The molecular biology of human herpesvirus-6 latency and telomere integration (Q24596930)

Human herpesvirus 6A accelerates AIDS progression in macaques

Europe PubMed Central

title

The molecular biology of human herpesvirus-6 latency and telomere integration (English)

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Peter G Medveczky

2

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author name string

Jesse H Arbuckle

series ordinal

1

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language of work or name

English

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publication date

August 2011

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published in

Microbes and Infection

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volume

13

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issue

8-9

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page(s)

731-41

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cites work

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24 March 2017

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24 March 2017

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Human herpesvirus 6 infects the central nervous system of multiple sclerosis patients in the early stages of the disease

24 March 2017

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27 September 2017

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The DR1 and DR6 first exons of human herpesvirus 6A are not required for virus replication in culture and are deleted in virus stocks that replicate well in T-cell lines

27 September 2017

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TERRA RNA binding to TRF2 facilitates heterochromatin formation and ORC recruitment at telomeres

27 September 2017

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Site-specific integration of adeno-associated virus involves partial duplication of the target locus.

27 September 2017

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Transcription of HERV-E and HERV-E-related sequences in malignant and non-malignant human haematopoietic cells

27 September 2017

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Human telomere structure and biology

27 September 2017

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Reactivation of human herpesvirus-6 in natalizumab treated multiple sclerosis patients

27 September 2017

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Telomere length, telomeric proteins and genomic instability during the multistep carcinogenic process

27 September 2017

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Epstein-Barr virus integrates frequently into chromosome 4q, 2q, 1q and 7q of Burkitt's lymphoma cell line (Raji).

27 September 2017

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Human herpesvirus 6 chromosomal integration in immunocompetent patients results in high levels of viral DNA in blood, sera, and hair follicles

27 September 2017

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Marek's disease virus: from miasma to model

27 September 2017

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Latency-associated nuclear antigen (LANA) of Kaposi's sarcoma-associated herpesvirus interacts with origin recognition complexes at the LANA binding sequence within the terminal repeats

27 September 2017

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The nucleosomal surface as a docking station for Kaposi's sarcoma herpesvirus LANA.

27 September 2017

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Human herpesvirus 6 (HHV-6) U94/REP protein inhibits betaherpesvirus replication

27 September 2017

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Kaposi's sarcoma-associated herpesvirus-encoded latency-associated nuclear antigen inhibits lytic replication by targeting Rta: a potential mechanism for virus-mediated control of latency

27 September 2017

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Detection of a gene cluster that is dispensable for human herpesvirus 6 replication and latency

27 September 2017

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High frequency of human herpesvirus 6 DNA in multiple sclerosis plaques isolated by laser microdissection.

27 September 2017

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27 September 2017

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Human herpesvirus-6 and -7 in transplantation

27 September 2017

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Sequence-specific recognition and cleavage of telomeric repeat (TTAGG)(n) by endonuclease of non-long terminal repeat retrotransposon TRAS1.

27 September 2017

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Expression of human herpesvirus 6B rep within infected cells and binding of its gene product to the TATA-binding protein in vitro and in vivo

27 September 2017

1 reference

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Increased lymphoproliferative response to human herpesvirus type 6A variant in multiple sclerosis patients

27 September 2017

1 reference

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Efficient persistence of extrachromosomal KSHV DNA mediated by latency-associated nuclear antigen

27 September 2017

1 reference

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Mapping EBNA-1 domains involved in binding to metaphase chromosomes.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130849

U94 of human herpesvirus 6 is expressed in latently infected peripheral blood mononuclear cells and blocks viral gene expression in transformed lymphocytes in culture

27 September 2017

1 reference

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Integration of human herpesvirus 6 in a Burkitt's lymphoma cell line

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130849

Latent Marek's disease virus can be activated from its chromosomally integrated state in herpesvirus-transformed lymphoma cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130849

Status of Marek's disease virus in established lymphoma cell lines: herpesvirus integration is common

27 September 2017

1 reference

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Human herpesvirus 6 infects cervical epithelial cells and transactivates human papillomavirus gene expression

27 September 2017

1 reference

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The DNA sequence of human herpesvirus-6: structure, coding content, and genome evolution

27 September 2017

1 reference

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Human herpesvirus 6A ts suppresses both transformation by H-ras and transcription by the H-ras and human immunodeficiency virus type 1 promoters.

27 September 2017

1 reference

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Detection of circular and linear herpesvirus DNA molecules in mammalian cells by gel electrophoresis.

27 September 2017

1 reference

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A noninverting genome of a viable herpes simplex virus 1: presence of head-to-tail linkages in packaged genomes and requirements for circularization after infection

27 September 2017

1 reference

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Predominant CD4 T-lymphocyte tropism of human herpesvirus 6-related virus.

27 September 2017

1 reference

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The AAV origin binding protein Rep68 is an ATP-dependent site-specific endonuclease with DNA helicase activity

27 September 2017

1 reference

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Acquisition of the human adeno-associated virus type-2 rep gene by human herpesvirus type-6

27 September 2017

1 reference

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When Epstein-Barr virus persistently infects B-cell lines, it frequently integrates

27 September 2017

1 reference

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Targeted integration of adeno-associated virus (AAV) into human chromosome 19

27 September 2017

1 reference

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Anatomy of Herpes Simplex Virus DNA XII. Accumulation of Head-to-Tail Concatemers in Nuclei of Infected Cells and Their Role in the Generation of the Four Isomeric Arrangements of Viral DNA

27 September 2017

1 reference

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Human herpesvirus 6 (HHV-6) is a helper virus for adeno-associated virus type 2 (AAV-2) and the AAV-2 rep gene homologue in HHV-6 can mediate AAV-2 DNA replication and regulate gene expression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130849

Human herpesvirus 6 (HHV-6) is transmitted from parent to child in an integrated form and characterization of cases with chromosomally integrated HHV-6 DNA.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130849

Human herpesvirus-6 rep/U94 gene product has single-stranded DNA-binding activity

30 May 2018

1 reference

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Three cases of human herpesvirus-6 latent infection: integration of viral genome in peripheral blood mononuclear cell DNA.

30 May 2018

1 reference

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Serological and virological investigation of the role of the herpesviruses EBV, CMV and HHV-6 in post-infective fatigue syndrome

30 May 2018

1 reference

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Transmission of chromosomally integrated human herpesvirsus 6 (HHV-6) variant A from a parent to children leading to misdiagnosis of active HHV-6 infection

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130849

Length variability of telomeric repeat sequences of human herpesvirus 6 DNA.

28 November 2018

1 reference

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Contribution of human herpesvirus 6 (HHV-6) viral load in whole blood and serum to investigate integrated HHV-6 transmission after haematopoietic stem cell transplantation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130849

Human herpesvirus 6 integrates within telomeric regions as evidenced by five different chromosomal sites

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130849

Cell-to-cell fusion as a link between viruses and cancer.

28 November 2018

1 reference

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Transmission of integrated human herpesvirus-6 in allogeneic hematopoietic stem cell transplantation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3130849

The prevalence of chromosomally integrated human herpesvirus 6 genomes in the blood of UK blood donors.

28 November 2018

1 reference

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Transmission of integrated human herpesvirus 6 through stem cell transplantation: implications for laboratory diagnosis.

28 November 2018

1 reference

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Telomeric proteins regulate episomal maintenance of Epstein-Barr virus origin of plasmid replication

28 November 2018

1 reference

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CD46 is a cellular receptor for human herpesvirus 6.

28 November 2018

1 reference

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Latent infection and reactivation of human herpesvirus 6 in two novel myeloid cell lines.

28 November 2018

1 reference

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Inheritance of chromosomally integrated human herpesvirus 6 DNA

28 November 2018

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12 December 2020

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Unexpected occasional persistence of high levels of HHV-6 DNA in sera: detection of variants A and B

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12 December 2020

Prevalence of HHV-6 integrated chromosomally among children treated for acute lymphoblastic or myeloid leukemia in the Czech Republic

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12 December 2020

Strong interaction between human herpesvirus 6 and peripheral blood monocytes/macrophages during acute infection

1 reference

12 December 2020

Identification of human herpesvirus-6 as a causal agent for exanthem subitum

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12 December 2020

Human herpesvirus-6 strain groups: a nomenclature

1 reference

12 December 2020

Chromosomal transmission of human herpesvirus 6 DNA in acute lymphoblastic leukaemia

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12 December 2020

10.1016/J.MICINF.2011.03.006

Identifiers

DOI

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4184946

4184946

1 reference

1 reference

1 reference