Macrocyclic histone deacetylase inhibitors (Q24629065)

Europe PubMed Central

title

Macrocyclic histone deacetylase inhibitors (English)

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author name string

Sandra C Mwakwari

1

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Vishal Patil

2

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William Guerrant

3

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Adegboyega K Oyelere

Current Topics in Medicinal Chemistry

4

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language of work or name

English

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publication date

2010

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published in

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volume

10

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issue

14

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page(s)

1423-40

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cites work

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Potent antimalarial activity of histone deacetylase inhibitor analogues.

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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A phase 1 and pharmacodynamic study of depsipeptide (FK228) in chronic lymphocytic leukemia and acute myeloid leukemia.

27 September 2017

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Histone deacetylase inhibitors open new doors in cancer therapy

27 September 2017

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27 September 2017

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Antimalarial and antileishmanial activities of aroyl-pyrrolyl-hydroxyamides, a new class of histone deacetylase inhibitors

27 September 2017

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A phase I trial of depsipeptide (FR901228) in patients with advanced cancer.

27 September 2017

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Phase I trial of the histone deacetylase inhibitor, depsipeptide (FR901228, NSC 630176), in patients with refractory neoplasms

27 September 2017

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Broad spectrum antiprotozoal agents that inhibit histone deacetylase: structure-activity relationships of apicidin. Part 1.

27 September 2017

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27 September 2017

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Apicidin, a histone deacetylase inhibitor, inhibits proliferation of tumor cells via induction of p21WAF1/Cip1 and gelsolin

27 September 2017

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27 September 2017

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FR901228, a novel antitumor bicyclic depsipeptide produced by Chromobacterium violaceum No. 968. II. Structure determination

27 September 2017

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Multiple functions of dynamic histone acetylation

27 September 2017

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27 September 2017

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n-Butyrate causes histone modification in HeLa and Friend erythroleukaemia cells

27 September 2017

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Novel inhibitor of Plasmodium histone deacetylase that cures P. berghei-infected mice

27 September 2017

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Antimalarial activity of phenylthiazolyl-bearing hydroxamate-based histone deacetylase inhibitors

30 May 2018

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Trapoxin, an antitumor cyclic tetrapeptide, is an irreversible inhibitor of mammalian histone deacetylase

30 May 2018

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Isolation and structural elucidation of new cyclotetrapeptides, trapoxins A and B, having detransformation activities as antitumor agents

30 May 2018

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Phase II, two-stage, single-arm trial of the histone deacetylase inhibitor (HDACi) romidepsin in metastatic castration-resistant prostate cancer (CRPC).

30 May 2018

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HDAC inhibitors: magic bullets, dirty drugs or just another targeted therapy

28 November 2018

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Total Synthesis of Azumamide E and Sugar Amino Acid-Containing Analogue

28 November 2018

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Total synthesis and molecular target of largazole, a histone deacetylase inhibitor

28 November 2018

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Synthesis and structure-activity relationship of histone deacetylase (HDAC) inhibitors with triazole-linked cap group

28 November 2018

1 reference

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Molecular design of histone deacetylase inhibitors by aromatic ring shifting in chlamydocin framework.

28 November 2018

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Design and synthesis of a potent histone deacetylase inhibitor

28 November 2018

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Additive neuroprotective effects of a histone deacetylase inhibitor and a catalytic antioxidant in a transgenic mouse model of amyotrophic lateral sclerosis

28 November 2018

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Crystal structure of a bacterial class 2 histone deacetylase homologue

28 November 2018

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Increased expression of histone deacetylase 2 is found in human gastric cancer.

28 November 2018

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Stage-specific antileishmanial activity of an inhibitor of SIR2 histone deacetylase.

28 November 2018

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Identification of a potent non-hydroxamate histone deacetylase inhibitor by mechanism-based drug design

28 November 2018

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Structural snapshots of human HDAC8 provide insights into the class I histone deacetylases

28 November 2018

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Upregulation and nuclear recruitment of HDAC1 in hormone refractory prostate cancer.

28 November 2018

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Nonpeptide luteinizing hormone-releasing hormone antagonists derived from erythromycin A: design, synthesis, and biological activity of cladinose replacement analogues

28 November 2018

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Histone Deacetylase Inhibitors

28 November 2018

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Difficult Macrocyclizations: New Strategies for Synthesizing Highly Strained Cyclic Tetrapeptides

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144151

Predicting the conformational states of cyclic tetrapeptides.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144151

Succinimide hydroxamic acids as potent inhibitors of histone deacetylase (HDAC).

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144151

FK228 (depsipeptide) as a natural prodrug that inhibits class I histone deacetylases

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144151

Structure and chemistry of apicidins, a class of novel cyclic tetrapeptides without a terminal alpha-keto epoxide as inhibitors of histone deacetylase with potent antiprotozoal activities.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144151

Expression profile of histone deacetylase 1 in gastric cancer tissues.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144151

Apicidin, a histone deacetylase inhibitor, induces apoptosis and Fas/Fas ligand expression in human acute promyelocytic leukemia cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144151

Inhibitor of histone deacetylation, depsipeptide (FR901228), in the treatment of peripheral and cutaneous T-cell lymphoma: a case report

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144151

Cyclic hydroxamic-acid-containing peptide 31, a potent synthetic histone deacetylase inhibitor with antitumor activity.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3144151

Phosphinic pseudo-tripeptides as potent inhibitors of matrix metalloproteinases: a structure-activity study

28 November 2018

1 reference

12 December 2020

Hybrid polar histone deacetylase inhibitor induces apoptosis and CD95/CD95 ligand expression in human neuroblastoma

1 reference

12 December 2020

Substrate and inhibitor specificity of class 1 and class 2 histone deacetylases

1 reference

12 December 2020

Cardiotoxicity of histone deacetylase inhibitor depsipeptide in patients with metastatic neuroendocrine tumors

1 reference

12 December 2020

Molecular insights into azumamide e histone deacetylases inhibitory activity

1 reference

12 December 2020

Total synthesis of azumamide A and azumamide E, evaluation as histone deacetylase inhibitors, and design of a more potent analogue

1 reference

12 December 2020

Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo

1 reference

12 December 2020

Total synthesis of spiruchostatin B, a potent histone deacetylase inhibitor, from a microorganism

1 reference

12 December 2020

Total synthesis of spiruchostatin A, a potent histone deacetylase inhibitor

1 reference

12 December 2020

[Isolation and structural clarification of chlamydocin]

1 reference

12 December 2020

Suppression of histone deacetylation in vivo and in vitro by sodium butyrate

1 reference

12 December 2020

Studies on WF-3161, a new antitumor antibiotic

1 reference

12 December 2020

Structure and solution conformation of the cytostatic cyclic tetrapeptide WF-3161, cyclo[L-leucyl-L-pipecolyl-L-(2-amino-8-oxo-9, 10-epoxydecanoyl)-D-phenylalanyl]

1 reference

12 December 2020

Isolation and structural elucidation of new cyclotetrapeptides, trapoxins A and B, having detransformation activities as antitumor agents.

1 reference

12 April 2024

https://opencitations.net/index/api/v1/citations/10.7164/ANTIBIOTICS.43.1524

Identifiers

DOI

10.2174/156802610792232079

1 reference

2119003

2119003

1 reference

1 reference

1 reference