A novel evolutionarily conserved domain of cell-adhesion GPCRs mediates autoproteolysis (Q24602445)

7

0 references

Demet Araç

1

object named as

Demet Araç

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Antony A. Boucard

2

object named as

Antony A Boucard

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author name string

Marc F Bolliger

3

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Jenna Nguyen

4

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S Michael Soltis

The N terminus of the adhesion G protein-coupled receptor GPR56 controls receptor signaling activity

5

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language of work or name

English

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publication date

21 March 2012

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published in

The EMBO Journal

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volume

31

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issue

6

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page(s)

1364-78

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cites work

1 reference

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The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins

7 April 2017

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7 April 2017

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Alpha-latrotoxin stimulates a novel pathway of Ca2+-dependent synaptic exocytosis independent of the classical synaptic fusion machinery

7 April 2017

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Core signaling pathways in human pancreatic cancers revealed by global genomic analyses

7 April 2017

1 reference

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An integrated genomic analysis of human glioblastoma multiforme

7 April 2017

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High-resolution crystal structure of an engineered human beta2-adrenergic G protein-coupled receptor

7 April 2017

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The genome of the social amoeba Dictyostelium discoideum

7 April 2017

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G protein-coupled receptor-dependent development of human frontal cortex

7 April 2017

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Cleavage of polycystin-1 requires the receptor for egg jelly domain and is disrupted by human autosomal-dominant polycystic kidney disease 1-associated mutations.

7 April 2017

1 reference

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A stoichiometric complex of neurexins and dystroglycan in brain

7 April 2017

1 reference

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Identification of a human homologue of the sea urchin receptor for egg jelly: a polycystic kidney disease-like protein

7 April 2017

1 reference

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The three-dimensional structure of the autoproteolytic, nuclear pore-targeting domain of the human nucleoporin Nup98

7 April 2017

1 reference

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The genomic landscapes of human breast and colorectal cancers

7 April 2017

1 reference

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Automated structure solution with autoSHARP

7 April 2017

1 reference

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Coot: model-building tools for molecular graphics

7 April 2017

1 reference

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Automated main-chain model building by template matching and iterative fragment extension

7 April 2017

1 reference

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Substructure solution with SHELXD

7 April 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

7 April 2017

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The PSIPRED protein structure prediction server

27 September 2017

1 reference

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Protein structure comparison by alignment of distance matrices

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

Essential regulation of CNS angiogenesis by the orphan G protein-coupled receptor GPR124.

7 April 2017

1 reference

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A common variant of the latrophilin 3 gene, LPHN3, confers susceptibility to ADHD and predicts effectiveness of stimulant medication

7 April 2017

1 reference

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A G protein-coupled receptor is essential for Schwann cells to initiate myelination

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

GPCR engineering yields high-resolution structural insights into beta2-adrenergic receptor function

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

ADAMs: key components in EGFR signalling and development

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

Targeted deletion of the epididymal receptor HE6 results in fluid dysregulation and male infertility

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

Regulation of dendritic maintenance and growth by a mammalian 7-pass transmembrane cadherin

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

Autocatalytic cleavage of the EMR2 receptor occurs at a conserved G protein-coupled receptor proteolytic site motif

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

alpha-Latrotoxin and its receptors: neurexins and CIRL/latrophilins

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

Flamingo, a seven-pass transmembrane cadherin, regulates planar cell polarity under the control of Frizzled

7 April 2017

1 reference

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A latrophilin/CL-1-like GPS domain in polycystin-1

7 April 2017

1 reference

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A novel ubiquitously expressed alpha-latrotoxin receptor is a member of the CIRL family of G-protein-coupled receptors

7 April 2017

1 reference

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A novel brain-specific p53-target gene, BAI1, containing thrombospondin type 1 repeats inhibits experimental angiogenesis

7 April 2017

1 reference

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alpha-Latrotoxin stimulates exocytosis by the interaction with a neuronal G-protein-coupled receptor

7 April 2017

1 reference

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ETL, a novel seven-transmembrane receptor that is developmentally regulated in the heart. ETL is a member of the secretin family and belongs to the epidermal growth factor-seven-transmembrane subfamily

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

Alpha-latrotoxin receptor, latrophilin, is a novel member of the secretin family of G protein-coupled receptors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

Autoproteolysis in hedgehog protein biogenesis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

The G-protein-coupled receptors in the human genome form five main families. Phylogenetic analysis, paralogon groups, and fingerprints

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

Diverse somatic mutation patterns and pathway alterations in human cancers

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

Structural diversity of G protein-coupled receptors and significance for drug discovery

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

Density modification for macromolecular phase improvement

7 April 2017

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

7 April 2017

https://api.crossref.org/works/10.1038%2FEMBOJ.2012.26

inferred from DOI database lookup

7 January 2021

based on heuristic

Latrophilin signaling links anterior-posterior tissue polarity and oriented cell divisions in the C. elegans embryo

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

Adhesion-GPCRs: emerging roles for novel receptors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

Essential role of cleavage of Polycystin-1 at G protein-coupled receptor proteolytic site for kidney tubular structure.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

Mechanisms of peptide and nonpeptide ligand binding to Class B G-protein-coupled receptors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

Vasculostatin, a proteolytic fragment of brain angiogenesis inhibitor 1, is an antiangiogenic and antitumorigenic factor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

Proteolytic cleavage of the EMR2 receptor requires both the extracellular stalk and the GPS motif

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

Post-translational proteolytic processing of the calcium-independent receptor of alpha-latrotoxin (CIRL), a natural chimera of the cell adhesion protein and the G protein-coupled receptor. Role of the G protein-coupled receptor proteolysis site [...]

27 September 2017

1 reference

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Mutation analysis of the entire PKD1 gene: genetic and diagnostic implications

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

Conserved domain structure of beta-neurexins. Unusual cleaved signal sequences in receptor-like neuronal cell-surface proteins.

27 September 2017

1 reference

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PROMALS web server for accurate multiple protein sequence alignments

27 September 2017

1 reference

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Protein splicing and autoproteolysis mechanisms.

30 May 2018

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GPR98 mutations cause Usher syndrome type 2 in males.

30 May 2018

1 reference

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Crystal structure of a rhomboid family intramembrane protease.

28 November 2018

1 reference

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N-terminal insertion and C-terminal ankyrin-like repeats of alpha-latrotoxin are critical for Ca2+-dependent exocytosis.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

Protein-tyrosine phosphatase-sigma is a novel member of the functional family of alpha-latrotoxin receptors

28 November 2018

1 reference

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The Drosophila tissue polarity gene starry night encodes a member of the protocadherin family

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

alpha-Latrotoxin receptor CIRL/latrophilin 1 (CL1) defines an unusual family of ubiquitous G-protein-linked receptors. G-protein coupling not required for triggering exocytosis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3321182

Neurexins are functional alpha-latrotoxin receptors

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22333914

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Processing of X-ray diffraction data collected in oscillation mode

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22333914

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/EMBOJ.2012.26

1 reference

1 reference

1 reference

PubMed publication ID

22333914

1 reference