Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function (Q24614867)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22143799%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

title

Myopathy caused by mammalian target of rapamycin complex 1 (mTORC1) inactivation is not reversed by restoring mitochondrial function (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22143799%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

1 reference

6

1 reference

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17 January 2020

Christoph Handschin

7

1 reference

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17 January 2020

Yann-Gaël Gangloff

11

1 reference

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17 January 2020

author name string

Klaas Romanino

1

1 reference

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17 January 2020

Laetitia Mazelin

2

1 reference

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17 January 2020

Verena Albert

3

1 reference

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17 January 2020

Agnès Conjard-Duplany

4

1 reference

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17 January 2020

Shuo Lin

5

1 reference

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17 January 2020

Francesco Zorzato

9

1 reference

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17 January 2020

Laurent Schaeffer

10

1 reference

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17 January 2020

Markus A Rüegg

12

1 reference

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17 January 2020

Pere Puigserver

8

1 reference

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17 January 2020

language of work or name

English

0 references

publication date

5 December 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22143799%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

17 January 2020

published in

1 reference

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17 January 2020

volume

108

1 reference

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17 January 2020

page(s)

20808-20813

1 reference

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17 January 2020

issue

51

1 reference

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Dual and pan-peroxisome proliferator-activated receptors (PPAR) co-agonism: the bezafibrate lessons

17 January 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251091

TOR signaling in growth and metabolism

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251091

Mechanisms controlling mitochondrial biogenesis and respiration through the thermogenic coactivator PGC-1

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251091

Skeletal muscle hypertrophy and atrophy signaling pathways

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251091

Transcriptional co-activator PGC-1 alpha drives the formation of slow-twitch muscle fibres

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251091

mTOR controls mitochondrial oxidative function through a YY1-PGC-1alpha transcriptional complex

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251091

Metabolic control through the PGC-1 family of transcription coactivators

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251091

Absence of S6K1 protects against age- and diet-induced obesity while enhancing insulin sensitivity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251091

Muscle inactivation of mTOR causes metabolic and dystrophin defects leading to severe myopathy

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251091

Retracted: Increased muscle PGC-1α expression protects from sarcopenia and metabolic disease during aging

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251091

Skeletal muscle-specific ablation of raptor, but not of rictor, causes metabolic changes and results in muscle dystrophy

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251091

RETRACTED: Activation of the PPAR/PGC-1alpha pathway prevents a bioenergetic deficit and effectively improves a mitochondrial myopathy phenotype

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251091

Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1alpha transcription coactivator.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251091

PGC-1alpha regulates the neuromuscular junction program and ameliorates Duchenne muscular dystrophy.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251091

Lack of myostatin results in excessive muscle growth but impaired force generation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251091

PGC-1alpha protects skeletal muscle from atrophy by suppressing FoxO3 action and atrophy-specific gene transcription

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251091

Invited review: intracellular signaling in contracting skeletal muscle

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3251091

A role for the transcriptional coactivator PGC-1alpha in muscle refueling.

27 September 2017

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111448109

Activation of peroxisome proliferator-activated receptor pathway stimulates the mitochondrial respiratory chain and can correct deficiencies in patients' cells lacking its components.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111448109

Autophagy is required to maintain muscle mass.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111448109

Autophagy is defective in collagen VI muscular dystrophies and its reactivation rescues myofiber degeneration

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.1111448109

Skeletal muscle fiber-type switching, exercise intolerance, and myopathy in PGC-1alpha muscle-specific knock-out animals

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22143799

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The role of protein kinase B/Akt in insulin-induced inactivation of phosphorylase in rat hepatocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22143799

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1111448109

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22143799%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

ADS bibcode

2011PNAS..10820808R

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22143799%20AND%20SRC:MED&resulttype=core&format=json

17 January 2020

2 references