Mammalian mad2 and bub1/bubR1 recognize distinct spindle-attachment and kinetochore-tension checkpoints (Q24635263)

2

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F B Lacroix

3

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L Wilson

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R L Margolis

Proceedings of the National Academy of Sciences of the United States of America

5

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language of work or name

English

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publication date

10 April 2001

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published in

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volume

98

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issue

8

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page(s)

4492-7

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cites work

Human BUBR1 is a mitotic checkpoint kinase that monitors CENP-E functions at kinetochores and binds the cyclosome/APC

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Spindle checkpoint protein Xmad1 recruits Xmad2 to unattached kinetochores

7 April 2017

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Characterization of the kinetochore binding domain of CENP-E reveals interactions with the kinetochore proteins CENP-F and hBUBR1

7 April 2017

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The human homologue of Bub3 is required for kinetochore localization of Bub1 and a Mad3/Bub1-related protein kinase

7 April 2017

1 reference

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The checkpoint protein MAD2 and the mitotic regulator CDC20 form a ternary complex with the anaphase-promoting complex to control anaphase initiation

7 April 2017

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Mammalian p55CDC mediates association of the spindle checkpoint protein Mad2 with the cyclosome/anaphase-promoting complex, and is involved in regulating anaphase onset and late mitotic events

7 April 2017

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Mutations of mitotic checkpoint genes in human cancers

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Kinetochore fiber maturation in PtK1 cells and its implications for the mechanisms of chromosome congression and anaphase onset

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Identification of a human mitotic checkpoint gene: hsMAD2

7 April 2017

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The checkpoint delaying anaphase in response to chromosome monoorientation is mediated by an inhibitory signal produced by unattached kinetochores

7 April 2017

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S. cerevisiae genes required for cell cycle arrest in response to loss of microtubule function

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Feedback control of mitosis in budding yeast

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Identification of a vertebrate sister-chromatid separation inhibitor involved in transformation and tumorigenesis

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Association of spindle assembly checkpoint component XMAD2 with unattached kinetochores

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Chromosome missegregation and apoptosis in mice lacking the mitotic checkpoint protein Mad2

7 April 2017

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Localization of Mad2 to kinetochores depends on microtubule attachment, not tension

7 April 2017

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Kinetochore localization of murine Bub1 is required for normal mitotic timing and checkpoint response to spindle damage

7 April 2017

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Mitotic forces control a cell-cycle checkpoint

7 April 2017

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CENP-E forms a link between attachment of spindle microtubules to kinetochores and the mitotic checkpoint

7 April 2017

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The role of pre- and post-anaphase microtubules in the cytokinesis phase of the cell cycle

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The maize homologue of the cell cycle checkpoint protein MAD2 reveals kinetochore substructure and contrasting mitotic and meiotic localization patterns

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Microinjection of antibody to Mad2 protein into mammalian cells in mitosis induces premature anaphase

27 September 2017

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Tension-sensitive kinetochore phosphorylation and the chromosome distribution checkpoint in praying mantid spermatocytes.

27 September 2017

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Dynamic elastic behavior of alpha-satellite DNA domains visualized in situ in living human cells

27 September 2017

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Anaphase onset in vertebrate somatic cells is controlled by a checkpoint that monitors sister kinetochore attachment to the spindle

27 September 2017

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Microtubule dependency of p34cdc2 inactivation and mitotic exit in mammalian cells

27 September 2017

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Requirement of the spindle checkpoint for proper chromosome segregation in budding yeast meiosis

27 September 2017

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Polewards microtubule flux in the mitotic spindle: evidence from photoactivation of fluorescence

30 May 2018

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Mechanism of inhibition of cell proliferation by Vinca alkaloids.

30 May 2018

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Effects of vinblastine, podophyllotoxin and nocodazole on mitotic spindles. Implications for the role of microtubule dynamics in mitosis

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31862

30 May 2018

The spindle checkpoint

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.081076898

Mitotic block in HeLa cells by vinblastine: ultrastructural changes in kinetochore-microtubule attachment and in centrosomes.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=31862

Oscillating mitotic newt lung cell kinetochores are, on average, under tension and rarely push

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11274370

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Tension on chromosomes increases the number of kinetochore microtubules but only within limits

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/11274370

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.081076898

1 reference

4117002

ADS bibcode

2001PNAS...98.4492S

0 references

4117002

1 reference

1 reference

1 reference