA synthesis directed by RNA polymerases from chloroplasts and Escherichia coli

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30 May 2018

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21 January 2018

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A Ratchet Mechanism of Transcription Elongation and Its Control

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21 January 2018

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Mutations of the beta subunit of RNA polymerase alter both transcription pausing and transcription termination in the trp operon leader region in vitro

28 November 2018

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Tagetitoxin inhibition of RNA polymerase III transcription results from enhanced pausing at discrete sites and is template-dependent

28 November 2018

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inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Determination of intrinsic transcription termination efficiency by RNA polymerase elongation rate

1 reference

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https://pubmed.ncbi.nlm.nih.gov/21976682

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

A central role of the RNA polymerase trigger loop in active-site rearrangement during transcriptional pausing

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21976682