Attenuation of osteoarthritis progression by reduction of discoidin domain receptor 2 in mice (Q24599945)

2

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Ilona Polur

3

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Doil Kim

4

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Peter L Lee

5

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Kimberly Chung

6

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Yefu Li

Spondylo-epi-metaphyseal dysplasia (SEMD) matrilin 3 type: homozygote matrilin 3 mutation in a novel form of SEMD

7

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language of work or name

English

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publication date

September 2010

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published in

Arthritis & Rheumatology

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volume

62

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page(s)

2736-44

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issue

9

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cites work

1 reference

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Human HtrA, an evolutionarily conserved serine protease identified as a differentially expressed gene product in osteoarthritic cartilage

24 March 2017

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The discoidin domain receptor tyrosine kinases are activated by collagen

24 March 2017

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Cloning, expression, and type II collagenolytic activity of matrix metalloproteinase-13 from human osteoarthritic cartilage

24 March 2017

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The role of human HtrA1 in arthritic disease

24 March 2017

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The D2 period of collagen II contains a specific binding site for the human discoidin domain receptor, DDR2

24 March 2017

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The collagen receptor DDR2 regulates proliferation and its elimination leads to dwarfism

24 March 2017

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An orphan receptor tyrosine kinase family whose members serve as nonintegrin collagen receptors

24 March 2017

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Mice lacking alpha 1 (IX) collagen develop noninflammatory degenerative joint disease

24 March 2017

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Mutations in exon 17B of cartilage oligomeric matrix protein (COMP) cause pseudoachondroplasia

24 March 2017

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Matrix metalloproteinase 13-deficient mice are resistant to osteoarthritic cartilage erosion but not chondrocyte hypertrophy or osteophyte development.

24 March 2017

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OA clinical trials: current targets and trials for OA. Choosing molecular targets: what have we learned and where we are headed?

27 September 2017

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Developmental and osteoarthritic changes in Col6a1-knockout mice: biomechanics of type VI collagen in the cartilage pericellular matrix.

27 September 2017

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A novel dwarfism with gonadal dysfunction due to loss-of-function allele of the collagen receptor gene, Ddr2, in the mouse

27 September 2017

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Comparative proteomic characterization of articular cartilage tissue from normal donors and patients with osteoarthritis

27 September 2017

1 reference

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Update on the biology of the chondrocyte and new approaches to treating cartilage diseases

27 September 2017

1 reference

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Altered endochondral bone development in matrix metalloproteinase 13-deficient mice

27 September 2017

1 reference

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Postnatal expression in hyaline cartilage of constitutively active human collagenase-3 (MMP-13) induces osteoarthritis in mice

27 September 2017

1 reference

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The new collagenase, collagenase-3, is expressed and synthesized by human chondrocytes but not by synoviocytes. A role in osteoarthritis

27 September 2017

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The biology of osteoarthritis

27 September 2017

1 reference

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Ultrastructure of adult human articular cartilage matrix after cryotechnical processing

27 September 2017

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Role of HTRA1, a serine protease, in the progression of articular cartilage degeneration

27 September 2017

1 reference

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Early-onset osteoarthritis of mouse temporomandibular joint induced by partial discectomy

30 May 2018

1 reference

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Articular cartilage chondrons: form, function and failure

30 May 2018

1 reference

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Chondrons from articular cartilage (II): Analysis of the glycosaminoglycans in the cellular microenvironment of isolated canine chondrons.

30 May 2018

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Chondrons from articular cartilage. III. Morphologic changes in the cellular microenvironment of chondrons isolated from osteoarthritic cartilage

30 May 2018

1 reference

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Characterization of high affinity binding motifs for the discoidin domain receptor DDR2 in collagen

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946478

Peptides of type II collagen can induce the cleavage of type II collagen and aggrecan in articular cartilage

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946478

Expression of mouse HtrA1 serine protease in normal bone and cartilage and its upregulation in joint cartilage damaged by experimental arthritis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2946478

Abnormal collagen fibrils in cartilage of matrilin-1/matrilin-3-deficient mice

28 November 2018

1 reference

12 December 2020

Increased expression of discoidin domain receptor 2 is linked to the degree of cartilage damage in human knee joints: a potential role in osteoarthritis pathogenesis

1 reference

12 December 2020

A critical role for collagen II in cartilage matrix degradation: collagen II induces pro-inflammatory cytokines and MMPs in primary human chondrocytes

1 reference

12 December 2020

Effect of collagen turnover on the accumulation of advanced glycation end products

1 reference

12 December 2020

Osteoarthritis-like changes and decreased mechanical function of articular cartilage in the joints of mice with the chondrodysplasia gene (cho)

1 reference

12 December 2020

Activation of the discoidin domain receptor 2 induces expression of matrix metalloproteinase 13 associated with osteoarthritis in mice

1 reference

12 December 2020

Mice deficient in biglycan and fibromodulin as a model for temporomandibular joint osteoarthritis

1 reference

12 December 2020

Premature osteoarthritis in the Disproportionate micromelia (Dmm) mouse

1 reference

12 December 2020

Pathogenesis of osteoarthritis-like changes in the joints of mice deficient in type IX collagen

1 reference

12 December 2020

Increased expression of the collagen receptor discoidin domain receptor 2 in articular cartilage as a key event in the pathogenesis of osteoarthritis

1 reference

12 December 2020

Identifiers

DOI

10.1002/ART.27582

1 reference

4561387

4561387

1 reference

1 reference

1 reference