SLAM receptors and SAP influence lymphocyte interactions, development and function (Q37349689)

19 August 2017

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SLAM receptors and SAP influence lymphocyte interactions, development and function (English)

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19 August 2017

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Pamela L Schwartzberg

1

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19 August 2017

Kristen L Mueller

2

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19 August 2017

Hai Qi

3

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19 August 2017

Jennifer L Cannons

4

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19 August 2017

1 January 2009

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Nature Reviews Immunology

19 August 2017

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19 August 2017

9

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19 August 2017

39-46

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19 August 2017

1

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The SLAM and SAP gene families control innate and adaptive immune responses.

19 August 2017

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Regulation of cellular and humoral immune responses by the SLAM and SAP families of molecules.

31 March 2020

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Immune regulation by SLAM family receptors and SAP-related adaptors

31 March 2020

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Regulation of NK cell activity by 2B4, NTB-A and CRACC.

31 March 2020

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SAP is required for generating long-term humoral immunity

31 March 2020

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SH2D1A regulates T-dependent humoral autoimmunity

31 March 2020

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Impaired humoral immunity in X-linked lymphoproliferative disease is associated with defective IL-10 production by CD4+ T cells

31 March 2020

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Selective generation of functional somatically mutated IgM+CD27+, but not Ig isotype-switched, memory B cells in X-linked lymphoproliferative disease

31 March 2020

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Defective B cell responses in the absence of SH2D1A

31 March 2020

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Cutting Edge: Signaling Lymphocytic Activation Molecule-Associated Protein Controls NKT Cell Functions

31 March 2020

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Regulation of NKT cell development by SAP, the protein defective in XLP

31 March 2020

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Defective NKT cell development in mice and humans lacking the adapter SAP, the X-linked lymphoproliferative syndrome gene product

31 March 2020

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SAP regulates T(H)2 differentiation and PKC-theta-mediated activation of NF-kappaB1

31 March 2020

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Altered lymphocyte responses and cytokine production in mice deficient in the X-linked lymphoproliferative disease gene SH2D1A/DSHP/SAP

31 March 2020

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Genetic evidence linking SAP, the X-linked lymphoproliferative gene product, to Src-related kinase FynT in T(H)2 cytokine regulation.

31 March 2020

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SAP controls T cell responses to virus and terminal differentiation of TH2 cells.

31 March 2020

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The X-linked lymphoproliferative-disease gene product SAP regulates signals induced through the co-receptor SLAM

31 March 2020

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The role of SAP and the SLAM family in autoimmunity

31 March 2020

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SAP couples Fyn to SLAM immune receptors

31 March 2020

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Regulation of SLAM-mediated signal transduction by SAP, the X-linked lymphoproliferative gene product

31 March 2020

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Binding of SAP SH2 domain to FynT SH3 domain reveals a novel mechanism of receptor signalling in immune regulation

31 March 2020

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Control of T lymphocyte signaling by Ly108, a signaling lymphocytic activation molecule family receptor implicated in autoimmunity

31 March 2020

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The X-linked lymphoproliferative disease gene product SAP associates with PAK-interacting exchange factor and participates in T cell activation

31 March 2020

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SAP regulates T cell-mediated help for humoral immunity by a mechanism distinct from cytokine regulation

31 March 2020

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SAP regulation of follicular helper CD4 T cell development and humoral immunity is independent of SLAM and Fyn kinase.

31 March 2020

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SAP expression in T cells, not in B cells, is required for humoral immunity

31 March 2020

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Signalling through TEC kinases regulates conventional versus innate CD8(+) T-cell development

31 March 2020

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The Src family tyrosine kinase Fyn regulates natural killer T cell development

31 March 2020

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Signaling for NKT cell development: the SAP-FynT connection

31 March 2020

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Ly9 (CD229)-deficient mice exhibit T cell defects yet do not share several phenotypic characteristics associated with SLAM- and SAP-deficient mice.

31 March 2020

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Homotypic interactions mediated by Slamf1 and Slamf6 receptors control NKT cell lineage development

31 March 2020

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The cell surface receptor SLAM controls T cell and macrophage functions

31 March 2020

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T cell immune reconstitution after allogeneic bone marrow transplantation in bare lymphocyte syndrome

31 March 2020

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Thymocyte-thymocyte interaction for efficient positive selection and maturation of CD4 T cells.

31 March 2020

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An alternate pathway for CD4 T cell development: thymocyte-expressed MHC class II selects a distinct T cell population

31 March 2020

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The SLAM-associated protein signaling pathway is required for development of CD4+ T cells selected by homotypic thymocyte interaction

31 March 2020

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The Tec family tyrosine kinases Itk and Rlk regulate the development of conventional CD8+ T cells.

31 March 2020

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Altered development of CD8+ T cell lineages in mice deficient for the Tec kinases Itk and Rlk.

31 March 2020

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ITK and IL-15 support two distinct subsets of CD8+ T cells

31 March 2020

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Memory phenotype CD8+ T cells with innate function selectively develop in the absence of active Itk.

31 March 2020

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Requirements for selection of conventional and innate T lymphocyte lineages

31 March 2020

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Differential requirement for the SAP-Fyn interaction during NK T cell development and function

31 March 2020

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Germinal-center organization and cellular dynamics

31 March 2020

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Visualization of specific B and T lymphocyte interactions in the lymph node.

31 March 2020

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Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells

31 March 2020

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Making friends in out-of-the-way places: how cells of the immune system get together and how they conduct their business as revealed by intravital imaging

31 March 2020

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T follicular helper (TFH) cells in normal and dysregulated immune responses

31 March 2020

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A RING-type ubiquitin ligase family member required to repress follicular helper T cells and autoimmunity

31 March 2020

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Generation of T follicular helper cells is mediated by interleukin-21 but independent of T helper 1, 2, or 17 cell lineages

31 March 2020

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A fundamental role for interleukin-21 in the generation of T follicular helper cells

31 March 2020

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T follicular helper cells express a distinctive transcriptional profile, reflecting their role as non-Th1/Th2 effector cells that provide help for B cells

31 March 2020

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SAP is required for Th cell function and for immunity to influenza.

31 March 2020

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SAP enables T cells to help B cells by a mechanism distinct from Th cell programming or CD40 ligand regulation

31 March 2020

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Impaired Ig class switch in mice deficient for the X-linked lymphoproliferative disease gene Sap

31 March 2020

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A critical role for IL-21 in regulating immunoglobulin production

31 March 2020

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SAP-controlled T-B cell interactions underlie germinal centre formation

31 March 2020

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B cells alter the phenotype and function of follicular-homing CXCR5+ T cells

31 March 2020

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NTB-A receptor crystal structure: insights into homophilic interactions in the signaling lymphocytic activation molecule receptor family

31 March 2020

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Structure of CD84 provides insight into SLAM family function

31 March 2020

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Platelet aggregation induces platelet aggregate stability via SLAM family receptor signaling

31 March 2020

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SLAM-associated protein deficiency causes imbalanced early signal transduction and blocks downstream activation in T cells from X-linked lymphoproliferative disease patients

31 March 2020

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Multifocal structure of the T cell - dendritic cell synapse

31 March 2020

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XIAP deficiency in humans causes an X-linked lymphoproliferative syndrome

31 March 2020

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Cutting edge: the SLAM family receptor Ly108 controls T cell and neutrophil functions.

31 March 2020

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CDw150 associates with src-homology 2-containing inositol phosphatase and modulates CD95-mediated apoptosis

31 March 2020

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PubMed

https://pubmed.ncbi.nlm.nih.gov/19079134

12 December 2020

inferred from PubMed ID database lookup

Cutting edge: NKT cell development is selectively impaired in Fyn- deficient mice.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19079134

12 December 2020

inferred from PubMed ID database lookup

Bone marrow transplantation in major histocompatibility complex class II deficiency: a single-center study of 19 patients

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19079134

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1038/NRI2456

1 reference

release_okvm4ffw7nfvleiyo3l2u4ixau

19 August 2017

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/okvm4ffw7nfvleiyo3l2u4ixau

24 November 2022

mapped directly with Wikidata item

1 reference