Role of PD-1 in HIV pathogenesis and as target for therapy (Q24634293)

https://scigraph.springernature.com/pub.10.1007/s11904-011-0106-4

PubMed

volume

9

0 references

issue

1

0 references

page(s)

81-90

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exact match

0 references

cites work

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Upregulation of PD-1 Expression on Circulating and Intrahepatic Hepatitis C Virus-Specific CD8+ T Cells Associated with Reversible Immune Dysfunction

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Improved Survival with Ipilimumab in Patients with Metastatic Melanoma

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Autoimmune dilated cardiomyopathy in PD-1 receptor-deficient mice

7 April 2017

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Development of lupus-like autoimmune diseases by disruption of the PD-1 gene encoding an ITIM motif-carrying immunoreceptor

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The transcription factor BATF controls the global regulators of class-switch recombination in both B cells and T cells

7 April 2017

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Antigen load and viral sequence diversification determine the functional profile of HIV-1-specific CD8+ T cells

7 April 2017

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7 April 2017

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Follicular helper CD4 T cells (TFH)

7 April 2017

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Phase I study of single-agent anti-programmed death-1 (MDX-1106) in refractory solid tumors: safety, clinical activity, pharmacodynamics, and immunologic correlates

7 April 2017

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HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

7 April 2017

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PD-1 expression on HIV-specific T cells is associated with T-cell exhaustion and disease progression

7 April 2017

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Infliximab and methotrexate in the treatment of rheumatoid arthritis. Anti-Tumor Necrosis Factor Trial in Rheumatoid Arthritis with Concomitant Therapy Study Group

7 April 2017

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Cytokine storm in a phase 1 trial of the anti-CD28 monoclonal antibody TGN1412

7 April 2017

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Basic leucine zipper transcription factor, ATF-like (BATF) regulates epigenetically and energetically effector CD8 T-cell differentiation via Sirt1 expression

7 April 2017

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HIV controllers: a multifactorial phenotype of spontaneous viral suppression

27 September 2017

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HIV-mediated phosphatidylinositol 3-kinase/serine-threonine kinase activation in APCs leads to programmed death-1 ligand upregulation and suppression of HIV-specific CD8 T cells

27 September 2017

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Responsiveness of HIV-specific CD4 T cells to PD-1 blockade

27 September 2017

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HIV-specific CD4 T cells and immune control of viral replication

27 September 2017

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Intrinsic and extrinsic control of peripheral T-cell tolerance by costimulatory molecules of the CD28/ B7 family

27 September 2017

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Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection

27 September 2017

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Phenotype, function, and gene expression profiles of programmed death-1(hi) CD8 T cells in healthy human adults

27 September 2017

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High T-cell immune activation and immune exhaustion among individuals with suboptimal CD4 recovery after 4 years of antiretroviral therapy in an African cohort

27 September 2017

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Expression of PD-L1 and PD-L2 on human macrophages is up-regulated by HIV-1 and differentially modulated by IL-10

27 September 2017

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Acute depletion of activated memory B cells involves the PD-1 pathway in rapidly progressing SIV-infected macaques.

27 September 2017

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Transcriptional analysis of HIV-specific CD8+ T cells shows that PD-1 inhibits T cell function by upregulating BATF

27 September 2017

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Cooperation of Tim-3 and PD-1 in CD8 T-cell exhaustion during chronic viral infection

27 September 2017

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Elevated frequencies of highly activated CD4+ T cells in HIV+ patients developing immune reconstitution inflammatory syndrome

27 September 2017

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27 September 2017

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Immune exhaustion occurs concomitantly with immune activation and decrease in regulatory T cells in viremic chronically HIV-1-infected patients

27 September 2017

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Inflammatory cytokines as a third signal for T cell activation

27 September 2017

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T-cell exhaustion: characteristics, causes and conversion

27 September 2017

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Inhibitory TCR coreceptor PD-1 is a sensitive indicator of low-level replication of SIV and HIV-1

27 September 2017

1 reference

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Redefining chronic viral infection

27 September 2017

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PD-1 blockade in rhesus macaques: impact on chronic infection and prophylactic vaccination

27 September 2017

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Enhancing SIV-specific immunity in vivo by PD-1 blockade

27 September 2017

1 reference

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IL-10 and PD-L1 operate through distinct pathways to suppress T-cell activity during persistent viral infection

27 September 2017

1 reference

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Coregulation of CD8+ T cell exhaustion by multiple inhibitory receptors during chronic viral infection.

27 September 2017

1 reference

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Tim-3 expression defines a novel population of dysfunctional T cells with highly elevated frequencies in progressive HIV-1 infection

27 September 2017

1 reference

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PDL-1 upregulation on monocytes and T cells by HIV via type I interferon: restricted expression of type I interferon receptor by CCR5-expressing leukocytes

27 September 2017

1 reference

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Manipulating both the inhibitory and stimulatory immune system towards the success of therapeutic vaccination against chronic viral infections.

27 September 2017

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Phase I safety and pharmacokinetic study of CT-011, a humanized antibody interacting with PD-1, in patients with advanced hematologic malignancies

27 September 2017

1 reference

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27 September 2017

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27 September 2017

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SIV-specific CD8+ T cells express high levels of PD1 and cytokines but have impaired proliferative capacity in acute and chronic SIVmac251 infection

27 September 2017

1 reference

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Elevated expression levels of inhibitory receptor programmed death 1 on simian immunodeficiency virus-specific CD8 T cells during chronic infection but not after vaccination

27 September 2017

1 reference

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27 September 2017

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PD-1 up-regulation is correlated with HIV-specific memory CD8+ T-cell exhaustion in typical progressors but not in long-term nonprogressors

27 September 2017

1 reference

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PD-1 is a regulator of virus-specific CD8+ T cell survival in HIV infection

27 September 2017

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Upregulation of PD-1 expression on HIV-specific CD8+ T cells leads to reversible immune dysfunction

27 September 2017

1 reference

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T lymphocyte co-signaling pathways of the B7-CD28 family.

27 September 2017

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Co-inhibitory molecules of the B7-CD28 family in the control of T-cell immunity

27 September 2017

1 reference

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Turnover of lymphocytes and conceptual paradigms in HIV infection

27 September 2017

1 reference

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B-ATF functions as a negative regulator of AP-1 mediated transcription and blocks cellular transformation by Ras and Fos.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3731769

B-ATF: a novel human bZIP protein that associates with members of the AP-1 transcription factor family

27 September 2017

1 reference

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A new analysis of allogeneic interactions

27 September 2017

1 reference

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Dominant clonotypes within HIV-specific T cell responses are programmed death-1high and CD127low and display reduced variant cross-reactivity.

27 September 2017

1 reference

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Valganciclovir reduces T cell activation in HIV-infected individuals with incomplete CD4+ T cell recovery on antiretroviral therapy

30 May 2018

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Dynamic programmed death 1 expression by virus-specific CD8 T cells correlates with the outcome of acute hepatitis B.

30 May 2018

1 reference

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Upregulation of CTLA-4 by HIV-specific CD4+ T cells correlates with disease progression and defines a reversible immune dysfunction

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0106-4

Upregulation of PD-L1 on monocytes and dendritic cells by HIV-1 derived TLR ligands

21 January 2018

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0106-4

B7-H1 up-regulation impairs myeloid DC and correlates with disease progression in chronic HIV-1 infection

21 January 2018

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Low CD4+ T cell count is a risk factor for cardiovascular disease events in the HIV outpatient study

21 January 2018

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B7-H1 is up-regulated in HIV infection and is a novel surrogate marker of disease progression

21 January 2018

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Antiviral Intrahepatic T-Cell Responses Can Be Restored by Blocking Programmed Death-1 Pathway in Chronic Hepatitis B

21 January 2018

1 reference

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Programmed death 1 expression on HIV-specific CD4+ T cells is driven by viral replication and associated with T cell dysfunction

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22198819

12 December 2020

inferred from PubMed ID database lookup

Identification of PD-1 as a unique marker for failing immune reconstitution in HIV-1-infected patients on treatment

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/22198819

12 December 2020

inferred from PubMed ID database lookup

Purging the HIV-1 reservoir through the disruption of the PD-1 pathway.

1 reference

https://api.crossref.org/works/10.1007%2FS11904-011-0106-4

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1007/S11904-011-0106-4

0 references

Dimensions Publication ID

1027350666

0 references

Fatcat ID

release_iy4wjhndpjasnjddhj47hvej7q

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/iy4wjhndpjasnjddhj47hvej7q

24 November 2022