Catenin (cadherin associated protein), beta 1 (Q14902827)

Armadillo-like helical

1 reference

stated in

Armadillo-type fold

1 reference

stated in

inferred from GOA cell component → membrane

membrane protein

1 reference

based on heuristic

armadillo domain proteins

1 reference

based on heuristic

inferred from protein domain or family

Armadillo domain, protein family

1 reference

based on heuristic

inferred from protein domain or family

1 reference

25 May 2022

1 reference

25 May 2022

DNA-binding transcription factor activity

1 reference

8 April 2019

Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

protein phosphatase binding

3 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

Intracellular substrates of brain-enriched receptor protein tyrosine phosphatase rho (RPTPρ/PTPRT)

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

transcription factor binding

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

6 references

21 June 2018

Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Expression and cell membrane localization of catenins during mouse preimplantation development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Ksp-cadherin is a functional cell-cell adhesion molecule related to LI-cadherin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Beta-catenin is temporally regulated during normal liver development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

The cadherin cytoplasmic domain is unstructured in the absence of beta-catenin. A possible mechanism for regulating cadherin turnover

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

3 references

histone methyltransferase binding

1 reference

8 April 2019

Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

15 references

8 April 2019

Wnt/β-catenin signalling regulates Sox17 expression and is essential for organizer and endoderm formation in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

A regulatory pathway involving Notch1/beta-catenin/Isl1 determines cardiac progenitor cell fate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Wnt signalling induces maturation of Paneth cells in intestinal crypts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Characterization and in vivo pharmacological rescue of a Wnt2-Gata6 pathway required for cardiac inflow tract development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Brn-2 expression controls melanoma proliferation and is directly regulated by beta-catenin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Wnt signaling regulates smooth muscle precursor development in the mouse lung via a tenascin C/PDGFR pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Canonical Wnt9b signaling balances progenitor cell expansion and differentiation during kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

CCN1/Cyr61 is regulated by the canonical Wnt signal and plays an important role in Wnt3A-induced osteoblast differentiation of mesenchymal stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Modulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

55 references

8 April 2019

Coxsackievirus and adenovirus receptor (CAR) mediates atrioventricular-node function and connexin 45 localization in the murine heart

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

alphaT-catenin: a novel tissue-specific beta-catenin-binding protein mediating strong cell-cell adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

ICAT inhibits beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

The TRPV4 channel contributes to intercellular junction formation in keratinocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Human scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coli

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

The mammalian homologue of the Caenorhabditis elegans polarity protein PAR-6 is a binding partner for the Rho GTPases Cdc42 and Rac1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

MAGI1 recruits Dll1 to cadherin-based adherens junctions and stabilizes it on the cell surface

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Sox17 modulates Wnt3A/beta-catenin-mediated transcriptional activation of the Lef-1 promoter.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Scribble interacts with beta-catenin to localize synaptic vesicles to synapses

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Sox2 induction by FGF and FGFR2 activating mutations inhibits Wnt signaling and osteoblast differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Substitution of a glycogen synthase kinase-3beta phosphorylation site in presenilin 1 separates presenilin function from beta-catenin signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Protein kinase CKII regulates the interaction of beta-catenin with alpha-catenin and its protein stability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

T-cell factor 4N (TCF-4N), a novel isoform of mouse TCF-4, synergizes with beta-catenin to coactivate C/EBPalpha and steroidogenic factor 1 transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Functional interaction of an axin homolog, conductin, with beta-catenin, APC, and GSK3beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

A unique and specific interaction between alphaT-catenin and plakophilin-2 in the area composita, the mixed-type junctional structure of cardiac intercalated discs

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Mammalian formin-1 participates in adherens junctions and polymerization of linear actin cables

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Functional domains of axin. Importance of the C terminus as an oligomerization domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

The KIF3 motor transports N-cadherin and organizes the developing neuroepithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Role of a BCL9-related beta-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Ozz-E3, a muscle-specific ubiquitin ligase, regulates beta-catenin degradation during myogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Arginine methyltransferase CARM1/PRMT4 regulates endochondral ossification

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

NF2deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Deficient E-cadherin adhesion in C57BL/6J-Min/+ mice is associated with increased tyrosine kinase activity and RhoA-dependent actomyosin contractility

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

SUMOylation target sites at the C terminus protect Axin from ubiquitination and confer protein stability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Hippo pathway inhibits Wnt signaling to restrain cardiomyocyte proliferation and heart size

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Cooperative control via lymphoid enhancer factor 1/T cell factor 3 and estrogen receptor-alpha for uterine gene regulation by estrogen

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

mrhl RNA, a long noncoding RNA, negatively regulates Wnt signaling through its protein partner Ddx5/p68 in mouse spermatogonial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

The PDZ protein tax-interacting protein-1 inhibits beta-catenin transcriptional activity and growth of colorectal cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

alpha3beta1 integrin-CD151, a component of the cadherin-catenin complex, regulates PTPmu expression and cell-cell adhesion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Mechanism of phosphorylation-dependent binding of APC to beta-catenin and its role in beta-catenin degradation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Intestinal tumorigenesis initiated by dedifferentiation and acquisition of stem-cell-like properties

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

TGIF governs a feed-forward network that empowers Wnt signaling to drive mammary tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Ezrin-mediated apical integrity is required for intestinal homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Mutant huntingtin-impaired degradation of beta-catenin causes neurotoxicity in Huntington's disease

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

A GSK3-binding peptide from FRAT1 selectively inhibits the GSK3-catalysed phosphorylation of axin and beta-catenin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Structure of the Dimerization and β-Catenin- Binding Region of α-Catenin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Identification of a novel beta-catenin-interacting protein

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

ICAT inhibits beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Axin negatively affects tau phosphorylation by glycogen synthase kinase 3beta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

A specific domain in alpha-catenin mediates binding to beta-catenin or plakoglobin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Direct inhibition of GSK3beta by the phosphorylated cytoplasmic domain of LRP6 in Wnt/beta-catenin signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

The PDZ protein tax-interacting protein-1 inhibits beta-catenin transcriptional activity and growth of colorectal cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Nemo kinase phosphorylates β-catenin to promote ommatidial rotation and connects core PCP factors to E-cadherin-β-catenin.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Functional analysis of novel phosphorylation sites of CREB-binding protein using mass spectrometry and mammalian two-hybrid assays

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Thermodynamics of beta-catenin-ligand interactions: the roles of the N- and C-terminal tails in modulating binding affinity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Jmjd3 controls mesodermal and cardiovascular differentiation of embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

ICAT inhibits beta-catenin binding to Tcf/Lef-family transcription factors and the general coactivator p300 using independent structural modules

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6

IPI

protein kinase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

IPI

7 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Wnt4 overexpression disrupts normal testicular vasculature and inhibits testosterone synthesis by repressing steroidogenic factor 1/beta-catenin synergy

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

alpha-catenin binding

4 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

A polarized epithelium organized by beta- and alpha-catenin predates cadherin and metazoan origins

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

Protein kinase CKII regulates the interaction of beta-catenin with alpha-catenin and its protein stability

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

protein heterodimerization activity

1 reference

8 April 2019

Expression and cell membrane localization of catenins during mouse preimplantation development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

disordered domain specific binding

1 reference

8 April 2019

The cadherin cytoplasmic domain is unstructured in the absence of beta-catenin. A possible mechanism for regulating cadherin turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

ionotropic glutamate receptor binding

IPI

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

protein-containing complex binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

nitric-oxide synthase binding

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

5 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

Lhx2 regulates the timing of β-catenin-dependent cortical neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

Wnt4 overexpression disrupts normal testicular vasculature and inhibits testosterone synthesis by repressing steroidogenic factor 1/beta-catenin synergy

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

7 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Lhx2 regulates the timing of β-catenin-dependent cortical neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Wnt4 overexpression disrupts normal testicular vasculature and inhibits testosterone synthesis by repressing steroidogenic factor 1/beta-catenin synergy

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

protein C-terminus binding

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

transcription factor binding

3 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

estrogen receptor binding

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

transmembrane transporter binding

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

alpha-catenin binding

3 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

A polarized epithelium organized by beta- and alpha-catenin predates cadherin and metazoan origins

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Protein kinase CKII regulates the interaction of beta-catenin with alpha-catenin and its protein stability

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

9 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Lhx2 regulates the timing of β-catenin-dependent cortical neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Wnt4 overexpression disrupts normal testicular vasculature and inhibits testosterone synthesis by repressing steroidogenic factor 1/beta-catenin synergy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

protein phosphatase binding

IBA

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Intracellular substrates of brain-enriched receptor protein tyrosine phosphatase rho (RPTPρ/PTPRT)

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

IBA

alpha-catenin binding

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

A polarized epithelium organized by beta- and alpha-catenin predates cadherin and metazoan origins

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Protein kinase CKII regulates the interaction of beta-catenin with alpha-catenin and its protein stability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 references

8 April 2019

Domains of axin involved in protein-protein interactions, Wnt pathway inhibition, and intracellular localization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Expression and cell membrane localization of catenins during mouse preimplantation development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Ksp-cadherin is a functional cell-cell adhesion molecule related to LI-cadherin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Beta-catenin is temporally regulated during normal liver development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

The cadherin cytoplasmic domain is unstructured in the absence of beta-catenin. A possible mechanism for regulating cadherin turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

14 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Dynamic expression and nuclear accumulation of beta-catenin during the development of hair follicle-derived structures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Stabilization of beta-catenin in the mouse zygote leads to premature epithelial-mesenchymal transition in the epiblast

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Wnt-beta-catenin signaling initiates taste papilla development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Patched1 functions as a gatekeeper by promoting cell cycle progression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Role of a BCL9-related beta-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Wnt11 promotes osteoblast maturation and mineralization through R-spondin 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Nuclear-cytoplasmic shuttling of Axin regulates subcellular localization of beta-catenin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Expression of Tcf/Lef and sFrp and localization of beta-catenin in the developing mouse lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

7 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Prolyl isomerase Pin1 regulates neuronal differentiation via β-catenin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblasts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Regulation of Wnt signaling during adipogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

beta-catenin-TCF7L2 complex

10 references

8 April 2019

Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Sox9 plays multiple roles in the lung epithelium during branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

TCL1 participates in early embryonic development and is overexpressed in human seminomas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Overexpression of Sonic Hedgehog suppresses embryonic hair follicle morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Diverse roles of E-cadherin in the morphogenesis of the submandibular gland: insights into the formation of acinar and ductal structures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Grainyhead-like 2 regulates neural tube closure and adhesion molecule expression during neural fold fusion

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Milk secretion and ejection are impaired in the mammary gland of mice harboring a Cx43 mutant while expression and localization of tight and adherens junction proteins remain unchanged

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Nuclear localization of beta-catenin and loss of apical brush border actin in cystic tubules of bcl-2 -/- mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

POPX2 phosphatase regulates the KIF3 kinesin motor complex

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

bicellular tight junction

1 reference

8 April 2019

Distinct subdomain organization and molecular composition of a tight junction with adherens junction features

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

7 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Localization of the novel Xin protein to the adherens junction complex in cardiac and skeletal muscle during development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Adhesion protein VSIG1 is required for the proper differentiation of glandular gastric epithelia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

NF2deficiency promotes tumorigenesis and metastasis by destabilizing adherens junctions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Wnt/β-catenin signalling regulates Sox17 expression and is essential for organizer and endoderm formation in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

microtubule organizing center

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

perinuclear region of cytoplasm

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

40 references

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Transmembrane protein 64 reciprocally regulates osteoblast and adipocyte differentiation by modulating Wnt/β-catenin signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brain

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Prolyl isomerase Pin1 regulates neuronal differentiation via β-catenin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Wnt/beta-catenin signaling is sufficient and necessary for synovial joint formation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Wnt signalling induces maturation of Paneth cells in intestinal crypts

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

mrhl RNA, a long noncoding RNA, negatively regulates Wnt signaling through its protein partner Ddx5/p68 in mouse spermatogonial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Role of a BCL9-related beta-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Wnt11 promotes osteoblast maturation and mineralization through R-spondin 2

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

C3G regulates the size of the cerebral cortex neural precursor population

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

A critical role for sFRP proteins in maintaining caudal neural tube closure in mice via inhibition of BMP signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Colorectal cancer in mice genetically deficient in the mucin Muc2

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

beta-Catenin is required for specification of proximal/distal cell fate during lung morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

The PDZ protein tax-interacting protein-1 inhibits beta-catenin transcriptional activity and growth of colorectal cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

RSPO1/β-catenin signaling pathway regulates oogonia differentiation and entry into meiosis in the mouse fetal ovary

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Wnt-beta-catenin signaling initiates taste papilla development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Overexpression of TEAD-1 in transgenic mouse striated muscles produces a slower skeletal muscle contractile phenotype

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Dynamic expression and nuclear accumulation of beta-catenin during the development of hair follicle-derived structures

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Activation of the transcription factor GLI1 by WNT signaling underlies the role of SULFATASE 2 as a regulator of tissue regeneration

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Lef1 is required for the transition of Wnt signaling from mesenchymal to epithelial cells in the mouse embryonic mammary gland

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

The Wnt/beta-catenin pathway regulates Gli-mediated Myf5 expression during somitogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Foxf1 and Foxf2 control murine gut development by limiting mesenchymal Wnt signaling and promoting extracellular matrix production

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Expression of Tcf/Lef and sFrp and localization of beta-catenin in the developing mouse lung

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Patched1 functions as a gatekeeper by promoting cell cycle progression

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

A positive feedback loop involving Gcm1 and Fzd5 directs chorionic branching morphogenesis in the placenta

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

24 April 2018

Jmjd3 controls mesodermal and cardiovascular differentiation of embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

Expression of catenins during mouse embryonic development and in adult tissues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

Membrane localization of adenomatous polyposis coli protein at cellular protrusions: targeting sequences and regulation by beta-catenin

cell projection membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

The transitional junction: a new functional subcellular domain at the intercalated disc

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

Foxf1 and Foxf2 control murine gut development by limiting mesenchymal Wnt signaling and promoting extracellular matrix production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

Lamellipodium extension and cadherin adhesion: two cell responses to cadherin activation relying on distinct signalling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

LRRK2 functions as a Wnt signaling scaffold, bridging cytosolic proteins and membrane-localized LRP6

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

A unique and specific interaction between alphaT-catenin and plakophilin-2 in the area composita, the mixed-type junctional structure of cardiac intercalated discs

lateral plasma membrane

1 reference

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

transcription regulator complex

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

T-cell factor 4N (TCF-4N), a novel isoform of mouse TCF-4, synergizes with beta-catenin to coactivate C/EBPalpha and steroidogenic factor 1 transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

12 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Expression and cell membrane localization of catenins during mouse preimplantation development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Apc tumor suppressor gene is the "zonation-keeper" of mouse liver

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Mouse mammary epithelial cells express the Na-K-Cl cotransporter, NKCC1: characterization, localization, and involvement in ductal development and morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Sec24b selectively sorts Vangl2 to regulate planar cell polarity during neural tube closure

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

C3G regulates the size of the cerebral cortex neural precursor population

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Tissue, cellular and sub-cellular localization of the Vangl2 protein during embryonic development: effect of the Lp mutation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Desmocollin 3 is required for pre-implantation development of the mouse embryo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

4 references

8 April 2019

Shroom regulates epithelial cell shape via the apical positioning of an actomyosin network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Loss of cell polarity causes severe brain dysplasia in Lgl1 knockout mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Tumor suppressor Nf2 limits expansion of the neural progenitor pool by inhibiting Yap/Taz transcriptional coactivators

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

The hyh mutation uncovers roles for alpha Snap in apical protein localization and control of neural cell fate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

apical junction complex

3 references

8 April 2019

Shroom regulates epithelial cell shape via the apical positioning of an actomyosin network

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Distinct subdomain organization and molecular composition of a tight junction with adherens junction features

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Shroom2, a myosin-VIIa- and actin-binding protein, directly interacts with ZO-1 at tight junctions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

beta-catenin destruction complex

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Functional domains of axin. Importance of the C terminus as an oligomerization domain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

Scrib-APC-beta-catenin complex

1 reference

8 April 2019

Human scribble, a novel tumor suppressor identified as a target of high-risk HPV E6 for ubiquitin-mediated degradation, interacts with adenomatous polyposis coli

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

Flotillin microdomains stabilize cadherins at cell-cell junctions

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

basolateral plasma membrane

9 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Foxj1 is required for apical localization of ezrin in airway epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

The small GTPase Rac1 regulates auditory hair cell morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Milk secretion and ejection are impaired in the mammary gland of mice harboring a Cx43 mutant while expression and localization of tight and adherens junction proteins remain unchanged

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Nuclear localization of beta-catenin and loss of apical brush border actin in cystic tubules of bcl-2 -/- mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

beta-Catenin is required for specification of proximal/distal cell fate during lung morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Haploinsufficiency of Krüppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

intracellular anatomical structure

3 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

The cohesin SMC3 is a target the for beta-catenin/TCF4 transactivation pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

The cadherin cytoplasmic domain is unstructured in the absence of beta-catenin. A possible mechanism for regulating cadherin turnover

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

Expression and cell membrane localization of catenins during mouse preimplantation development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

beta-catenin-TCF complex

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

13 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Dynamic expression and nuclear accumulation of beta-catenin during the development of hair follicle-derived structures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Protein kinase CKII regulates the interaction of beta-catenin with alpha-catenin and its protein stability

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Forkhead box A1 regulates prostate ductal morphogenesis and promotes epithelial cell maturation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Lamellipodium extension and cadherin adhesion: two cell responses to cadherin activation relying on distinct signalling pathways

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

RSPO1/β-catenin signaling pathway regulates oogonia differentiation and entry into meiosis in the mouse fetal ovary

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Expression of catenins during mouse embryonic development and in adult tissues

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Regulation of the SHP-2 tyrosine phosphatase by a novel cholesterol- and cell confluence-dependent mechanism

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Regulation of Wnt signaling during adipogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Bardet-Biedl syndrome 3 (Bbs3) knockout mouse model reveals common BBS-associated phenotypes and Bbs3 unique phenotypes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Hex homeobox gene controls the transition of the endoderm to a pseudostratified, cell emergent epithelium for liver bud development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Dlg5 regulates dendritic spine formation and synaptogenesis by controlling subcellular N-cadherin localization.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

41 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Lhx2 regulates the timing of β-catenin-dependent cortical neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Transmembrane protein 64 reciprocally regulates osteoblast and adipocyte differentiation by modulating Wnt/β-catenin signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Prolyl isomerase Pin1 regulates neuronal differentiation via β-catenin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Notch inhibition induces mitotically generated hair cells in mammalian cochleae via activating the Wnt pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Wnt-beta-catenin signaling initiates taste papilla development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

The Wnt/beta-catenin pathway regulates Gli-mediated Myf5 expression during somitogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

beta-Catenin is required for specification of proximal/distal cell fate during lung morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Expression of Tcf/Lef and sFrp and localization of beta-catenin in the developing mouse lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Regulation of spontaneous intestinal tumorigenesis through the adaptor protein MyD88

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

A positive feedback loop involving Gcm1 and Fzd5 directs chorionic branching morphogenesis in the placenta

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Unique mechanisms of growth regulation and tumor suppression upon Apc inactivation in the pancreas

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Colorectal cancer in mice genetically deficient in the mucin Muc2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Role of a BCL9-related beta-catenin-binding protein, B9L, in tumorigenesis induced by aberrant activation of Wnt signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Wnt11 promotes osteoblast maturation and mineralization through R-spondin 2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Foxf1 and Foxf2 control murine gut development by limiting mesenchymal Wnt signaling and promoting extracellular matrix production

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

RSPO1/β-catenin signaling pathway regulates oogonia differentiation and entry into meiosis in the mouse fetal ovary

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Wnt/beta-catenin signaling is sufficient and necessary for synovial joint formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Fgf10 dosage is critical for the amplification of epithelial cell progenitors and for the formation of multiple mesenchymal lineages during lung development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Dynamic expression and nuclear accumulation of beta-catenin during the development of hair follicle-derived structures

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Wnt signalling induces maturation of Paneth cells in intestinal crypts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Activation of the transcription factor GLI1 by WNT signaling underlies the role of SULFATASE 2 as a regulator of tissue regeneration

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Levels of mesenchymal FGFR2 signaling modulate smooth muscle progenitor cell commitment in the lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

A critical role for sFRP proteins in maintaining caudal neural tube closure in mice via inhibition of BMP signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Uncovering early response of gene regulatory networks in ESCs by systematic induction of transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

C3G regulates the size of the cerebral cortex neural precursor population

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Kruppel-like factor 5 controls villus formation and initiation of cytodifferentiation in the embryonic intestinal epithelium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

mrhl RNA, a long noncoding RNA, negatively regulates Wnt signaling through its protein partner Ddx5/p68 in mouse spermatogonial cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

The PDZ protein tax-interacting protein-1 inhibits beta-catenin transcriptional activity and growth of colorectal cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Patched1 functions as a gatekeeper by promoting cell cycle progression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Lef1 is required for the transition of Wnt signaling from mesenchymal to epithelial cells in the mouse embryonic mammary gland

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Overexpression of TEAD-1 in transgenic mouse striated muscles produces a slower skeletal muscle contractile phenotype

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Wnt7a activates the planar cell polarity pathway to drive the symmetric expansion of satellite stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Jmjd3 controls mesodermal and cardiovascular differentiation of embryonic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

transcription regulator complex

4 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

T-cell factor 4N (TCF-4N), a novel isoform of mouse TCF-4, synergizes with beta-catenin to coactivate C/EBPalpha and steroidogenic factor 1 transcription factors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

6 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brain

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Prolyl isomerase Pin1 regulates neuronal differentiation via β-catenin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Regulation of Wnt signaling during adipogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Wnt10b deficiency promotes coexpression of myogenic and adipogenic programs in myoblasts

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

8 references

21 June 2018

Regulation of cardiovascular development and integrity by the heart of glass-cerebral cavernous malformation protein pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Sox9 plays multiple roles in the lung epithelium during branching morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Nuclear localization of beta-catenin and loss of apical brush border actin in cystic tubules of bcl-2 -/- mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Milk secretion and ejection are impaired in the mammary gland of mice harboring a Cx43 mutant while expression and localization of tight and adherens junction proteins remain unchanged

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

TCL1 participates in early embryonic development and is overexpressed in human seminomas

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Grainyhead-like 2 regulates neural tube closure and adhesion molecule expression during neural fold fusion

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Overexpression of Sonic Hedgehog suppresses embryonic hair follicle morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Diverse roles of E-cadherin in the morphogenesis of the submandibular gland: insights into the formation of acinar and ductal structures

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

basolateral plasma membrane

8 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

The small GTPase Rac1 regulates auditory hair cell morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Nuclear localization of beta-catenin and loss of apical brush border actin in cystic tubules of bcl-2 -/- mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Foxj1 is required for apical localization of ezrin in airway epithelial cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Milk secretion and ejection are impaired in the mammary gland of mice harboring a Cx43 mutant while expression and localization of tight and adherens junction proteins remain unchanged

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Haploinsufficiency of Krüppel-like factor 4 promotes adenomatous polyposis coli dependent intestinal tumorigenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Orpk mouse model of polycystic kidney disease reveals essential role of primary cilia in pancreatic tissue organization

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

beta-Catenin is required for specification of proximal/distal cell fate during lung morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

4 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

The cadherin cytoplasmic domain is unstructured in the absence of beta-catenin. A possible mechanism for regulating cadherin turnover

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Expression and cell membrane localization of catenins during mouse preimplantation development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

beta-catenin destruction complex

3 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Functional domains of axin. Importance of the C terminus as an oligomerization domain

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

protein-containing complex

1 reference

21 June 2018

Histone H1 recruitment by CHD8 is essential for suppression of the Wnt-β-catenin signaling pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

beta-catenin-TCF complex

3 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Two members of the Tcf family implicated in Wnt/beta-catenin signaling during embryogenesis in the mouse

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brain

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

intracellular anatomical structure

IC

1 reference

1 January 2018

The cohesin SMC3 is a target the for beta-catenin/TCF4 transactivation pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

6 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

The cadherin cytoplasmic domain is unstructured in the absence of beta-catenin. A possible mechanism for regulating cadherin turnover

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Expression and cell membrane localization of catenins during mouse preimplantation development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

The catenin/cadherin adhesion system is localized in synaptic junctions bordering transmitter release zones.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

The catenin/cadherin adhesion system is localized in synaptic junctions bordering transmitter release zones.

postsynaptic membrane

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

presynaptic active zone cytoplasmic component

1 reference

8 April 2019

The catenin/cadherin adhesion system is localized in synaptic junctions bordering transmitter release zones.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

postsynaptic density, intracellular component

1 reference

8 April 2019

The catenin/cadherin adhesion system is localized in synaptic junctions bordering transmitter release zones.

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

skeletal system development

biological process

1 reference

8 April 2019

Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

negative regulation of protein sumoylation

male genitalia development

1 reference

8 April 2019

Genetic interactions of the androgen and Wnt/beta-catenin pathways for the masculinization of external genitalia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

positive regulation of endothelial cell differentiation

1 reference

8 April 2019

Formation and differentiation of multiple mesenchymal lineages during lung development is regulated by beta-catenin signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

regulation of protein localization to cell surface

T cell differentiation in thymus

1 reference

8 April 2019

Loss of adenomatous polyposis coli gene function disrupts thymic development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

positive regulation of skeletal muscle tissue development

1 reference

8 April 2019

β-catenin is essential for efficient in vitro premyogenic mesoderm formation but can be partially compensated by retinoic acid signalling

Community Assessment of Community Annotation with Ontologies

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

regulation of centromeric sister chromatid cohesion

regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Antagonistic crosstalk of Wnt/beta-catenin/Bmp signaling within the Apical Ectodermal Ridge (AER) regulates interdigit formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

positive regulation of fibroblast growth factor receptor signaling pathway

Epicardial-myocardial signaling directing coronary vasculogenesis

mesenchyme development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

regulation of core promoter binding

1 reference

8 April 2019

Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

cranial skeletal system development

1 reference

8 April 2019

Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

Lack of beta-catenin affects mouse development at gastrulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

regulation of calcium ion import

lung cell differentiation

1 reference

8 April 2019

beta-Catenin promotes respiratory progenitor identity in mouse foregut

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

dorsal/ventral axis specification

1 reference

8 April 2019

Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

embryonic heart tube development

1 reference

8 April 2019

Formation and differentiation of multiple mesenchymal lineages during lung development is regulated by beta-catenin signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

Ectodermal Wnt3/beta-catenin signaling is required for the establishment and maintenance of the apical ectodermal ridge

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

Formation and differentiation of multiple mesenchymal lineages during lung development is regulated by beta-catenin signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

stem cell population maintenance

1 reference

8 April 2019

Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

cranial ganglion development

1 reference

8 April 2019

Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

Deletion of β-catenin impairs T cell development

T cell differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

negative regulation of chondrocyte differentiation

1 reference

8 April 2019

Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

embryonic brain development

1 reference

8 April 2019

Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

negative regulation of oligodendrocyte differentiation

1 reference

8 April 2019

HDAC1 and HDAC2 regulate oligodendrocyte differentiation by disrupting the beta-catenin-TCF interaction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

positive regulation of epithelial cell proliferation involved in prostate gland development

1 reference

8 April 2019

Activation of beta-catenin in prostate epithelium induces hyperplasias and squamous transdifferentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

central nervous system vasculogenesis

1 reference

8 April 2019

Canonical Wnt signaling regulates organ-specific assembly and differentiation of CNS vasculature

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

Tissue-specific requirements of beta-catenin in external genitalia development

genitalia morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

epicardium-derived cardiac vascular smooth muscle cell differentiation

1 reference

8 April 2019

Epicardial-myocardial signaling directing coronary vasculogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

morphogenesis of embryonic epithelium

1 reference

8 April 2019

The duality of beta-catenin function: a requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

cell population proliferation

1 reference

8 April 2019

Inducible Cre-mediated control of gene expression in the murine gastrointestinal tract: effect of loss of beta-catenin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

negative regulation of cell population proliferation

canonical Wnt signaling pathway involved in positive regulation of cardiac outflow tract cell proliferation

1 reference

8 April 2019

Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

regulation of apoptotic process

1 reference

8 April 2019

Antagonistic crosstalk of Wnt/beta-catenin/Bmp signaling within the Apical Ectodermal Ridge (AER) regulates interdigit formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

Tissue-specific requirements of beta-catenin in external genitalia development

renal system development

1 reference

1 January 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

regulation of transcription, DNA-templated

3 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

Wnt/beta-catenin signaling regulates nephron induction during mouse kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

regulation of histone demethylase activity (H3-K4 specific)

1 reference

8 April 2019

Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

Loss of adenomatous polyposis coli gene function disrupts thymic development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

osteoclast differentiation

1 reference

8 April 2019

Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis

1 reference

8 April 2019

Wnt/beta-catenin signaling regulates nephron induction during mouse kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

negative regulation of cell differentiation

embryonic skeletal limb joint morphogenesis

1 reference

8 April 2019

The zinc finger transcription factors Osr1 and Osr2 control synovial joint formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

negative regulation of apoptotic signaling pathway

3 references

8 April 2019

Inducible Cre-mediated control of gene expression in the murine gastrointestinal tract: effect of loss of beta-catenin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

WNT4/beta-catenin pathway maintains female germ cell survival by inhibiting activin betaB in the mouse fetal ovary

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

WNT4/beta-catenin pathway maintains female germ cell survival by inhibiting activin betaB in the mouse fetal ovary

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

coronary artery morphogenesis

1 reference

8 April 2019

Epicardial-myocardial signaling directing coronary vasculogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

embryonic digit morphogenesis

3 references

8 April 2019

Antagonistic crosstalk of Wnt/beta-catenin/Bmp signaling within the Apical Ectodermal Ridge (AER) regulates interdigit formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Genetic interaction between Wnt/beta-catenin and BMP receptor signaling during formation of the AER and the dorsal-ventral axis in the limb

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Antagonistic crosstalk of Wnt/beta-catenin/Bmp signaling within the Apical Ectodermal Ridge (AER) regulates interdigit formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

ventricular compact myocardium morphogenesis

1 reference

8 April 2019

Epicardial-myocardial signaling directing coronary vasculogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

in utero embryonic development

positive regulation of determination of dorsal identity

1 reference

8 April 2019

Protein encoded by the Axin(Fu) allele effectively down-regulates Wnt signaling but exerts a dominant negative effect on c-Jun N-terminal kinase signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

smooth muscle cell differentiation

1 reference

8 April 2019

Wnt signaling regulates smooth muscle precursor development in the mouse lung via a tenascin C/PDGFR pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

transcription, DNA-templated

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

positive regulation of DNA-templated transcription, initiation

1 reference

8 April 2019

Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

positive regulation of transcription, DNA-templated

11 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Gata3 acts downstream of beta-catenin signaling to prevent ectopic metanephric kidney induction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Wnt signaling regulates smooth muscle precursor development in the mouse lung via a tenascin C/PDGFR pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Modulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Wnt4 overexpression disrupts normal testicular vasculature and inhibits testosterone synthesis by repressing steroidogenic factor 1/beta-catenin synergy

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

The Wnt/beta-catenin pathway regulates Gli-mediated Myf5 expression during somitogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

regulation of centriole-centriole cohesion

branching involved in ureteric bud morphogenesis

1 reference

8 April 2019

Wnt/beta-catenin signaling regulates nephron induction during mouse kidney development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

protein localization to cell surface

regulation of myelination

1 reference

8 April 2019

Dysregulation of the Wnt pathway inhibits timely myelination and remyelination in the mammalian CNS

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

regulation of osteoclast differentiation

1 reference

8 April 2019

Essential role of beta-catenin in postnatal bone acquisition

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

lens morphogenesis in camera-type eye

1 reference

8 April 2019

The duality of beta-catenin function: a requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

fungiform papilla formation

1 reference

8 April 2019

Wnt-beta-catenin signaling initiates taste papilla development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

branching involved in blood vessel morphogenesis

metanephros morphogenesis

1 reference

8 April 2019

A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

Beta-catenin is essential for pancreatic acinar but not islet development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

positive regulation of MAPK cascade

1 reference

8 April 2019

APC inhibits ERK pathway activation and cellular proliferation induced by RAS

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

negative regulation of neuron death

1 reference

8 April 2019

Integration of β-catenin, sirtuin, and FOXO signaling protects from mutant huntingtin toxicity

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

chemical synaptic transmission

1 reference

8 April 2019

Role of β-Catenin in Synaptic Vesicle Localization and Presynaptic Assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

Tissue-specific requirements of beta-catenin in external genitalia development

animal organ development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

sympathetic ganglion development

1 reference

8 April 2019

Frizzled3 is required for neurogenesis and target innervation during sympathetic nervous system development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

regulation of nephron tubule epithelial cell differentiation

1 reference

8 April 2019

Gata3 acts downstream of beta-catenin signaling to prevent ectopic metanephric kidney induction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

beta-Catenin controls hair follicle morphogenesis and stem cell differentiation in the skin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

proximal/distal pattern formation

1 reference

8 April 2019

beta-Catenin is required for specification of proximal/distal cell fate during lung morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

renal inner medulla development

1 reference

8 April 2019

A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

positive regulation of branching involved in lung morphogenesis

1 reference

8 April 2019

An FGF-WNT gene regulatory network controls lung mesenchyme development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

embryonic foregut morphogenesis

1 reference

8 April 2019

Bmp4 is required for tracheal formation: a novel mouse model for tracheal agenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

renal outer medulla development

1 reference

8 April 2019

A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes

cell fate specification

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

Role of β-Catenin in Synaptic Vesicle Localization and Presynaptic Assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

regulation of euchromatin binding

1 reference

8 April 2019

Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

positive regulation of DNA-binding transcription factor activity

3 references

embryonic axis specification

1 reference

8 April 2019

The mouse Fused locus encodes Axin, an inhibitor of the Wnt signaling pathway that regulates embryonic axis formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

ASPM regulates Wnt signaling pathway activity in the developing brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

negative regulation of transcription by RNA polymerase II

1 reference

8 April 2019

Beta-catenin regulates differentiation of respiratory epithelial cells in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

regulation of smooth muscle cell proliferation

cardiac muscle cell proliferation

1 reference

8 April 2019

Epicardial-myocardial signaling directing coronary vasculogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

positive regulation of epithelial to mesenchymal transition

nervous system development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

WNT4/beta-catenin pathway maintains female germ cell survival by inhibiting activin betaB in the mouse fetal ovary

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

cellular response to indole-3-methanol

5 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

positive regulation of osteoblast differentiation

1 reference

8 April 2019

Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

Wnt/beta-catenin signaling regulates nephron induction during mouse kidney development

renal vesicle formation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

dorsal root ganglion development

1 reference

8 April 2019

Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

positive regulation of telomerase activity

1 reference

8 April 2019

Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

Depletion of canonical Wnt signaling components has a neuroprotective effect on midbrain dopaminergic neurons in an MPTP-induced mouse model of Parkinson's disease

neuron differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

regulation of gene expression

1 reference

8 April 2019

Increased β-catenin activity in the anterior neural plate induces ectopic mid-hindbrain characteristics

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

canonical Wnt signaling pathway

15 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Wnt signaling regulates smooth muscle precursor development in the mouse lung via a tenascin C/PDGFR pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

WNT4/beta-catenin pathway maintains female germ cell survival by inhibiting activin betaB in the mouse fetal ovary

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Sox2 induction by FGF and FGFR2 activating mutations inhibits Wnt signaling and osteoblast differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

A role for Wnt signalling in self-renewal of haematopoietic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

Increased β-catenin activity in the anterior neural plate induces ectopic mid-hindbrain characteristics

neural plate development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

Inducible Cre-mediated control of gene expression in the murine gastrointestinal tract: effect of loss of beta-catenin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

anterior/posterior axis specification

1 reference

8 April 2019

Requirement for beta-catenin in anterior-posterior axis formation in mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

regulation of epithelial cell differentiation

1 reference

8 April 2019

Activation of beta-catenin in prostate epithelium induces hyperplasias and squamous transdifferentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

adherens junction organization

1 reference

8 April 2019

Wnt/beta-catenin signaling is required for CNS, but not non-CNS, angiogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

dorsal/ventral pattern formation

1 reference

8 April 2019

Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalon

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

negative regulation of transcription, DNA-templated

4 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

beta-Catenin promotes respiratory progenitor identity in mouse foregut

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

embryonic forelimb morphogenesis

1 reference

8 April 2019

Wnt/beta-catenin signaling is sufficient and necessary for synovial joint formation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

Epicardial-myocardial signaling directing coronary vasculogenesis

mesenchyme morphogenesis

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

positive regulation of heparan sulfate proteoglycan biosynthetic process

glial cell fate determination

1 reference

8 April 2019

Persistent expression of stabilized beta-catenin delays maturation of radial glial cells into intermediate progenitors

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

regulation of T cell proliferation

1 reference

8 April 2019

Deletion of β-catenin impairs T cell development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

epithelial cell differentiation involved in prostate gland development

response to estradiol

1 reference

8 April 2019

Activation of beta-catenin in prostate epithelium induces hyperplasias and squamous transdifferentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

adherens junction assembly

negative regulation of osteoclast differentiation

1 reference

8 April 2019

Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

negative regulation of mitotic cell cycle, embryonic

1 reference

8 April 2019

Frizzled3 is required for neurogenesis and target innervation during sympathetic nervous system development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

endothelial tube morphogenesis

cellular response to growth factor stimulus

gastrulation with mouth forming second

1 reference

8 April 2019

Lack of beta-catenin affects mouse development at gastrulation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

cardiac vascular smooth muscle cell differentiation

1 reference

8 April 2019

Epicardial-myocardial signaling directing coronary vasculogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

Inactivation of the beta-catenin gene by Wnt1-Cre-mediated deletion results in dramatic brain malformation and failure of craniofacial development

hindbrain development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

positive regulation of telomere maintenance via telomerase

1 reference

8 April 2019

Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

canonical Wnt signaling pathway involved in positive regulation of epithelial to mesenchymal transition

positive regulation of epithelial cell differentiation

1 reference

8 April 2019

Beta-catenin regulates differentiation of respiratory epithelial cells in vivo

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

regulation of secondary heart field cardioblast proliferation

1 reference

8 April 2019

A regulatory pathway involving Notch1/beta-catenin/Isl1 determines cardiac progenitor cell fate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

endodermal cell fate commitment

1 reference

8 April 2019

Formation of multiple hearts in mice following deletion of beta-catenin in the embryonic endoderm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

positive regulation of gene expression

Wnt/beta-catenin signaling is required for CNS, but not non-CNS, angiogenesis

vasculature development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

regulation of cell population proliferation

3 references

8 April 2019

The stabilization of beta-catenin leads to impaired primordial germ cell development via aberrant cell cycle progression

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Tissue-specific requirements of beta-catenin in external genitalia development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

layer formation in cerebral cortex

1 reference

8 April 2019

Expression analysis of an evolutionarily conserved metallophosphodiesterase gene, Mpped1, in the normal and beta-catenin-deficient malformed dorsal telencephalon

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

Essential roles of mesenchyme-derived beta-catenin in mouse Müllerian duct morphogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

positive regulation of cell population proliferation

1 reference

8 April 2019

Wnt signaling regulates smooth muscle precursor development in the mouse lung via a tenascin C/PDGFR pathway

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

positive regulation of apoptotic process

positive regulation of I-kappaB kinase/NF-kappaB signaling

1 reference

8 April 2019

Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

synaptic vesicle transport

1 reference

8 April 2019

Role of β-Catenin in Synaptic Vesicle Localization and Presynaptic Assembly

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalon

cell fate determination

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

regulation of cell differentiation

1 reference

8 April 2019

A role for Wnt signalling in self-renewal of haematopoietic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

Wnt/beta-catenin signaling regulates nephron induction during mouse kidney development

nephron tubule formation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

Effects of canonical Wnt signaling on dorso-ventral specification of the mouse telencephalon

forebrain development

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

cell morphogenesis involved in differentiation

1 reference

8 April 2019

The duality of beta-catenin function: a requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

lung-associated mesenchyme development

1 reference

8 April 2019

An FGF-WNT gene regulatory network controls lung mesenchyme development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

epithelial tube branching involved in lung morphogenesis

1 reference

8 April 2019

Formation and differentiation of multiple mesenchymal lineages during lung development is regulated by beta-catenin signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

A role for Wnt signalling in self-renewal of haematopoietic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

positive regulation of transcription by RNA polymerase II

16 references

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

Lhx2 regulates the timing of β-catenin-dependent cortical neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

Brn-2 expression controls melanoma proliferation and is directly regulated by beta-catenin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brain

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

Wnt signalling induces maturation of Paneth cells in intestinal crypts

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

Pax3 functions at a nodal point in melanocyte stem cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

Characterization and in vivo pharmacological rescue of a Wnt2-Gata6 pathway required for cardiac inflow tract development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

A regulatory pathway involving Notch1/beta-catenin/Isl1 determines cardiac progenitor cell fate

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

The Wnt3a/β-catenin target gene Mesogenin1 controls the segmentation clock by activating a Notch signalling program

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

5 June 2018

The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

embryonic hindlimb morphogenesis

odontogenesis of dentin-containing tooth

1 reference

8 April 2019

Canonical Wnt signaling in differentiated osteoblasts controls osteoclast differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

canonical Wnt signaling pathway involved in midbrain dopaminergic neuron differentiation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

midbrain dopaminergic neuron differentiation

IC

1 reference

8 April 2019

Wnt antagonism of Shh facilitates midbrain floor plate neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

negative regulation of angiogenesis

1 reference

8 April 2019

Resveratrol-Induced Vascular Progenitor Differentiation towards Endothelial Lineage via MiR-21/Akt/β-Catenin Is Protective in Vessel Graft Models

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

regulation of timing of anagen

1 reference

8 April 2019

Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

negative regulation of oxidative stress-induced neuron death

1 reference

8 April 2019

A Wnt1 regulated Frizzled-1/β-Catenin signaling pathway as a candidate regulatory circuit controlling mesencephalic dopaminergic neuron-astrocyte crosstalk: Therapeutical relevance for neuron survival and neuroprotection

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

positive regulation of core promoter binding

3 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

The duality of beta-catenin function: a requirement in lens morphogenesis and signaling suppression of lens fate in periocular ectoderm

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

neuron projection extension

transcription by RNA polymerase II

1 reference

24 April 2018

Gene Ontology Consortium

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

Wnt signaling pathway

1 reference

8 April 2019

1 reference

8 April 2019

A role for Wnt signalling in self-renewal of haematopoietic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

Schwann cell proliferation

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

protein heterooligomerization

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

cellular response to mechanical stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

cellular response to insulin-like growth factor stimulus

1 reference

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

negative regulation of neurogenesis

1 reference

8 April 2019

Lhx2 regulates the timing of β-catenin-dependent cortical neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

positive regulation of neural precursor cell proliferation

1 reference

8 April 2019

Lhx2 regulates the timing of β-catenin-dependent cortical neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

positive regulation of neuron apoptotic process

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

canonical Wnt signaling pathway involved in negative regulation of apoptotic process

1 reference

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

negative regulation of transcription, DNA-templated

3 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

positive regulation of transcription, DNA-templated

10 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Gata3 acts downstream of beta-catenin signaling to prevent ectopic metanephric kidney induction

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Modulation of morphogenesis by noncanonical Wnt signaling requires ATF/CREB family-mediated transcriptional activation of TGFbeta2

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Canonical Wnt/beta-catenin signaling prevents osteoblasts from differentiating into chondrocytes

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Wnt signaling regulates smooth muscle precursor development in the mouse lung via a tenascin C/PDGFR pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Wnt4 overexpression disrupts normal testicular vasculature and inhibits testosterone synthesis by repressing steroidogenic factor 1/beta-catenin synergy

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

A functional link between Wnt signaling and SKP2-independent p27 turnover in mammary tumors

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Lymphoid enhancer factor-1 and beta-catenin inhibit Runx2-dependent transcriptional activation of the osteocalcin promoter

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

The Wnt/beta-catenin pathway regulates Gli-mediated Myf5 expression during somitogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Hippocampus development and generation of dentate gyrus granule cells is regulated by LEF1

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

positive regulation of transcription by RNA polymerase II

15 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Lhx2 regulates the timing of β-catenin-dependent cortical neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Brn-2 expression controls melanoma proliferation and is directly regulated by beta-catenin

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brain

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Wnt signalling induces maturation of Paneth cells in intestinal crypts

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Pax3 functions at a nodal point in melanocyte stem cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

The Wnt3a/β-catenin target gene Mesogenin1 controls the segmentation clock by activating a Notch signalling program

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Characterization and in vivo pharmacological rescue of a Wnt2-Gata6 pathway required for cardiac inflow tract development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

A regulatory pathway involving Notch1/beta-catenin/Isl1 determines cardiac progenitor cell fate

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

canonical Wnt signaling pathway

13 references

21 June 2018

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Reciprocal requirements for EDA/EDAR/NF-kappaB and Wnt/beta-catenin signaling pathways in hair follicle induction

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

A Wnt7b-dependent pathway regulates the orientation of epithelial cell division and establishes the cortico-medullary axis of the mammalian kidney

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Wnt signaling regulates smooth muscle precursor development in the mouse lung via a tenascin C/PDGFR pathway

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Wnt9a signaling is required for joint integrity and regulation of Ihh during chondrogenesis

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Wnt2/2b and beta-catenin signaling are necessary and sufficient to specify lung progenitors in the foregut

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

WNT4/beta-catenin pathway maintains female germ cell survival by inhibiting activin betaB in the mouse fetal ovary

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Sox2 induction by FGF and FGFR2 activating mutations inhibits Wnt signaling and osteoblast differentiation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

A role for Wnt signalling in self-renewal of haematopoietic stem cells

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Identification of a Wnt/Dvl/beta-Catenin --> Pitx2 pathway mediating cell-type-specific proliferation during development

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Beta-catenin-induced melanoma growth requires the downstream target Microphthalmia-associated transcription factor

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

21 June 2018

Kindlin-1 controls Wnt and TGF-β availability to regulate cutaneous stem cell proliferation

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

regulation of transcription, DNA-templated

negative regulation of epithelial cell differentiation

1 reference

14 February 2019

Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

positive regulation of molecular function

1 reference

8 April 2019

Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

positive regulation of transcription by RNA polymerase II

17 references

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Lhx2 regulates the timing of β-catenin-dependent cortical neurogenesis

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Brn-2 expression controls melanoma proliferation and is directly regulated by beta-catenin

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Wnt/β-catenin signaling regulates telomerase in stem cells and cancer cells

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

LEF1/beta-catenin complex regulates transcription of the Cav3.1 calcium channel gene (Cacna1g) in thalamic neurons of the adult brain

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Homeodomain-mediated beta-catenin-dependent switching events dictate cell-lineage determination

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Pax3 functions at a nodal point in melanocyte stem cell differentiation

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Wnt signalling induces maturation of Paneth cells in intestinal crypts

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Wnt/beta-catenin signaling acts upstream of N-myc, BMP4, and FGF signaling to regulate proximal-distal patterning in the lung

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Characterization and in vivo pharmacological rescue of a Wnt2-Gata6 pathway required for cardiac inflow tract development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

The Wnt3a/β-catenin target gene Mesogenin1 controls the segmentation clock by activating a Notch signalling program

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

The Wnt/beta-catenin pathway modulates vascular remodeling and specification by upregulating Dll4/Notch signaling

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

A regulatory pathway involving Notch1/beta-catenin/Isl1 determines cardiac progenitor cell fate

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

8 April 2019

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

positive regulation of epithelial cell proliferation

IBA

1 reference

14 February 2019

Cyclin D1 genetic heterozygosity regulates colonic epithelial cell differentiation and tumor number in ApcMin mice

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

protein polyubiquitination

1 reference

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

1 reference

8 April 2019

Tissue-specific requirements of beta-catenin in external genitalia development

http://www.ebi.ac.uk/QuickGO/annotations?geneProductId=UniProtKB:Q02248

proteasome-mediated ubiquitin-dependent protein catabolic process

1 reference

14 January 2019

http://www.ebi.ac.uk/QuickGO/annotations?protein=Q02248&geneProductId=UniProtKB:Q02248

1 reference

Identifiers

1 reference

20 March 2022

1 reference

20 March 2022

1 reference

25 May 2022

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016

1 reference

9 August 2016