Discovery of natural product anticancer agents from biodiverse organisms (Q24605488)

Europe PubMed Central

title

Discovery of natural product anticancer agents from biodiverse organisms (English)

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main subject

spiruchostatin B

1 reference

Current Opinion in Drug Discovery and Development

ChEBI release 2020-05-28

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A Douglas Kinghorn

1

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Young-Won Chin

series ordinal

2

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Steven M Swanson

series ordinal

3

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language of work or name

English

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publication date

March 2009

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published in

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Symplocamide A, a potent cytotoxin and chymotrypsin inhibitor from the marine Cyanobacterium Symploca sp

volume

12

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issue

2

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page(s)

189-96

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cites work

1 reference

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Therapeutic suppression of translation initiation modulates chemosensitivity in a mouse lymphoma model

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Synthesis enables identification of the cellular target of leucascandrolide A and neopeltolide

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Silvestrol, a potential anticancer rocaglate derivative from Aglaia foveolata, induces apoptosis in LNCaP cells through the mitochondrial/apoptosome pathway without activation of executioner caspase-3 or -7.

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Apoptotic anticancer effect of alvaradoin E isolated from Alvaradoa haitiensis

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27 September 2017

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30 May 2018

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Sodium pancratistatin 3,4-o-cyclic phosphate, a water-soluble synthetic derivative of pancratistatin, is highly effective in a human colon tumor model.

28 November 2018

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28 November 2018

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Total Synthesis of (−)-Episilvestrol and (−)-Silvestrol

28 November 2018

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Total synthesis of the originally proposed and revised structures of palmerolide A.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877274

Silvestrol regulates G2/M checkpoint genes independent of p53 activity.

28 November 2018

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Pancratistatin causes early activation of caspase-3 and the flipping of phosphatidyl serine followed by rapid apoptosis specifically in human lymphoma cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2877274

Evaluation of the potential cancer chemotherapeutic efficacy of natural product isolates employing in vivo hollow fiber tests.

28 November 2018

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Antineoplastic agents. 450. Synthesis of (+)-pancratistatin from (+)-narciclasine as relay(1a).

28 November 2018

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Growth and chemotherapeutic response of cells in a hollow-fiber in vitro solid tumor model.

28 November 2018

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Neopeltolide, a macrolide from a lithistid sponge of the family Neopeltidae

28 November 2018

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12 December 2020

Unraveling a molecular target of macrolides

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12 December 2020

Alvaradoins A-D. Anthracenone C arabinosides from alvaradoa jamaicensis

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12 December 2020

Total synthesis of spiruchostatin A, a potent histone deacetylase inhibitor

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12 December 2020

First total synthesis of antitumor natural product (+)- and (-)-pericosine A: determination of absolute stereo structure

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12 December 2020

Total synthesis of spiruchostatin B, a potent histone deacetylase inhibitor, from a microorganism

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12 December 2020

Combining HPLC-PDA-MS-SPE-NMR with Circular Dichroism for Complete Natural Product Characterization in Crude Extracts: Levorotatory Gossypol inThespesia danis

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12 December 2020

Total synthesis of (+)-neopeltolide by a Prins macrocyclization

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12 December 2020

1H-cyclopenta[b]benzofuran lignans from Aglaia species inhibit cell proliferation and alter cell cycle distribution in human monocytic leukemia cell lines

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12 December 2020

Endophyte Fungal Isolates fromPodophyllumpeltatumProduce Podophyllotoxin

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12 December 2020

Antineoplastic agents, 120. Pancratium littorale

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12 December 2020

Stereocontrolled total synthesis of pancratistatin

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12 December 2020

Formal total synthesis of neopeltolide

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12 December 2020

Palmerolide A, a Cytotoxic Macrolide from the Antarctic TunicateSynoicumadareanum

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12 December 2020

Identifiers

2935332

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Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

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Consolidated OpenCitations Corpus – April 2017

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