Plumbagin inhibits proliferative and inflammatory responses of T cells independent of ROS generation but by modulating intracellular thiols (Q24631319)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20564204%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

title

Plumbagin inhibits proliferative and inflammatory responses of T cells independent of ROS generation but by modulating intracellular thiols (English)

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6 February 2020

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1

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6 February 2020

author name string

Deepak Sharma

2

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6 February 2020

Santosh K Sandur

3

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6 February 2020

G Subrahmanyam

4

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6 February 2020

Sunil Krishnan

5

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6 February 2020

T B Poduval

6

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6 February 2020

K B Sainis

7

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6 February 2020

language of work or name

English

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publication date

1 August 2010

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Journal of Cellular Biochemistry

6 February 2020

published in

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6 February 2020

volume

110

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6 February 2020

issue

5

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6 February 2020

page(s)

1082-1093

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Plumbagin, a novel Nrf2/ARE activator, protects against cerebral ischemia

6 February 2020

cites work

1 reference

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Dynamic redox control of NF-kappaB through glutaredoxin-regulated S-glutathionylation of inhibitory kappaB kinase beta

7 April 2017

1 reference

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Cytotoxic action of juglone and plumbagin: a mechanistic study using HaCaT keratinocytes

7 April 2017

1 reference

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Thiol chemistry and specificity in redox signaling

7 April 2017

1 reference

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Distinct Cysteine Residues in Keap1 Are Required for Keap1-Dependent Ubiquitination of Nrf2 and for Stabilization of Nrf2 by Chemopreventive Agents and Oxidative Stress

7 April 2017

1 reference

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Molecular events in the activation of B cells and macrophages by a non-microbial TLR4 agonist, G1-4A from Tinospora cordifolia

7 April 2017

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Bcr-Abl-mediated redox regulation of the PI3K/AKT pathway

27 September 2017

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Redox regulation of nuclear post-translational modifications during NF-kappaB activation

27 September 2017

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Molecular mechanisms mediating oxidative stress-induced T-cell suppression in cancer

27 September 2017

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Protein S-glutathionylation: a regulatory device from bacteria to humans.

27 September 2017

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Modification of the cysteine residues in IkappaBalpha kinase and NF-kappaB (p65) by xanthohumol leads to suppression of NF-kappaB-regulated gene products and potentiation of apoptosis in leukemia cells

27 September 2017

1 reference

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Glutathionylation regulates IkappaB.

27 September 2017

1 reference

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Thiol oxidation in signaling and response to stress: detection and quantification of physiological and pathophysiological thiol modifications.

27 September 2017

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Induction of apoptosis by plumbagin through reactive oxygen species-mediated inhibition of topoisomerase II.

27 September 2017

1 reference

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Thimerosal induces TH2 responses via influencing cytokine secretion by human dendritic cells

27 September 2017

1 reference

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Plumbagin (5-hydroxy-2-methyl-1,4-naphthoquinone) suppresses NF-kappaB activation and NF-kappaB-regulated gene products through modulation of p65 and IkappaBalpha kinase activation, leading to potentiation of apoptosis induced by cytokine and chemot

27 September 2017

1 reference

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Molecular mechanism of nrf2 activation by oxidative stress

27 September 2017

1 reference

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Plumbagin induces reactive oxygen species, which mediate apoptosis in human cervical cancer cells

27 September 2017

1 reference

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Control of Bcl-2 expression by reactive oxygen species

27 September 2017

1 reference

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Betulinic acid suppresses carcinogen-induced NF-kappa B activation through inhibition of I kappa B alpha kinase and p65 phosphorylation: abrogation of cyclooxygenase-2 and matrix metalloprotease-9.

27 September 2017

1 reference

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T cell apoptosis and reactive oxygen species

27 September 2017

1 reference

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Identification by redox proteomics of glutathionylated proteins in oxidatively stressed human T lymphocytes

27 September 2017

1 reference

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Effect of in vitro generation of oxygen free radicals on T cell function in young and old rats

27 September 2017

1 reference

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Chemical depletion of glutathione in vivo

27 September 2017

1 reference

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Spatial distribution, kinetics, signaling and cytokine production during homeostasis driven proliferation of CD4+ T cells

27 September 2017

1 reference

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Thioredoxin reductase as a potential molecular target for anticancer agents that induce oxidative stress

30 May 2018

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Oxidative stress suppresses transcription factor activities in stimulated lymphocytes.

30 May 2018

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Anti-inflammatory effects of plumbagin are mediated by inhibition of NF-kappaB activation in lymphocytes

30 May 2018

1 reference

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Immunomodulatory and radioprotective effects of lignans derived from fresh nutmeg mace (Myristica fragrans) in mammalian splenocytes.

28 November 2018

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Differential modulation of mitogen driven proliferation and homeostasis driven proliferation of T cells by rapamycin, Ly294002 and chlorophyllin.

28 November 2018

1 reference

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Antiapoptotic and immunomodulatory effects of chlorophyllin.

28 November 2018

1 reference

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Redox modifications of protein-thiols: emerging roles in cell signaling

28 November 2018

1 reference

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Antioxidant properties of Plumbago zeylanica, an Indian medicinal plant and its active ingredient, plumbagin

28 November 2018

1 reference

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Synthesis of plumbagin derivatives and their inhibitory activities against Ehrlich ascites carcinoma in vivo and Leishmania donovani Promastigotes in vitro

28 November 2018

1 reference

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Inhibition of activated/memory (CD45RO(+)) T cells by oxidative stress associated with block of NF-kappaB activation

28 November 2018

1 reference

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Longitudinal exposure of human T lymphocytes to weak oxidative stress suppresses transmembrane and nuclear signal transduction

28 November 2018

1 reference

12 December 2020

Evaluation of methods for measuring cellular glutathione content using flow cytometry

1 reference

12 December 2020

Niosomal plumbagin with reduced toxicity and improved anticancer activity in BALB/C mice

1 reference

12 December 2020

Antioxidant Defense System in Differentially Hydrogen Peroxide Sensitive L5178Y Sublines

1 reference

12 December 2020

Thiol-mediated inhibition of FAS and CD2 apoptotic signaling in activated human peripheral T cells

1 reference

12 December 2020

Reduced toxicity and enhanced antitumor efficacy of betacyclodextrin plumbagin inclusion complex in mice bearing Ehrlich ascites carcinoma

1 reference

12 December 2020

Pre-exposure to oxidative stress decreases the nuclear factor-kappa B-dependent transcription in T lymphocytes

1 reference

12 December 2020

Identification of oxidant-sensitive proteins: TNF-alpha induces protein glutathiolation

1 reference

12 December 2020

Plumbagin: A study of its anticancer, antibacterial & antifungal properties

1 reference

12 December 2020

Differential mechanisms of cell killing by redox cycling and arylating quinones

1 reference

12 December 2020

Identifiers

DOI

10.1002/JCB.22620

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20564204%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20564204%20AND%20SRC:MED&resulttype=core&format=json

6 February 2020

2 references