Actions of a picomolar short-acting S1P₁ agonist in S1P₁-eGFP knock-in mice (Q24609856)

5

object named as

Marie-Therese Schaeffer

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author name string

Stuart M Cahalan

1

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Pedro J Gonzalez-Cabrera

2

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Gor Sarkisyan

3

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Nhan Nguyen

4

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Liming Huang

6

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Adam Yeager

7

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Bryan Clemons

8

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Fiona Scott

9

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Hugh Rosen

Full pharmacological efficacy of a novel S1P1 agonist that does not require S1P-like headgroup interactions

10

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language of work or name

English

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publication date

May 2011

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published in

Nature Chemical Biology

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volume

7

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page(s)

254-6

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issue

5

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cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430385

Edg-1, the G protein-coupled receptor for sphingosine-1-phosphate, is essential for vascular maturation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430385

A placebo-controlled trial of oral fingolimod in relapsing multiple sclerosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430385

Expression of the sphingosine 1-phosphate receptor, S1P1, on T-cells controls thymic emigration

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430385

EDG1 is a functional sphingosine-1-phosphate receptor that is linked via a Gi/o to multiple signaling pathways, including phospholipase C activation, Ca2+ mobilization, Ras-mitogen-activated protein kinase activation, and adenylate cyclase inhibitio

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430385

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430385

Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430385

Sphingosine 1-phosphate receptor 1 and 3 are upregulated in multiple sclerosis lesions

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430385

Cell-surface residence of sphingosine 1-phosphate receptor 1 on lymphocytes determines lymphocyte egress kinetics

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430385

Lymphatic endothelial cell sphingosine kinase activity is required for lymphocyte egress and lymphatic patterning

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430385

The receptor S1P1 overrides regulatory T cell-mediated immune suppression through Akt-mTOR.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430385

A critical role for the sphingosine analog AAL-R in dampening the cytokine response during influenza virus infection

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430385

Cortical sinus probing, S1P1-dependent entry and flow-based capture of egressing T cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430385

Local not systemic modulation of dendritic cell S1P receptors in lung blunts virus-specific immune responses to influenza

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430385

Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430385

Sphingosine-1-phosphate receptors and the development of the vascular system

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430385

Phase II study of oral fingolimod (FTY720) in multiple sclerosis: 3-year results

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430385

Sphingosine 1-phosphate (S1P) receptor subtypes S1P1 and S1P3, respectively, regulate lymphocyte recirculation and heart rate

30 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.547

Oral fingolimod (FTY720) in multiple sclerosis: two-year results of a phase II extension study

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.547

Type 1 sphingosine 1-phosphate G protein-coupled receptor (S1P1) mediation of enhanced IL-4 generation by CD4 T cells from S1P1 transgenic mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.547

Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.547

Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.547

Agonist-modulated targeting of the EDG-1 receptor to plasmalemmal caveolae. eNOS activation by sphingosine 1-phosphate and the role of caveolin-1 in sphingolipid signal transduction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FNCHEMBIO.547

The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G-protein-coupled receptors

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3430385

FTY720 versus MMF with Cyclosporine in de novo Renal Transplantation: A 1-Year, Randomized Controlled Trial in Europe and Australasia

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21445057

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NCHEMBIO.547

1 reference

Dimensions Publication ID

2622323

1035189174

0 references

2622323

1 reference

1 reference

1 reference