Single-molecule studies reveal dynamics of DNA unwinding by the ring-shaped T7 helicase (Q24642351)

1

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Lu Bai

2

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Benjamin Y Smith

3

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Smita S Patel

DINAMelt web server for nucleic acid melting prediction

4

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language of work or name

English

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publication date

29 June 2007

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published in

Cell

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volume

129

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issue

7

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page(s)

1299-309

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cites work

1 reference

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UvrD helicase unwinds DNA one base pair at a time by a two-part power stroke

7 April 2017

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RNA translocation and unwinding mechanism of HCV NS3 helicase and its coordination by ATP

7 April 2017

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Crystal structure of T7 gene 4 ring helicase indicates a mechanism for sequential hydrolysis of nucleotides

7 April 2017

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Crystal structure of the helicase domain from the replicative helicase-primase of bacteriophage T7

7 April 2017

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Crystal structures of complexes of PcrA DNA helicase with a DNA substrate indicate an inchworm mechanism

7 April 2017

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Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwinding

7 April 2017

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Crystal structure of RecBCD enzyme reveals a machine for processing DNA breaks

7 April 2017

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A molecular throttle: the recombination hotspot chi controls DNA translocation by the RecBCD helicase

7 April 2017

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RecBCD enzyme is a DNA helicase with fast and slow motors of opposite polarity

7 April 2017

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Mechanism of DNA translocation in a replicative hexameric helicase

7 April 2017

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DNA primase acts as a molecular brake in DNA replication

27 September 2017

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Autoinhibition of Escherichia coli Rep monomer helicase activity by its 2B subdomain

27 September 2017

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Opening of nucleic-acid double strands by helicases: active versus passive opening.

27 September 2017

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The DNA-unwinding mechanism of the ring helicase of bacteriophage T7.

27 September 2017

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Single-molecule assay reveals strand switching and enhanced processivity of UvrD

27 September 2017

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Forward and reverse motion of single RecBCD molecules on DNA.

27 September 2017

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27 September 2017

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Helicase mechanisms and the coupling of helicases within macromolecular machines. Part I: Structures and properties of isolated helicases

27 September 2017

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Laser-induced heating in optical traps

27 September 2017

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The 2B domain of the Escherichia coli Rep protein is not required for DNA helicase activity

27 September 2017

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Single molecule analysis of RNA polymerase elongation reveals uniform kinetic behavior

27 September 2017

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Probing protein-DNA interactions by unzipping a single DNA double helix

27 September 2017

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Vinylphosphonate internucleotide linkages inhibit the activity of PcrA DNA helicase.

27 September 2017

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Modularity and specialization in superfamily 1 and 2 helicases

27 September 2017

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A general model for nucleic acid helicases and their "coupling" within macromolecular machines

27 September 2017

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Unwinding the 'Gordian knot' of helicase action.

27 September 2017

1 reference

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Structure and function of hexameric helicases.

27 September 2017

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Uncoupling DNA translocation and helicase activity in PcrA: direct evidence for an active mechanism.

27 September 2017

1 reference

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A hexameric helicase encircles one DNA strand and excludes the other during DNA unwinding

27 September 2017

1 reference

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Mechanisms of helicase-catalyzed DNA unwinding

27 September 2017

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Overstretching B-DNA: the elastic response of individual double-stranded and single-stranded DNA molecules

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699903

Oligomeric structure of bacteriophage T7 DNA primase/helicase proteins.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699903

Bacteriophage T7 helicase/primase proteins form rings around single-stranded DNA that suggest a general structure for hexameric helicases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699903

A physical model for the translocation and helicase activities of Escherichia coli transcription termination protein Rho

27 September 2017

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Template recognition sequence for RNA primer synthesis by gene 4 protein of bacteriophage T7

27 September 2017

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The gene 4 protein of bacteriophage T7. Characterization of helicase activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699903

DNA synthesis provides the driving force to accelerate DNA unwinding by a helicase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699903

Mechanism of ATP-dependent translocation of E.coli UvrD monomers along single-stranded DNA.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699903

Energy flow considerations and thermal fluctuational opening of DNA base pairs at a replicating fork: unwinding consistent with observed replication rates

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699903

Large scale purification and biochemical characterization of T7 primase/helicase proteins. Evidence for homodimer and heterodimer formation

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699903

Probing SWI/SNF remodeling of the nucleosome by unzipping single DNA molecules.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699903

Repetitive shuttling of a motor protein on DNA.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699903

Twin DNA Pumps of a Hexameric Helicase Provide Power to Simultaneously Melt Two Duplexes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699903

A motor that makes its own track: helicase unwinding of DNA.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699903

RecBCD enzyme is a bipolar DNA helicase

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699903

A Dimer of Escherichia coli UvrD is the active form of the helicase in vitro

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699903

T7 DNA helicase: a molecular motor that processively and unidirectionally translocates along single-stranded DNA.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699903

Molecular mechanisms of the functional coupling of the helicase (gp41) and polymerase (gp43) of bacteriophage T4 within the DNA replication fork

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699903

Demonstration of unidirectional single-stranded DNA translocation by PcrA helicase: measurement of step size and translocation speed

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699903

Asymmetric interactions of hexameric bacteriophage T7 DNA helicase with the 5'- and 3'-tails of the forked DNA substrate.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699903

Bacteriophage T7: minimal requirements for the replication of a duplex DNA molecule.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2699903

χ-Sequence recognition and DNA translocation by single RecBCD helicase/nuclease molecules

28 November 2018

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12 December 2020

DNA-dependent nucleoside 5'-triphosphatase activity of the gene 4 protein of bacteriophage T7

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12 December 2020

Allosteric effects of nucleotide cofactors on Escherichia coli Rep helicase-DNA binding

1 reference

12 December 2020

Escherichia coli rep helicase unwinds DNA by an active mechanism

1 reference

12 December 2020

10.1016/J.CELL.2007.04.038

Identifiers

DOI

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2689787

2689787

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1 reference

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