Characterization and in vivo pharmacological rescue of a Wnt2-Gata6 pathway required for cardiac inflow tract development (Q24610934)

Catenin (cadherin associated protein), beta 1

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

1 reference

Ying Tian

1

0 references

Lijun Yuan

2

0 references

Ashley M Goss

3

0 references

Tao Wang

4

0 references

Jifu Yang

5

0 references

John J Lepore

6

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Diane Zhou

7

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Robert J Schwartz

8

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Vickas Patel

9

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Ethan David Cohen

10

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Edward E Morrisey

Loss of both GATA4 and GATA6 blocks cardiac myocyte differentiation and results in acardia in mice

11

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language of work or name

English

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publication date

16 February 2010

0 references

published in

Developmental Cell

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volume

18

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issue

2

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page(s)

275-87

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cites work

1 reference

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Mutations at the SALL4 locus on chromosome 20 result in a range of clinically overlapping phenotypes, including Okihiro syndrome, Holt-Oram syndrome, acro-renal-ocular syndrome, and patients previously reported to represent thalidomide embryopathy

7 April 2017

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A molecular mechanism for the effect of lithium on development

7 April 2017

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Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut

7 April 2017

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Sox17 is essential for the specification of cardiac mesoderm in embryonic stem cells

7 April 2017

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A Sall4 mutant mouse model useful for studying the role of Sall4 in early embryonic development and organogenesis

7 April 2017

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Wnt2 is a direct downstream target of GATA6 during early cardiogenesis

7 April 2017

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7 April 2017

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Cooperative and antagonistic interactions between Sall4 and Tbx5 pattern the mouse limb and heart

7 April 2017

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Atrioventricular cushion transformation is mediated by ALK2 in the developing mouse heart

7 April 2017

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Morphogenesis of the right ventricle requires myocardial expression of Gata4

7 April 2017

1 reference

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Foxp1 regulates cardiac outflow tract, endocardial cushion morphogenesis and myocyte proliferation and maturation

7 April 2017

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Canonical WNT signaling promotes mammary placode development and is essential for initiation of mammary gland morphogenesis

7 April 2017

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Isl1 identifies a cardiac progenitor population that proliferates prior to differentiation and contributes a majority of cells to the heart

7 April 2017

1 reference

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Dishevelled 2 is essential for cardiac outflow tract development, somite segmentation and neural tube closure

7 April 2017

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Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development

7 April 2017

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Inhibition of Wnt activity induces heart formation from posterior mesoderm

7 April 2017

1 reference

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GATA-5: a transcriptional activator expressed in a novel temporally and spatially-restricted pattern during embryonic development

7 April 2017

1 reference

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Msx1 and Msx2 regulate survival of secondary heart field precursors and post-migratory proliferation of cardiac neural crest in the outflow tract

7 April 2017

1 reference

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Beta-catenin directly regulates Islet1 expression in cardiovascular progenitors and is required for multiple aspects of cardiogenesis

7 April 2017

1 reference

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Canonical Wnt signaling functions in second heart field to promote right ventricular growth

7 April 2017

1 reference

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Pitx2 regulates cardiac left-right asymmetry by patterning second cardiac lineage-derived myocardium

7 April 2017

1 reference

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Endocardial and epicardial derived FGF signals regulate myocardial proliferation and differentiation in vivo

7 April 2017

1 reference

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Expression pattern of mouse sFRP-1 and mWnt-8 gene during heart morphogenesis

7 April 2017

1 reference

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Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation

7 April 2017

1 reference

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Targeted disruption of the Wnt2 gene results in placentation defects

7 April 2017

1 reference

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Echocardiographic assessment of global left ventricular function in mice

7 April 2017

1 reference

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GATA4 is a direct transcriptional activator of cyclin D2 and Cdk4 and is required for cardiomyocyte proliferation in anterior heart field-derived myocardium.

27 September 2017

1 reference

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The renewal and differentiation of Isl1+ cardiovascular progenitors are controlled by a Wnt/beta-catenin pathway

27 September 2017

1 reference

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Atrial myocardium derives from the posterior region of the second heart field, which acquires left-right identity as Pitx2c is expressed.

27 September 2017

1 reference

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Distinct roles of Wnt/beta-catenin and Bmp signaling during early cardiogenesis

27 September 2017

1 reference

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Wnt/beta-catenin signaling promotes expansion of Isl-1-positive cardiac progenitor cells through regulation of FGF signaling

27 September 2017

1 reference

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Canonical Wnt signaling is a positive regulator of mammalian cardiac progenitors

27 September 2017

1 reference

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Biphasic role for Wnt/beta-catenin signaling in cardiac specification in zebrafish and embryonic stem cells

27 September 2017

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An essential role for Notch in neural crest during cardiovascular development and smooth muscle differentiation.

27 September 2017

1 reference

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A spatiotemporal evaluation of the contribution of the dorsal mesenchymal protrusion to cardiac development

27 September 2017

1 reference

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Development and structures of the venous pole of the heart

27 September 2017

1 reference

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Heart induction by Wnt antagonists depends on the homeodomain transcription factor Hex.

27 September 2017

1 reference

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Wnt11 facilitates embryonic stem cell differentiation to Nkx2.5-positive cardiomyocytes

27 September 2017

1 reference

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A Wnt- and beta -catenin-dependent pathway for mammalian cardiac myogenesis

27 September 2017

1 reference

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Wnt-11 activation of a non-canonical Wnt signalling pathway is required for cardiogenesis

27 September 2017

1 reference

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The molecular basis of congenital cardiac disease

27 September 2017

1 reference

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Wnt antagonism initiates cardiogenesis in Xenopus laevis

27 September 2017

1 reference

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Mechanisms involved in valvuloseptal endocardial cushion formation in early cardiogenesis: roles of transforming growth factor (TGF)-beta and bone morphogenetic protein (BMP).

27 September 2017

1 reference

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Anatomical-embryological correlates in atrioventricular septal defect

27 September 2017

1 reference

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A Gata6-Wnt pathway required for epithelial stem cell development and airway regeneration.

27 September 2017

1 reference

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GATA transcription factors integrate Wnt signalling during heart development.

30 May 2018

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Regulation of Akt mRNA and protein levels by glycogen synthase kinase-3beta in adrenal chromaffin cells: effects of LiCl and SB216763.

28 November 2018

1 reference

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Islet 1 is expressed in distinct cardiovascular lineages, including pacemaker and coronary vascular cells

28 November 2018

1 reference

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Formation of the Venous Pole of the Heart From an Nkx2-5-Negative Precursor Population Requires Tbx18

28 November 2018

1 reference

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Activation of Notch1 signaling in cardiogenic mesoderm induces abnormal heart morphogenesis in mouse

28 November 2018

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sall4 acts downstream of tbx5 and is required for pectoral fin outgrowth

28 November 2018

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Molecular markers of cardiac endocardial cushion development.

28 November 2018

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Wnt7b regulates mesenchymal proliferation and vascular development in the lung.

28 November 2018

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Embryonic expression of an Nkx2-5/Cre gene using ROSA26 reporter mice.

28 November 2018

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Direct activation of a GATA6 cardiac enhancer by Nkx2.5: evidence for a reinforcing regulatory network of Nkx2.5 and GATA transcription factors in the developing heart.

28 November 2018

1 reference

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WNT11 promotes cardiac tissue formation of early mesoderm.

28 November 2018

1 reference

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GATA-4 activates transcription via two novel domains that are conserved within the GATA-4/5/6 subfamily

28 November 2018

1 reference

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Morphine antinociception is mediated through a LiCl-sensitive, IP3-restorable pathway

28 November 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/20159597

12 December 2020

inferred from PubMed ID database lookup

Atrial development in the human heart: an immunohistochemical study with emphasis on the role of mesenchymal tissues

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20159597

12 December 2020

inferred from PubMed ID database lookup

Isl1 expression at the venous pole identifies a novel role for the second heart field in cardiac development

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20159597

12 December 2020

inferred from PubMed ID database lookup

Identifiers

DOI

10.1016/J.DEVCEL.2010.01.008

1 reference

release_4yeweiaavzd4ddattfz4mk33ni

3887297

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/4yeweiaavzd4ddattfz4mk33ni

24 November 2022

mapped directly with Wikidata item

3887297

1 reference

1 reference

1 reference