Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1alpha transcription coactivator. (Q40122836)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17554339%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

title

Akt/PKB regulates hepatic metabolism by directly inhibiting PGC-1alpha transcription coactivator (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17554339%20AND%20SRC:MED&resulttype=core&format=json

AKT serine/threonine kinase 1

31 December 2019

main subject

1 reference

identical protein binding

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Morris J. Birnbaum

4

1 reference

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31 December 2019

author name string

Xinghai Li

1

1 reference

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31 December 2019

Bobby Monks

2

1 reference

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31 December 2019

Qingyuan Ge

3

1 reference

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31 December 2019

language of work or name

English

0 references

publication date

6 June 2007

1 reference

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31 December 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17554339%20AND%20SRC:MED&resulttype=core&format=json

31 December 2019

volume

447

1 reference

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31 December 2019

page(s)

1012-1016

1 reference

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31 December 2019

issue

7147

1 reference

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https://scigraph.springernature.com/pub.10.1038/nature05861

31 December 2019

exact match

0 references

cites work

The Cellular Fate of Glucose and Its Relevance in Type 2 Diabetes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Banting lecture 2001: dysregulation of fatty acid metabolism in the etiology of type 2 diabetes

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Global and societal implications of the diabetes epidemic

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Contribution of hepatic de novo lipogenesis and reesterification of plasma non esterified fatty acids to plasma triglyceride synthesis during non-alcoholic fatty liver disease

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Mechanisms linking obesity with cardiovascular disease

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Preventing cardiovascular disease and diabetes: a call to action from the American Diabetes Association and the American Heart Association

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Metabolic control through the PGC-1 family of transcription coactivators

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Insulin-regulated hepatic gluconeogenesis through FOXO1-PGC-1alpha interaction

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

FoxO proteins in insulin action and metabolism

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Activation of protein kinase B/Akt is sufficient to repress the glucocorticoid and cAMP induction of phosphoenolpyruvate carboxykinase gene.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Insulin resistance and a diabetes mellitus-like syndrome in mice lacking the protein kinase Akt2 (PKB beta)

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Expression of a constitutively active Akt Ser/Thr kinase in 3T3-L1 adipocytes stimulates glucose uptake and glucose transporter 4 translocation

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Potential role of protein kinase B in insulin-induced glucose transport, glycogen synthesis, and protein synthesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Advances in protein kinase B signalling: AKTion on multiple fronts

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Novel concepts in insulin regulation of hepatic gluconeogenesis

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

The forkhead transcription factor Foxo1 (Fkhr) confers insulin sensitivity onto glucose-6-phosphatase expression

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

The nuclear bile acid receptor FXR is activated by PGC-1alpha in a ligand-dependent manner

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

The transcriptional coactivator PGC-1 regulates the expression and activity of the orphan nuclear receptor estrogen-related receptor alpha (ERRalpha).

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Peroxisome proliferator-activated receptor coactivator-1alpha (PGC-1alpha) coactivates the cardiac-enriched nuclear receptors estrogen-related receptor-alpha and -gamma. Identification of novel leucine-rich interaction motif within PGC-1alpha

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Exercise induces transient transcriptional activation of the PGC-1alpha gene in human skeletal muscle

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Peroxisome proliferator-activated receptor-gamma coactivator 1 alpha (PGC-1 alpha): transcriptional coactivator and metabolic regulator

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Control of hepatic gluconeogenesis through the transcriptional coactivator PGC-1

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Peptide and protein library screening defines optimal substrate motifs for AKT/PKB.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Hepatic Akt activation induces marked hypoglycemia, hepatomegaly, and hypertriglyceridemia with sterol regulatory element binding protein involvement

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Gluconeogenesis: re-evaluating the FOXO1-PGC-1alpha connection

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Protein phosphatase 2A and its B56 regulatory subunit inhibit Wnt signaling in Xenopus

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Lipin 1 is an inducible amplifier of the hepatic PGC-1alpha/PPARalpha regulatory pathway

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Insulin regulates the activity of forkhead transcription factor Hnf-3beta/Foxa-2 by Akt-mediated phosphorylation and nuclear/cytosolic localization.

1 reference

https://api.crossref.org/works/10.1038%2FNATURE05861

7 January 2021

Identifiers

DOI

10.1038/NATURE05861

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17554339%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

31 December 2019

0 references

1 reference