Evidence for irreversible inhibition of glycogen synthase kinase-3β by tideglusib (Q24610904)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22102280%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Evidence for irreversible inhibition of glycogen synthase kinase-3β by tideglusib (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22102280%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

0 references

6

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17 January 2020

author name string

Juan Manuel Domínguez

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22102280%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Ana Fuertes

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22102280%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Leyre Orozco

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22102280%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

María del Monte-Millán

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22102280%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

Elena Delgado

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22102280%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

language of work or name

English

0 references

publication date

18 November 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22102280%20AND%20SRC:MED&resulttype=core&format=json

Journal of Biological Chemistry

17 January 2020

number of pages

12

1 reference

based on heuristic

inferred from page(s)

published in

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22102280%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

volume

287

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22102280%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

page(s)

893-904

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22102280%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

issue

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22102280%20AND%20SRC:MED&resulttype=core&format=json

The selectivity of protein kinase inhibitors: a further update

17 January 2020

cites work

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Phosphorylation of neuronal survival factor MEF2D by glycogen synthase kinase 3beta in neuronal apoptosis

27 September 2017

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27 September 2017

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Mitochondrial hexokinase II promotes neuronal survival and acts downstream of glycogen synthase kinase-3.

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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The Wnt pool of glycogen synthase kinase 3beta is critical for trophic-deprivation-induced neuronal death

27 September 2017

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Glycogen synthase kinase-3beta, or a link between amyloid and tau pathology?

27 September 2017

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The GSK3 hypothesis of Alzheimer's disease

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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21 January 2018

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Aβ(1-42) inhibition of LTP is mediated by a signaling pathway involving caspase-3, Akt1 and GSK-3β.

21 January 2018

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Association between glycogen synthase kinase-3beta genetic polymorphism and late-onset Alzheimer's disease.

21 January 2018

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Epistasis between tau phosphorylation regulating genes (CDK5R1 and GSK-3beta) and Alzheimer's disease risk

21 January 2018

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First non-ATP competitive glycogen synthase kinase 3 beta (GSK-3beta) inhibitors: thiadiazolidinones (TDZD) as potential drugs for the treatment of Alzheimer's disease

21 January 2018

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A novel GSK-3beta inhibitor reduces Alzheimer's pathology and rescues neuronal loss in vivo.

21 January 2018

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Phase IIa clinical trial on Alzheimer's disease with NP12, a GSK3 inhibitor

21 January 2018

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SAR and 3D-QSAR studies on thiadiazolidinone derivatives: exploration of structural requirements for glycogen synthase kinase 3 inhibitors.

21 January 2018

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21 January 2018

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p35, the neuronal-specific activator of cyclin-dependent kinase 5 (Cdk5) is degraded by the ubiquitin-proteasome pathway.

21 January 2018

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Determining protein half-lives

21 January 2018

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Distribution, levels, and activity of glycogen synthase kinase-3 in the Alzheimer disease brain.

28 November 2018

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28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22102280

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Glycogen synthase kinase 3β is identical to tau protein kinase I generating several epitopes of paired helical filaments

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22102280

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M111.306472

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22102280%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22102280%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference