Self-complementary AAVs induce more potent transgene product-specific immune responses compared to a single-stranded genome (Q24625426)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22186792%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

title

Self-complementary AAVs induce more potent transgene product-specific immune responses compared to a single-stranded genome (English)

1 reference

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19 January 2020

0 references

7

1 reference

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19 January 2020

author name string

TeLang Wu

1

1 reference

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19 January 2020

Katrin Töpfer

2

1 reference

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19 January 2020

Shih-Wen Lin

3

1 reference

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19 January 2020

Hua Li

4

1 reference

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19 January 2020

Ang Bian

5

1 reference

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19 January 2020

Xiang Y Zhou

6

1 reference

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19 January 2020

Hildegund C J Ertl

8

1 reference

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19 January 2020

language of work or name

English

0 references

publication date

20 December 2011

1 reference

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19 January 2020

1 reference

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19 January 2020

volume

20

1 reference

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19 January 2020

page(s)

572-579

1 reference

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19 January 2020

issue

3

1 reference

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Gene therapy for Leber's congenital amaurosis is safe and effective through 1.5 years after vector administration

19 January 2020

cites work

1 reference

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Adeno-associated virus: from defective virus to effective vector

7 April 2017

1 reference

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Differential activation of innate immune responses by adenovirus and adeno-associated virus vectors

7 April 2017

1 reference

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Age-dependent effects of RPE65 gene therapy for Leber's congenital amaurosis: a phase 1 dose-escalation trial

7 April 2017

1 reference

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Self-complementary recombinant adeno-associated virus (scAAV) vectors promote efficient transduction independently of DNA synthesis

7 April 2017

1 reference

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Successful transduction of liver in hemophilia by AAV-Factor IX and limitations imposed by the host immune response

7 April 2017

1 reference

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The genome of self-complementary adeno-associated viral vectors increases Toll-like receptor 9-dependent innate immune responses in the liver

7 April 2017

1 reference

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Adeno-associated virus vectors serotype 2 induce prolonged proliferation of capsid-specific CD8+ T cells in mice.

27 September 2017

1 reference

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Sustained alpha-sarcoglycan gene expression after gene transfer in limb-girdle muscular dystrophy, type 2D.

27 September 2017

1 reference

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A phase I study of aromatic L-amino acid decarboxylase gene therapy for Parkinson's disease

27 September 2017

1 reference

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Understanding inhibitor development in haemophilia A: towards clinical prediction and prevention strategies

27 September 2017

1 reference

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Sustained transgene expression despite T lymphocyte responses in a clinical trial of rAAV1-AAT gene therapy

27 September 2017

1 reference

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AAV-1-mediated gene transfer to skeletal muscle in humans results in dose-dependent activation of capsid-specific T cells

27 September 2017

1 reference

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Optimization of self-complementary AAV vectors for liver-directed expression results in sustained correction of hemophilia B at low vector dose

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293612

Recombinant adeno-associated virus vectors induce functionally impaired transgene product-specific CD8+ T cells in mice

27 September 2017

1 reference

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The state of the art of adeno-associated virus-based vectors in gene therapy

27 September 2017

1 reference

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Multiple immunizations with adenovirus and MVA vectors improve CD8+ T cell functionality and mucosal homing

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293612

Safe and efficient transduction of the liver after peripheral vein infusion of self-complementary AAV vector results in stable therapeutic expression of human FIX in nonhuman primates

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293612

Self-complementary adeno-associated virus vectors containing a novel liver-specific human factor IX expression cassette enable highly efficient transduction of murine and nonhuman primate liver

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3293612

New recombinant serotypes of AAV vectors.

27 September 2017

1 reference

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Efficacy of an adeno-associated virus 8-pseudotyped vector in glycogen storage disease type II.

27 September 2017

1 reference

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Viral persistence alters CD8 T-cell immunodominance and tissue distribution and results in distinct stages of functional impairment

27 September 2017

1 reference

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Characterization of tissue tropism determinants of adeno-associated virus type 1.

27 September 2017

1 reference

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An experimental vaccine expressing wild-type p53 induces protective immunity against glioblastoma cells with high levels of endogenous p53.

27 September 2017

1 reference

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Cross-packaging of a single adeno-associated virus (AAV) type 2 vector genome into multiple AAV serotypes enables transduction with broad specificity

27 September 2017

1 reference

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Adeno-associated virus vector carrying human minidystrophin genes effectively ameliorates muscular dystrophy in mdx mouse model

27 September 2017

1 reference

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Intramuscular administration of AAV1-lipoprotein lipase S447X lowers triglycerides in lipoprotein lipase-deficient patients

27 September 2017

1 reference

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Comparative analysis of adeno-associated viral vector serotypes 1, 2, 5, 7, and 8 in mouse brain

28 November 2018

1 reference

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A simple method for improved assay demonstrates that HIV p24 antigen is present as immune complexes in most sera from HIV-infected individuals

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22186792

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/MT.2011.280

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22186792%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:22186792%20AND%20SRC:MED&resulttype=core&format=json

19 January 2020

1 reference