Functional interaction between RAFT1/FRAP/mTOR and protein kinase cdelta in the regulation of cap-dependent initiation of translation (Q24600427)

1

0 references

P Pandey

2

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D Sabatini

3

0 references

M Kumar

4

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P K Majumder

5

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A Bharti

6

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G Carmichael

7

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D Kufe

8

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S Kharbanda

Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism

9

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language of work or name

English

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publication date

1 March 2000

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published in

The EMBO Journal

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volume

19

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issue

5

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page(s)

1087-97

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cites work

1 reference

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Interaction of polyadenylate-binding protein with the eIF4G homologue PAIP enhances translation

7 April 2017

1 reference

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RAFT1 phosphorylation of the translational regulators p70 S6 kinase and 4E-BP1

7 April 2017

1 reference

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3-Phosphoinositide-dependent protein kinase-1 (PDK1): structural and functional homology with the Drosophila DSTPK61 kinase

7 April 2017

1 reference

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Insulin-dependent stimulation of protein synthesis by phosphorylation of a regulator of 5'-cap function

7 April 2017

1 reference

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TOR controls translation initiation and early G1 progression in yeast

7 April 2017

1 reference

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7 April 2017

1 reference

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Protein kinase C isotypes controlled by phosphoinositide 3-kinase through the protein kinase PDK1

7 April 2017

1 reference

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Activation of the epidermal growth factor receptor signal transduction pathway stimulates tyrosine phosphorylation of protein kinase C delta

7 April 2017

1 reference

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Rapamycin blocks the phosphorylation of 4E-BP1 and inhibits cap-dependent initiation of translation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Protein kinase C--a question of specificity

7 April 2017

1 reference

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A mammalian protein targeted by G1-arresting rapamycin-receptor complex

7 April 2017

1 reference

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Isolation of a protein target of the FKBP12-rapamycin complex in mammalian cells

7 April 2017

1 reference

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Protein kinase C and lipid signaling for sustained cellular responses

7 April 2017

1 reference

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RAFT1: a mammalian protein that binds to FKBP12 in a rapamycin-dependent fashion and is homologous to yeast TORs

7 April 2017

1 reference

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Targets for Cell Cycle Arrest by the Immunosuppressant Rapamycin in Yeast

7 April 2017

1 reference

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Rapamycin selectively inhibits interleukin-2 activation of p70 S6 kinase

7 April 2017

1 reference

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Rapamycin-FKBP specifically blocks growth-dependent activation of and signaling by the 70 kd S6 protein kinases

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Functional interaction between DNA-PK and c-Abl in response to DNA damage

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Proteolytic activation of protein kinase C delta by an ICE/CED 3-like protease induces characteristics of apoptosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Control of the translational regulators PHAS-I and PHAS-II by insulin and cAMP in 3T3-L1 adipocytes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Cloning and expression of cDNA encoding protein synthesis elongation factor-2 kinase

7 April 2017

1 reference

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Phosphorylation of the translational repressor PHAS-I by the mammalian target of rapamycin

7 April 2017

1 reference

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Target of rapamycin in yeast, TOR2, is an essential phosphatidylinositol kinase homolog required for G1 progression

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Mammalian TOR controls one of two kinase pathways acting upon nPKCdelta and nPKCepsilon

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Intracellular signalling: PDK1--a kinase at the hub of things

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Functional role for protein kinase Cbeta as a regulator of stress-activated protein kinase activation and monocytic differentiation of myeloid leukemia cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Inactivation of DNA-dependent protein kinase by protein kinase Cdelta: implications for apoptosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Regulation of DNA-dependent protein kinase by the Lyn tyrosine kinase

27 September 2017

1 reference

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Translocation of PKC delta by insulin in a rat hepatoma cell line

27 September 2017

1 reference

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Evidence of insulin-stimulated phosphorylation and activation of the mammalian target of rapamycin mediated by a protein kinase B signaling pathway

27 September 2017

1 reference

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Regulation of eIF-4E BP1 phosphorylation by mTOR.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Rapamycin suppresses 5'TOP mRNA translation through inhibition of p70s6k.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Tumor promotion by depleting cells of protein kinase C delta

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Association between v-Src and protein kinase C delta in v-Src-transformed fibroblasts

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Nuclear antisense RNA induces extensive adenosine modifications and nuclear retention of target transcripts

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Phosphatidylinositol 3-kinase related kinases

27 September 2017

1 reference

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A signaling pathway to translational control

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

The stress response to ionizing radiation involoves c-Abl-dependent phosphorylation of SHPTP1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Activation of the translational suppressor 4E-BP1 following infection with encephalomyocarditis virus and poliovirus.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

4E-BP1 phosphorylation is mediated by the FRAP-p70s6k pathway and is independent of mitogen-activated protein kinase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Translation initiation of ornithine decarboxylase and nucleocytoplasmic transport of cyclin D1 mRNA are increased in cells overexpressing eukaryotic initiation factor 4E.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Proteolytic activation of protein kinase C delta by an ICE-like protease in apoptotic cells.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Ras-dependent signal transduction is indispensable but not sufficient for the activation of AP1/Jun by PKC delta

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Rapamycin selectively represses translation of the "polypyrimidine tract" mRNA family

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Molecular cloning and tissue distribution of PHAS-I, an intracellular target for insulin and growth factors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Nuclear localization of p85s6k: functional requirement for entry into S phase.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Rottlerin, a novel protein kinase inhibitor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

mRNA translation: influence of the 5' and 3' untranslated regions

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Rapamycin selectively inhibits translation of mRNAs encoding elongation factors and ribosomal proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Stimulation of the platelet-derived growth factor beta receptor signaling pathway activates protein kinase C-delta

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

The first and third uORFs in RSV leader RNA are efficiently translated: implications for translational regulation and viral RNA packaging

27 September 2017

1 reference

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Cyclosporin A, FK506 and rapamycin: more than just immunosuppression

27 September 2017

1 reference

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The protein kinase C and protein kinase C related gene families.

27 September 2017

1 reference

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The principal target of rapamycin-induced p70s6k inactivation is a novel phosphorylation site within a conserved hydrophobic domain.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

The heterogeneity and differential expression of multiple species of the protein kinase C family

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Cell division arrest induced by phorbol ester in CHO cells overexpressing protein kinase C-delta subspecies

27 September 2017

1 reference

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Protein kinase C delta specifically associates with phosphatidylinositol 3-kinase following cytokine stimulation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Activation of the c-Abl tyrosine kinase in the stress response to DNA-damaging agents

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Control of p70 s6 kinase by kinase activity of FRAP in vivo

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

The mRNA 5' cap-binding protein eIF4E and control of cell growth

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

TOR signalling and control of cell growth

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Protein kinase C activates the MEK-ERK pathway in a manner independent of Ras and dependent on Raf.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

c-Abl activation regulates induction of the SEK1/stress-activated protein kinase pathway in the cellular response to 1-beta-D-arabinofuranosylcytosine

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

PHAS-I as a link between mitogen-activated protein kinase and translation initiation

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

A new member of the protein kinase C family, nPKC theta, predominantly expressed in skeletal muscle

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Rapamycin-induced inhibition of the 70-kilodalton S6 protein kinase

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Expression of an oncogenic rasHa gene in murine keratinocytes induces tyrosine phosphorylation and reduced activity of protein kinase C delta.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

Interaction between FKBP12-rapamycin and TOR involves a conserved serine residue.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=305647

p70s6k function is essential for G1 progression

28 November 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FEMBOJ%2F19.5.1087

Growth-dependent translation of IGF-II mRNA by a rapamycin-sensitive pathway

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FEMBOJ%2F19.5.1087

Cytoplasmic regulation of mRNA function: the importance of the 3' untranslated region

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10698949

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Dissociation of the eukaryotic initiation factor-4E/4E-BP1 complex involves phosphorylation of 4E-BP1 by an mTOR-associated kinase

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/10698949

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Additions and Corrections to DNA binding exerted by a bacterial gene regulator with an extensive coiled-coil domain

1 reference

Crossref

https://api.crossref.org/works/10.1093%2FEMBOJ%2F19.5.1087

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1093/EMBOJ/19.5.1087

1 reference

1 reference

1 reference

PubMed publication ID

10698949

1 reference