The Rac1 splice form Rac1b promotes K-ras-induced lung tumorigenesis (Q24596918)

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S Licciulli

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J L Avila

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M Cho

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S Troutman

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P Jiang

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A V Kossenkov

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L C Showe

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Q Liu

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A Vachani

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S M Albelda

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J L Kissil

describes a project that uses

12

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language of work or name

English

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publication date

14 February 2013

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published in

Oncogene

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volume

32

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issue

7

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page(s)

903-9

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ImageJ

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Europe PubMed Central

11 June 2022

https://www.ebi.ac.uk/europepmc/webservices/rest/PMC3384754/fullTextXML

based on heuristic

inferred from PubMed Central ID database lookup

cites work

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Alternative splicing of Rac1 generates Rac1b, a self-activating GTPase

24 March 2017

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Rho, rac, and cdc42 GTPases regulate the assembly of multimolecular focal complexes associated with actin stress fibers, lamellipodia, and filopodia

24 March 2017

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The small GTP-binding protein rac regulates growth factor-induced membrane ruffling

24 March 2017

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Rac1b and reactive oxygen species mediate MMP-3-induced EMT and genomic instability

24 March 2017

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The 19-amino acid insertion in the tumor-associated splice isoform Rac1b confers specific binding to p120 catenin

7 April 2017

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Pak protein kinases and their role in cancer

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B-Raf(V600E) cooperates with alternative spliced Rac1b to sustain colorectal cancer cell survival

27 September 2017

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Activation of tumor-specific splice variant Rac1b by dishevelled promotes canonical Wnt signaling and decreased adhesion of colorectal cancer cells

27 September 2017

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Rac1b, a tumor associated, constitutively active Rac1 splice variant, promotes cellular transformation

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Rho-family GTPases: it's not only Rac and Rho (and I like it).

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Analysis of lung tumor initiation and progression using conditional expression of oncogenic K-ras

27 September 2017

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Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

27 September 2017

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Rac1 in human breast cancer: overexpression, mutation analysis, and characterization of a new isoform, Rac1b

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Cloning of a novel human Rac1b splice variant with increased expression in colorectal tumors

27 September 2017

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Expression of Rac1b stimulates NF-kappaB-mediated cell survival and G1/S progression

27 September 2017

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Requirement for Rac1 in a K-ras induced lung cancer in the mouse.

30 May 2018

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PAK is required for the disruption of E-cadherin adhesion by the small GTPase Rac.

21 January 2018

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Critical Roles for Rac1 and Rac2 GTPases in B Cell Development and Signaling

21 January 2018

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https://api.crossref.org/works/10.1038%2FONC.2012.99

31 March 2020

Identifiers

DOI

10.1038/ONC.2012.99

1 reference

Dimensions Publication ID

2143667

1007786392

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2143667

1 reference

1 reference

1 reference