Mast cell homeostasis and the JAK-STAT pathway (Q24632515)

Europe PubMed Central

title

Mast cell homeostasis and the JAK-STAT pathway (English)

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J K Morales

1

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Y T Falanga

2

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A Depcrynski

3

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J Fernando

4

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J J Ryan

New developments in mast cell biology

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language of work or name

English

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publication date

December 2010

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published in

Genes and Immunity

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volume

11

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issue

8

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page(s)

599-608

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cites work

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7 April 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Stat1 combines signals derived from IFN-gamma and LPS receptors during macrophage activation

27 September 2017

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27 September 2017

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Stat1 serine phosphorylation occurs independently of tyrosine phosphorylation and requires an activated Jak2 kinase

27 September 2017

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Characterization of a mast cell line that lacks the extracellular domain of membrane c-kit

27 September 2017

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27 September 2017

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27 September 2017

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Enhancement of antiproliferative activity of gamma interferon by the specific inhibition of tyrosine dephosphorylation of Stat1.

27 September 2017

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27 September 2017

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Tyrosyl phosphorylation and DNA binding activity of signal transducers and activators of transcription (STAT) proteins in hematopoietic cell lines transformed by Bcr/Abl

27 September 2017

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Stat1 depends on transcriptional synergy with Sp1.

27 September 2017

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The antiviral state induced by alpha interferon and gamma interferon requires transcriptionally active Stat1 protein.

27 September 2017

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Transcription factor p91 interacts with the epidermal growth factor receptor and mediates activation of the c-fos gene promoter

27 September 2017

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27 September 2017

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Complementation of a mutant cell line: central role of the 91 kDa polypeptide of ISGF3 in the interferon-alpha and -gamma signal transduction pathways

27 September 2017

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Identification of mutations in the coding sequence of the proto-oncogene c-kit in a human mast cell leukemia cell line causing ligand-independent activation of c-kit product

27 September 2017

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Cooperative transcriptional activity of Jun and Stat3 beta, a short form of Stat3

27 September 2017

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Identification of a point mutation in the catalytic domain of the protooncogene c-kit in peripheral blood mononuclear cells of patients who have mastocytosis with an associated hematologic disorder

27 September 2017

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Impaired IL-12 responses and enhanced development of Th2 cells in Stat4-deficient mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099592

Oncogenic Kit controls neoplastic mast cell growth through a Stat5/PI3-kinase signaling cascade

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099592

PKC412 inhibits in vitro growth of neoplastic human mast cells expressing the D816V-mutated variant of KIT: comparison with AMN107, imatinib, and cladribine (2CdA) and evaluation of cooperative drug effects

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099592

Blockade of the Bcr-Abl kinase activity induces apoptosis of chronic myelogenous leukemia cells by suppressing signal transducer and activator of transcription 5-dependent expression of Bcl-xL

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099592

Interleukin-6-induced STAT3 transactivation and Ser727 phosphorylation involves Vav, Rac-1 and the kinase SEK-1/MKK-4 as signal transduction components

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099592

Regulation of T helper cell differentiation by STAT molecules.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099592

STAT6 is required for IL-4-induced germline Ig gene transcription and switch recombination.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099592

Prediction of the structure of human Janus kinase 2 (JAK2) comprising JAK homology domains 1 through 7.

30 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2010.35

Kit and FcepsilonRI mediate unique and convergent signals for release of inflammatory mediators from human mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2010.35

Lyn contributes to regulation of multiple Kit-dependent signaling pathways in murine bone marrow mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2010.35

SLIM is a nuclear ubiquitin E3 ligase that negatively regulates STAT signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2010.35

IL-5 and granulocyte-macrophage colony-stimulating factor activate STAT3 and STAT5 and promote Pim-1 and cyclin D3 protein expression in human eosinophils

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2010.35

IFNs and STATs in innate immunity to microorganisms

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2010.35

Stat5 expression is required for IgE-mediated mast cell function

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2010.35

Phospho-STAT5 and phospho-Akt expression in chronic myeloproliferative neoplasms.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2010.35

Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human malignancies

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2010.35

Identification of proapoptotic Bim as a tumor suppressor in neoplastic mast cells: role of KIT D816V and effects of various targeted drugs

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2010.35

JAK2 inhibitors: not the next imatinib but researchers see other possibilities.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2010.35

IL-10 inhibits Fc epsilon RI expression in mouse mast cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2010.35

Interleukin-10 induces apoptosis in developing mast cells and macrophages

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2010.35

IL-10 suppresses mast cell IgE receptor expression and signaling in vitro and in vivo

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2010.35

TGF-beta1 inhibits late-stage mast cell maturation

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2010.35

Interleukin-4 and -13 expression is co-localized to mast cells within the airway smooth muscle in asthma

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2010.35

Mast-cell infiltration of airway smooth muscle in asthma.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FGENE.2010.35

Inhibition of Kit expression by IL-4 and IL-10 in murine mast cells: role of STAT6 and phosphatidylinositol 3'-kinase

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099592

Interferon-induced nuclear factors that bind a shared promoter element correlate with positive and negative transcriptional control

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3099592

Interleukin-4-triggered, STAT6-dependent production of a factor that induces mouse mast cell apoptosis

28 November 2018

1 reference

12 December 2020

STAT5 activation induced by diabetic LDL depends on LDL glycation and occurs via src kinase activity

1 reference

12 December 2020

SOCS-1 participates in negative regulation of LPS responses

1 reference

12 December 2020

JAK2, a third member of the JAK family of protein tyrosine kinases

1 reference

12 December 2020

Interferon-dependent tyrosine phosphorylation of a latent cytoplasmic transcription factor

1 reference

12 December 2020

IL-13 induces proliferation, Ig isotype switching, and Ig synthesis by immature human fetal B cells

1 reference

12 December 2020

Steel factor induces serine phosphorylation of Stat3 in human growth factor-dependent myeloid cell lines

1 reference

12 December 2020

Human mast cell apoptosis is regulated through Bcl-2 and Bcl-XL

1 reference

12 December 2020

[Role of eotaxin in the pathophysiology of asthma]

1 reference

12 December 2020

Role for interleukin-3 in mast-cell and basophil development and in immunity to parasites

1 reference

12 December 2020

STAT6 deficiency in a mouse model of allergen-induced airways inflammation abolishes eosinophilia but induces infiltration of CD8+ T cells.

1 reference

12 December 2020

IL-4 preferentially activates a novel STAT6 isoform in mast cells

1 reference

12 December 2020