Characterization of the human insulin-induced gene 2 (INSIG2) promoter: the role of Ets-binding motifs (Q24598294)

positive regulation of transcription by RNA polymerase II

GOA release 2020-03-11

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GOA release 2020-03-11

1 reference

Ana Fernández-Alvarez

1

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María Soledad Alvarez

2

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Carme Cucarella

3

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Marta Casado

Journal of Biological Chemistry

4

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language of work or name

English

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publication date

16 April 2010

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published in

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volume

285

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issue

16

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page(s)

11765-74

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cites work

Transcriptional regulation of the cytosolic chaperonin theta subunit gene, Cctq, by Ets domain transcription factors Elk-1, Sap-1a, and Net in the absence of serum response factor

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Liver-specific mRNA for Insig-2 down-regulated by insulin: implications for fatty acid synthesis

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A proteolytic pathway that controls the cholesterol content of membranes, cells, and blood

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Convergence of MAP kinase pathways on the ternary complex factor Sap-1a

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Selective response of ternary complex factor Sap1a to different mitogen-activated protein kinase subgroups

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Net, a new ets transcription factor that is activated by Ras

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Structures of SAP-1 bound to DNA targets from the E74 and c-fos promoters: insights into DNA sequence discrimination by Ets proteins

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Decreased IRS-2 and increased SREBP-1c lead to mixed insulin resistance and sensitivity in livers of lipodystrophic and ob/ob mice

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Novel delayed-early and highly insulin-induced growth response genes. Identification of HRS, a potential regulator of alternative pre-mRNA splicing

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Insulin enhances the biogenesis of nuclear sterol regulatory element-binding protein (SREBP)-1c by posttranscriptional down-regulation of Insig-2A and its dissociation from SREBP cleavage-activating protein (SCAP).SREBP-1c complex

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Elk1 and SRF transcription factors convey basal transcription and mediate glucose response via their binding sites in the human LXRB gene promoter

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RNAPol-ChIP: a novel application of chromatin immunoprecipitation to the analysis of real-time gene transcription.

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Ets ternary complex transcription factors

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New perspectives in the regulation of hepatic glycolytic and lipogenic genes by insulin and glucose: a role for the transcription factor sterol regulatory element binding protein-1c

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Absence of sterol regulatory element-binding protein-1 (SREBP-1) ameliorates fatty livers but not obesity or insulin resistance in Lep(ob)/Lep(ob) mice

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Increased expression of the sterol regulatory element-binding protein-1 gene in insulin receptor substrate-2(-/-) mouse liver

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Signal transduction and the Ets family of transcription factors

27 September 2017

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FLI1 and EWS-FLI1 function as ternary complex factors and ELK1 and SAP1a function as ternary and quaternary complex factors on the Egr1 promoter serum response elements

27 September 2017

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The Ets family of transcription factors

27 September 2017

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The IRS-1 signaling system

27 September 2017

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Insulin action and the insulin signaling network

27 September 2017

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Multiple protein-DNA interactions in the TATAA-less mouse thymidylate synthase promoter

27 September 2017

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Transcriptional activation through ETS domain binding sites in the cytochrome c oxidase subunit IV gene

27 September 2017

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A consensus insulin response element is activated by an Ets-related transcription factor.

27 September 2017

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The P34G mutation reduces the transforming activity of K-Ras and N-Ras in NIH 3T3 cells but not of H-Ras.

27 September 2017

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Ternary complex factors Elk-1 and Sap-1a mediate growth hormone-induced transcription of egr-1 (early growth response factor-1) in 3T3-F442A preadipocytes

30 May 2018

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Hypertriglyceridemic waist: A marker of the atherogenic metabolic triad (hyperinsulinemia; hyperapolipoprotein B; small, dense LDL) in men?

30 May 2018

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Human obesity and type 2 diabetes are associated with alterations in SREBP1 isoform expression that are reproduced ex vivo by tumor necrosis factor-alpha

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109.067447

Quantitative trait loci for obesity- and diabetes-related traits and their dietary responses to high-fat feeding in LGXSM recombinant inbred mouse strains

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109.067447

Regulation of the rat SREBP-1c promoter in primary rat hepatocytes

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109.067447

Integrating QTL and high-density SNP analyses in mice to identify Insig2 as a susceptibility gene for plasma cholesterol levels

21 January 2018

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https://api.crossref.org/works/10.1074%2FJBC.M109.067447

A common genetic variant is associated with adult and childhood obesity

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.067447

Insulin signal transduction through protein kinase cascades

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.067447

Contribution of cyclooxygenase 2 to liver regeneration after partial hepatectomy.

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.067447

Structures of SAP-1 Bound to DNA Targets from the E74 and c-fos Promoters

21 January 2018

1 reference

https://api.crossref.org/works/10.1074%2FJBC.M109.067447

21 January 2018

Identifiers

DOI

10.1074/JBC.M109.067447

1 reference

release_gvemy2ausvd7hkap3kbkos2aya

Fatcat ID

0 references

1 reference

1 reference

PubMed publication ID

20145255

1 reference