Tec family kinases Itk and Rlk / Txk in T lymphocytes: cross-regulation of cytokine production and T-cell fates (Q24610908)

TCR-inducible PLZF transcription factor required for innate phenotype of a subset of gammadelta T cells with restricted TCR diversity

Europe PubMed Central

title

Tec family kinases Itk and Rlk / Txk in T lymphocytes: cross-regulation of cytokine production and T-cell fates (English)

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main subject

cell biology

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author name string

Julio Gomez-Rodriguez

series ordinal

1

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Zachary J Kraus

series ordinal

2

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Pamela L Schwartzberg

series ordinal

3

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language of work or name

English

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publication date

June 2011

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published in

FEBS Journal

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volume

278

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issue

12

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page(s)

1980-9

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cites work

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The transcription factor PLZF directs the effector program of the NKT cell lineage

7 April 2017

1 reference

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The BTB-zinc finger transcriptional regulator PLZF controls the development of invariant natural killer T cell effector functions

7 April 2017

1 reference

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Skewed Th1 responses caused by excessive expression of Txk, a member of the Tec family of tyrosine kinases, in patients with Behcet's disease

7 April 2017

1 reference

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Txk, a nonreceptor tyrosine kinase of the Tec family, is expressed in T helper type 1 cells and regulates interferon gamma production in human T lymphocytes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

7 April 2017

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Requirement for Tec kinases Rlk and Itk in T cell receptor signaling and immunity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

Defective Fas ligand expression and activation-induced cell death in the absence of IL-2-inducible T cell kinase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

Differentiation of effector CD4 T cell populations (*)

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

TEC family kinases in health and disease--loss-of-function of BTK and ITK and the gain-of-function fusions ITK-SYK and BTK-SYK.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

Tec family kinases: Itk signaling and the development of NKT αβ and γδ T cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

T cells expressing the transcription factor PLZF regulate the development of memory-like CD8+ T cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

Mechanisms underlying lineage commitment and plasticity of helper CD4+ T cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

Differential expression of interleukin-17A and -17F is coupled to T cell receptor signaling via inducible T cell kinase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

ITK inhibitors in inflammation and immune-mediated disorders

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

KLF2 transcription-factor deficiency in T cells results in unrestrained cytokine production and upregulation of bystander chemokine receptors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

Enhanced development of CD4+ gammadelta T cells in the absence of Itk results in elevated IgE production

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

Girls homozygous for an IL-2-inducible T cell kinase mutation that leads to protein deficiency develop fatal EBV-associated lymphoproliferation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

Tec kinase Itk in gammadeltaT cells is pivotal for controlling IgE production in vivo.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

SLAM receptors and SAP influence lymphocyte interactions, development and function

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

The transcriptional regulator PLZF induces the development of CD44 high memory phenotype T cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

Selective expression rather than specific function of Txk and Itk regulate Th1 and Th2 responses

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

Naive and innate memory phenotype CD4+ T cells have different requirements for active Itk for their development

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

Requirements for selection of conventional and innate T lymphocyte lineages

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

Signalling through TEC kinases regulates conventional versus innate CD8(+) T-cell development

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

SLP-76 mediates and maintains activation of the Tec family kinase ITK via the T cell antigen receptor-induced association between SLP-76 and ITK

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

ITK and IL-15 support two distinct subsets of CD8+ T cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

Tec family kinases in T lymphocyte development and function

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

Kinase-independent functions for Itk in TCR-induced regulation of Vav and the actin cytoskeleton.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

Expression and function of Tec, Itk, and Btk in lymphocytes: evidence for a unique role for Tec

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

Attenuation of Immunological Symptoms of Allergic Asthma in Mice Lacking the Tyrosine Kinase ITK

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

Tec family kinases modulate thresholds for thymocyte development and selection

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

Induction of Th1 and Th2 CD4+ T cell responses: the alternative approaches

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

SAP Protein-Dependent Natural Killer T-like Cells Regulate the Development of CD8+ T Cells with Innate Lymphocyte Characteristics

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

Memory phenotype CD8+ T cells with innate function selectively develop in the absence of active Itk.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

Impaired NFATc translocation and failure of Th2 development in Itk-deficient CD4+ T cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3117960

Signaling through Itk promotes T helper 2 differentiation via negative regulation of T-bet

30 May 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08072.X

The Tec family tyrosine kinases Itk and Rlk regulate the development of conventional CD8+ T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08072.X

Altered development of CD8+ T cell lineages in mice deficient for the Tec kinases Itk and Rlk.

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08072.X

NK T cell precursors exhibit differential cytokine regulation and require Itk for efficient maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08072.X

Identification of Highly Expressed Genes in Peripheral Blood T Cells from Patients with Atopic Dermatitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1111%2FJ.1742-4658.2011.08072.X

Mutation of Tec family kinases alters T helper cell differentiation

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21362139

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cutting edge: Itk-dependent signals required for CD4+ T cells to exert, but not gain, Th2 effector function

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/21362139