Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes (Q24633002)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20562852%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

title

Disruption of the clock components CLOCK and BMAL1 leads to hypoinsulinaemia and diabetes (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20562852%20AND%20SRC:MED&resulttype=core&format=json

Circadian locomotor output cycles kaput

5 February 2020

main subject

1 reference

Aryl hydrocarbon receptor nuclear translocator-like

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Joseph Takahashi

17

1 reference

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5 February 2020

author name string

Biliana Marcheva

1

1 reference

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5 February 2020

Kathryn Moynihan Ramsey

2

1 reference

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5 February 2020

Ethan D Buhr

3

1 reference

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5 February 2020

Yumiko Kobayashi

4

1 reference

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5 February 2020

Hong Su

5

1 reference

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5 February 2020

Caroline H Ko

6

1 reference

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5 February 2020

Ganka Ivanova

7

1 reference

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5 February 2020

Chiaki Omura

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20562852%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

Shelley Mo

9

1 reference

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5 February 2020

Martha H Vitaterna

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20562852%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

James P Lopez

11

1 reference

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5 February 2020

Louis H Philipson

12

1 reference

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5 February 2020

Christopher A Bradfield

13

1 reference

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5 February 2020

Seth D Crosby

14

1 reference

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5 February 2020

Lellean JeBailey

15

1 reference

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5 February 2020

Xiaozhong Wang

16

1 reference

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5 February 2020

Joseph Bass

18

1 reference

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5 February 2020

language of work or name

English

0 references

publication date

1 July 2010

1 reference

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5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20562852%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

volume

466

1 reference

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5 February 2020

page(s)

627-631

1 reference

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5 February 2020

issue

7306

1 reference

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Obesity and metabolic syndrome in circadian Clock mutant mice

5 February 2020

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

BMAL1 and CLOCK, two essential components of the circadian clock, are involved in glucose homeostasis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

PERIOD2::LUCIFERASE real-time reporting of circadian dynamics reveals persistent circadian oscillations in mouse peripheral tissues

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

Disruption of IRS-2 causes type 2 diabetes in mice

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

Coordinated transcription of key pathways in the mouse by the circadian clock

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

Positional cloning of the mouse circadian clock gene

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

Regulation of bile acid synthesis by the nuclear receptor Rev-erbalpha

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

Mop3 is an essential component of the master circadian pacemaker in mammals

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

Physiological significance of a peripheral tissue circadian clock

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

7 April 2017

The meter of metabolism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

Mammalian circadian biology: elucidating genome-wide levels of temporal organization

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

Direct evidence for the pancreatic lineage: NGN3+ cells are islet progenitors and are distinct from duct progenitors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

Extensive and divergent circadian gene expression in liver and heart

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

Resetting central and peripheral circadian oscillators in transgenic rats

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

A serum shock induces circadian gene expression in mammalian tissue culture cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

Nuclear receptor expression links the circadian clock to metabolism

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

Foxa2 controls vesicle docking and insulin secretion in mature Beta cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

Wnt signaling regulates pancreatic beta cell proliferation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

System-driven and oscillator-dependent circadian transcription in mice with a conditionally active liver clock

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

The biology of incretin hormones

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

Metabolism and the control of circadian rhythms

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

Loss of HNF-1alpha function in mice leads to abnormal expression of genes involved in pancreatic islet development and metabolism

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

Genetic components of the circadian clock regulate thrombogenesis in vivo.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

Clock mutation facilitates accumulation of cholesterol in the liver of mice fed a cholesterol and/or cholic acid diet

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

The molecular clock mediates leptin-regulated bone formation.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

Control mechanism of the circadian clock for timing of cell division in vivo.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

Insulinotropic glucagon-like peptide 1 agonists stimulate expression of homeodomain protein IDX-1 and increase islet size in mouse pancreas

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2920067

Abnormal patterns of insulin secretion in non-insulin-dependent diabetes mellitus

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20562852

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Multiple mechanisms regulate circadian expression of the gene for cholesterol 7alpha-hydroxylase (Cyp7a), a key enzyme in hepatic bile acid biosynthesis

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20562852

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identification of the circadian transcriptome in adult mouse skeletal muscle

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20562852

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NATURE09253

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20562852%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

5 February 2020

1011274307

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20562852%20AND%20SRC:MED&resulttype=core&format=json

5 February 2020

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20562852%20AND%20SRC:MED&resulttype=core&format=json