Disruption of IRS-2 causes type 2 diabetes in mice (Q24316112)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495343%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

title

Disruption of IRS-2 causes type 2 diabetes in mice (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495343%20AND%20SRC:MED&resulttype=core&format=json

Insulin receptor substrate 2

9 November 2019

main subject

type 2 diabetes

0 references

1 reference

glucose metabolic process

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Sebastian Pons

9

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495343%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Gerald I. Shulman

10

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495343%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

6

S Previs

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495343%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

author name string

D J Withers

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495343%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

J S Gutierrez

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495343%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

H Towery

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495343%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

D J Burks

4

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495343%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

J M Ren

5

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495343%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

Y Zhang

7

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495343%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

D Bernal

8

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495343%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

S Bonner-Weir

11

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495343%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

M F White

12

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495343%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

language of work or name

English

0 references

publication date

1 February 1998

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495343%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495343%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

volume

391

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495343%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

page(s)

900-904

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495343%20AND%20SRC:MED&resulttype=core&format=json

9 November 2019

issue

6670

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495343%20AND%20SRC:MED&resulttype=core&format=json

Insulin signal transduction and the IRS proteins

9 November 2019

cites work

1 reference

7 January 2021

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene.

1 reference

7 January 2021

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1.

1 reference

7 January 2021

Pathogenesis of NIDDM. A balanced overview

1 reference

7 January 2021

Role of IRS-2 in insulin and cytokine signalling

1 reference

7 January 2021

4PS/insulin receptor substrate (IRS)-2 is the alternative substrate of the insulin receptor in IRS-1-deficient mice

1 reference

7 January 2021

Overexpression of Glut4 protein in muscle increases basal and insulin-stimulated whole body glucose disposal in conscious mice.

1 reference

7 January 2021

Phosphatidylinositol 3-kinase activation is required for insulin stimulation of pp70 S6 kinase, DNA synthesis, and glucose transporter translocation

1 reference

7 January 2021

Insulin stimulation of glycogen synthesis and glycogen synthase activity is blocked by wortmannin and rapamycin in 3T3-L1 adipocytes: evidence for the involvement of phosphoinositide 3-kinase and p70 ribosomal protein-S6 kinase

1 reference

7 January 2021

Insulin regulation of phosphoenolpyruvate carboxykinase gene expression does not require activation of the Ras/mitogen-activated protein kinase signaling pathway

1 reference

7 January 2021

Apoptosis participates in the remodeling of the endocrine pancreas in the neonatal rat.

1 reference

7 January 2021

Differential signaling by insulin receptor substrate 1 (IRS-1) and IRS-2 in IRS-1-deficient cells

1 reference

7 January 2021

The IRS-2 gene on murine chromosome 8 encodes a unique signaling adapter for insulin and cytokine action.

1 reference

7 January 2021

Development of a novel polygenic model of NIDDM in mice heterozygous for IR and IRS-1 null alleles

1 reference

7 January 2021

The structure and function of p55PIK reveal a new regulatory subunit for phosphatidylinositol 3-kinase

1 reference

7 January 2021

Transplanted beta cell response to increased metabolic demand. Changes in beta cell replication and mass

1 reference

7 January 2021

Identifiers

DOI

10.1038/36116

2 references

Consolidated OpenCitations Corpus – April 2017

254541

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495343%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

9 November 2019

1019591506

0 references

254541

1 reference

Consolidated OpenCitations Corpus – April 2017

Consolidated OpenCitations Corpus – April 2017

2 references

254541

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:9495343%20AND%20SRC:MED&resulttype=core&format=json