The role of CCN2 in cartilage and bone development (Q24627602)

Journal of Cell Communication and Signaling

Europe PubMed Central

title

The role of CCN2 in cartilage and bone development (English)

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Satoshi Kubota

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Masaharu Takigawa

series ordinal

2

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language of work or name

English

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publication date

August 2011

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published in

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Functions and mechanisms of action of CCN matricellular proteins

volume

5

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issue

3

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page(s)

209-17

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cites work

1 reference

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CT domain of CCN2/CTGF directly interacts with fibronectin and enhances cell adhesion of chondrocytes through integrin alpha5beta1

7 April 2017

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Connective tissue growth factor coordinates chondrogenesis and angiogenesis during skeletal development

7 April 2017

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Proposal for a unified CCN nomenclature

7 April 2017

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N-terminal domains of CCN family 2/connective tissue growth factor bind to aggrecan

7 April 2017

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Novel transcription-factor-like function of human matrix metalloproteinase 3 regulating the CTGF/CCN2 gene

7 April 2017

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All in the CCN family: essential matricellular signaling modulators emerge from the bunker

7 April 2017

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Connective tissue growth factor CCN2 interacts with and activates the tyrosine kinase receptor TrkA

7 April 2017

1 reference

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Activated human platelets release connective tissue growth factor

7 April 2017

1 reference

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Connective tissue growth factor (CCN2) induces adhesion of rat activated hepatic stellate cells by binding of its C-terminal domain to integrin alpha(v)beta(3) and heparan sulfate proteoglycan

7 April 2017

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The low density lipoprotein receptor-related protein/alpha2-macroglobulin receptor is a receptor for connective tissue growth factor

7 April 2017

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Identification of an RNA element that confers post-transcriptional repression of connective tissue growth factor/hypertrophic chondrocyte specific 24 (ctgf/hcs24) gene: similarities to retroviral RNA-protein interactions

7 April 2017

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Activation-dependent adhesion of human platelets to Cyr61 and Fisp12/mouse connective tissue growth factor is mediated through integrin alpha(IIb)beta(3)

7 April 2017

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7 April 2017

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Cooperative regulation of chondrocyte differentiation by CCN2 and CCN3 shown by a comprehensive analysis of the CCN family proteins in cartilage

21 January 2018

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Expression and roles of connective tissue growth factor in Meckel's cartilage development

7 April 2017

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Ethanol-stimulated differentiated functions of human or mouse hepatic stellate cells are mediated by connective tissue growth factor

7 April 2017

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CCN family 2/connective tissue growth factor (CCN2/CTGF) promotes osteoclastogenesis via induction of and interaction with dendritic cell-specific transmembrane protein (DC-STAMP).

27 September 2017

1 reference

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Connective tissue growth factor is required for skeletal development and postnatal skeletal homeostasis in male mice

27 September 2017

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On the road to reading the RNA-interference code

27 September 2017

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Connective tissue growth factor (CTGF, CCN2) gene regulation: a potent clinical bio-marker of fibroproliferative disease?

27 September 2017

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Posttranscriptional regulation of chicken ccn2 gene expression by nucleophosmin/B23 during chondrocyte differentiation

27 September 2017

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Role of CCN2/CTGF/Hcs24 in bone growth

27 September 2017

1 reference

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Possible role of LRP1, a CCN2 receptor, in chondrocytes

27 September 2017

1 reference

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Roles of PKC, PI3K and JNK in multiple transduction of CCN2/CTGF signals in chondrocytes

27 September 2017

1 reference

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Hypoxic regulation of stability of connective tissue growth factor/CCN2 mRNA by 3'-untranslated region interacting with a cellular protein in human chondrosarcoma cells.

27 September 2017

1 reference

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CCN proteins: multifunctional signalling regulators

27 September 2017

1 reference

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Expression of connective tissue growth factor/hypertrophic chondrocyte-specific gene product 24 (CTGF/Hcs24) during fracture healing

27 September 2017

1 reference

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A novel cis-element that enhances connective tissue growth factor gene expression in chondrocytic cells

27 September 2017

1 reference

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Connective-tissue growth factor (CTGF) modulates cell signalling by BMP and TGF-beta

27 September 2017

1 reference

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Connective tissue growth factor binds vascular endothelial growth factor (VEGF) and inhibits VEGF-induced angiogenesis

27 September 2017

1 reference

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Regulation of mandibular growth and morphogenesis

27 September 2017

1 reference

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Effects of CTGF/Hcs24, a hypertrophic chondrocyte-specific gene product, on the proliferation and differentiation of osteoblastic cells in vitro

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145877

Effects of CTGF/Hcs24, a product of a hypertrophic chondrocyte-specific gene, on the proliferation and differentiation of chondrocytes in culture

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145877

Cloning of a mRNA preferentially expressed in chondrocytes by differential display-PCR from a human chondrocytic cell line that is identical with connective tissue growth factor (CTGF) mRNA.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145877

The triple origin of skull in higher vertebrates: a study in quail-chick chimeras

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145877

Connective tissue growth factor: a cysteine-rich mitogen secreted by human vascular endothelial cells is related to the SRC-induced immediate early gene product CEF-10

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145877

CCN family 2/connective tissue growth factor modulates BMP signalling as a signal conductor, which action regulates the proliferation and differentiation of chondrocytes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145877

Connective tissue growth factor enhances osteoblastogenesis in vitro

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145877

Functional requirement of CCN2 for intramembranous bone formation in embryonic mice

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145877

Nucleus pulposus notochord cells secrete connective tissue growth factor and up-regulate proteoglycan expression by intervertebral disc chondrocytes.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145877

Establishment of a clonal human chondrosarcoma cell line with cartilage phenotypes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3145877

Promotion of bone regeneration by CCN2 incorporated into gelatin hydrogel.

30 May 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12079-011-0123-5

3' UTRs are the primary regulators of gene expression in the C. elegans germline

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12079-011-0123-5

Regeneration of defects in articular cartilage in rat knee joints by CCN2 (connective tissue growth factor).

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12079-011-0123-5

Regulation of chondrocytic phenotype by micro RNA 18a: involvement of Ccn2/Ctgf as a major target gene.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12079-011-0123-5

Promotion of hydroxyapatite-associated, stem cell-based bone regeneration by CCN2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12079-011-0123-5

Expression of connective tissue growth factor in bone: its role in osteoblast proliferation and differentiation in vitro and bone formation in vivo.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12079-011-0123-5

Retinoid signaling regulates CTGF expression in hypertrophic chondrocytes with differential involvement of MAP kinases

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12079-011-0123-5

Thrombopoietic-mesenchymal interaction that may facilitate both endochondral ossification and platelet maturation via CCN2.

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS12079-011-0123-5

Connective tissue growth factor induces the proliferation, migration, and tube formation of vascular endothelial cells in vitro, and angiogenesis in vivo

21 January 2018

1 reference

12 December 2020

Expression and localization of connective tissue growth factor (CTGF/Hcs24/CCN2) in osteoarthritic cartilage

1 reference

12 December 2020

Expression of neurotrophins and their receptors (TRK) during fracture healing

1 reference

12 December 2020

CCN family 2/connective tissue growth factor (CCN2/CTGF) stimulates proliferation and differentiation of auricular chondrocytes

1 reference

12 December 2020

CTGF/Hcs24, a hypertrophic chondrocyte-specific gene product, stimulates proliferation and differentiation, but not hypertrophy of cultured articular chondrocytes

1 reference

12 December 2020

CTGF/Hcs24, hypertrophic chondrocyte-specific gene product, interacts with perlecan in regulating the proliferation and differentiation of chondrocytes

1 reference

12 December 2020

Abundant retention and release of connective tissue growth factor (CTGF/CCN2) by platelets

1 reference

12 December 2020