Insulin receptor signaling in osteoblasts regulates postnatal bone acquisition and body composition (Q24629773)

Twist basic helix-loop-helix transcription factor 2

GOA release 2020-03-11

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GOA release 2020-03-11

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10

Jens C Brüning

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author name string

Keertik Fulzele

1

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Ryan C Riddle

2

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Douglas J DiGirolamo

3

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Xuemei Cao

4

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Chao Wan

5

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Dongquan Chen

6

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Marie-Claude Faugere

7

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Susan Aja

8

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Mehboob A Hussain

9

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Thomas L Clemens

Association between serum osteocalcin and markers of metabolic phenotype

11

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language of work or name

English

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publication date

23 July 2010

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published in

Cell

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volume

142

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issue

2

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page(s)

309-19

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cites work

1 reference

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7 April 2017

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The uncarboxylated form of osteocalcin is associated with improved glucose tolerance and enhanced beta-cell function in middle-aged male subjects

7 April 2017

1 reference

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FoxOs are lineage-restricted redundant tumor suppressors and regulate endothelial cell homeostasis

7 April 2017

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A twist code determines the onset of osteoblast differentiation

7 April 2017

1 reference

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The forkhead transcription factor Foxo1 links insulin signaling to Pdx1 regulation of pancreatic beta cell growth

7 April 2017

1 reference

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The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity

7 April 2017

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Leptin inhibits bone formation through a hypothalamic relay: a central control of bone mass

7 April 2017

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Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature Committee

7 April 2017

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FoxO1 expression in osteoblasts regulates glucose homeostasis through regulation of osteocalcin in mice

7 April 2017

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Bone as an endocrine organ.

27 September 2017

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The sympathetic tone mediates leptin's inhibition of insulin secretion by modulating osteocalcin bioactivity

27 September 2017

1 reference

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Reciprocal regulation of bone and energy metabolism

27 September 2017

1 reference

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Osteocalcin differentially regulates beta cell and adipocyte gene expression and affects the development of metabolic diseases in wild-type mice

27 September 2017

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Convergence between bone and energy homeostases: leptin regulation of bone mass

27 September 2017

1 reference

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Increased pancreatic beta-cell proliferation mediated by CREB binding protein gene activation

27 September 2017

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Transgenic rescue of insulin receptor-deficient mice

27 September 2017

1 reference

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FoxOs at the crossroads of cellular metabolism, differentiation, and transformation

27 September 2017

1 reference

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The forkhead transcription factor Foxo1 regulates adipocyte differentiation

27 September 2017

1 reference

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Leptin regulates bone formation via the sympathetic nervous system

27 September 2017

1 reference

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Regulation of insulin action and pancreatic beta-cell function by mutated alleles of the gene encoding forkhead transcription factor Foxo1.

27 September 2017

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Insulin-like growth factor-I in diabetes mellitus: its physiology, metabolic effects, and potential clinical utility

27 September 2017

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Low bone density with normal bone turnover in ovariectomized and streptozotocin-induced diabetic rats

27 September 2017

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The influence of diabetes mellitus on the healing of closed fractures.

27 September 2017

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The characterization, regulation, and function of insulin receptors on osteoblast-like clonal osteosarcoma cell line

27 September 2017

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The effects of systemic insulin, insulin-like growth factor-I and growth hormone on bone growth and turnover in spontaneously diabetic BB rats

30 May 2018

1 reference

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Disruption of the insulin-like growth factor type 1 receptor in osteoblasts enhances insulin signaling and action.

30 May 2018

1 reference

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Normal bone density obtained in the absence of insulin receptor expression in bone.

28 November 2018

1 reference

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The effects of local insulin delivery on diabetic fracture healing

28 November 2018

1 reference

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The effect of streptozotocin-induced chronic diabetes mellitus on bone and mineral homeostasis in the rat

28 November 2018

1 reference

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Multiple Hormonal Mechanisms for the Control of Collagen Synthesis in an Osteoblast-Like Cell Line, MMB-1*

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2925155

Type 1 and type 2 diabetes and incident hip fractures in postmenopausal women

28 November 2018

1 reference

12 December 2020

Osteoblast-specific knockout of the insulin-like growth factor (IGF) receptor gene reveals an essential role of IGF signaling in bone matrix mineralization

1 reference

12 December 2020

Effect of renal function on plasma levels of bone Gla-protein

1 reference

12 December 2020

Diminished bone formation in experimental diabetes. Relationship to osteoid maturation and mineralization

1 reference

12 December 2020

Characterization of the effect of insulin on collagen synthesis in fetal rat bone

1 reference

12 December 2020

Glucose transport system in UMR-106-01 osteoblastic osteosarcoma cells: regulation by insulin

1 reference

12 December 2020

Prospective study of diabetes and risk of hip fracture: the Nurses' Health Study

1 reference

12 December 2020

Osteopenia in insulin-dependent diabetes mellitus; prevalence and aspects of pathophysiology

1 reference

12 December 2020

Bone and mineral metabolism in BB rats with long-term diabetes. Decreased bone turnover and osteoporosis

1 reference

12 December 2020

Different pattern of alkaline phosphatase, osteopontin, and osteocalcin expression in developing rat bone visualized by in situ hybridization

1 reference

12 December 2020

A muscle-specific insulin receptor knockout exhibits features of the metabolic syndrome of NIDDM without altering glucose tolerance

1 reference

12 December 2020

10.1016/J.CELL.2010.06.002

Identifiers

DOI

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1783040

1783040

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1 reference

1 reference