Structure-activity relationship studies of the two-component lantibiotic haloduracin (Q24642730)

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24 December 2019

title

Structure-activity relationship studies of the two-component lantibiotic haloduracin (English)

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24 December 2019

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4

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24 December 2019

author name string

Lisa E Cooper

series ordinal

1

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24 December 2019

Amanda L McClerren

series ordinal

2

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24 December 2019

Anita Chary

series ordinal

3

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24 December 2019

language of work or name

English

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publication date

1 October 2008

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24 December 2019

published in

Chemistry and Biology

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24 December 2019

volume

15

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24 December 2019

issue

10

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24 December 2019

page(s)

1035-1045

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NMR study of mersacidin and lipid II interaction in dodecylphosphocholine micelles. Conformational changes are a key to antimicrobial activity

24 December 2019

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27 September 2017

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The leader peptide is not required for post-translational modification by lacticin 481 synthetase

27 September 2017

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27 September 2017

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Mutants of the zinc ligands of lacticin 481 synthetase retain dehydration activity but have impaired cyclization activity.

27 September 2017

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Discovery and in vitro biosynthesis of haloduracin, a two-component lantibiotic

27 September 2017

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Lacticin 481 synthetase phosphorylates its substrate during lantibiotic production

27 September 2017

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Streptococcus rattus strain BHT produces both a class I two-component lantibiotic and a class II bacteriocin

27 September 2017

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Sequential actions of the two component peptides of the lantibiotic lacticin 3147 explain its antimicrobial activity at nanomolar concentrations

27 September 2017

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27 September 2017

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Genetic analysis of a unique bacteriocin, Smb, produced by Streptococcus mutans GS5

27 September 2017

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Enterococcal cytolysin: a novel two component peptide system that serves as a bacterial defense against eukaryotic and prokaryotic cells

27 September 2017

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27 September 2017

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Lacticin 481: in vitro reconstitution of lantibiotic synthetase activity

27 September 2017

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Construction of an expression system for site-directed mutagenesis of the lantibiotic mersacidin

27 September 2017

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Two-peptide bacteriocins produced by lactic acid bacteria

27 September 2017

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Plantaricin W from Lactobacillus plantarum belongs to a new family of two-peptide lantibiotics

27 September 2017

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Effect of amino acid substitutions in conserved residues in the leader peptide on biosynthesis of the lantibiotic mutacin II.

27 September 2017

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Structure-activity study of the lantibiotic mutacin II from Streptococcus mutans T8 by a gene replacement strategy

27 September 2017

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The lantibiotic mersacidin inhibits peptidoglycan synthesis by targeting lipid II.

27 September 2017

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Applications of the bacteriocin, nisin

27 September 2017

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Protein engineering of lantibiotics.

27 September 2017

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Novel lantibiotics and their pre-peptides

27 September 2017

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Engineering of a novel thioether bridge and role of modified residues in the lantibiotic Pep5.

27 September 2017

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Isolation and characterization of genetically engineered gallidermin and epidermin analogs.

27 September 2017

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A family of bacteriocin ABC transporters carry out proteolytic processing of their substrates concomitant with export

27 September 2017

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27 September 2017

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Determining the structure and mode of action of microbisporicin, a potent lantibiotic active against multiresistant pathogens.

27 September 2017

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Identification of essential catalytic residues of the cyclase NisC involved in the biosynthesis of nisin.

28 November 2018

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Complete alanine scanning of the two-component lantibiotic lacticin 3147: generating a blueprint for rational drug design.

28 November 2018

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Engineering dehydro amino acids and thioethers into peptides using lacticin 481 synthetase.

28 November 2018

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Structure and mechanism of the lantibiotic cyclase involved in nisin biosynthesis.

28 November 2018

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Lantibiotic structures as guidelines for the design of peptides that can be modified by lantibiotic enzymes.

28 November 2018

1 reference

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Mersacidin eradicates methicillin-resistant Staphylococcus aureus (MRSA) in a mouse rhinitis model.

28 November 2018

1 reference

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Structural characterization of lacticin 3147, a two-peptide lantibiotic with synergistic activity.

28 November 2018

1 reference

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Activation of subtilin precursors by Bacillus subtilis extracellular serine proteases subtilisin (AprE), WprA, and Vpr

28 November 2018

1 reference

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The roles of thiols in the bacterial organomercurial lyase (MerB).

28 November 2018

1 reference

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Lacticin 3147 displays activity in buffer against gram-positive bacterial pathogens which appear insensitive in standard plate assays.

28 November 2018

1 reference

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Extensive post-translational modification, including serine to D-alanine conversion, in the two-component lantibiotic, lacticin 3147

28 November 2018

1 reference

12 December 2020

Engineering a disulfide bond and free thiols in the lantibiotic nisin Z

1 reference

12 December 2020

A system for the random mutagenesis of the two-peptide lantibiotic lacticin 3147: analysis of mutants producing reduced antibacterial activities

1 reference

12 December 2020

Influence of amino acid substitutions in the nisin leader peptide on biosynthesis and secretion of nisin by Lactococcus lactis

1 reference

12 December 2020

The tetracyclic lantibiotic actagardine. 1H-NMR and 13C-NMR assignments and revised primary structure

1 reference

12 December 2020

The mode of action of the lantibiotic lacticin 3147--a complex mechanism involving specific interaction of two peptides and the cell wall precursor lipid II

1 reference

12 December 2020

Purification and functional studies of a potent modified quorum-sensing peptide and a two-peptide bacteriocin in Streptococcus mutans

1 reference

12 December 2020

Identification of a novel two-peptide lantibiotic, haloduracin, produced by the alkaliphile Bacillus halodurans C-125

1 reference

12 December 2020

10.1016/J.CHEMBIOL.2008.07.020

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DOI

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18940665%20AND%20SRC:MED&resulttype=core&format=json

24 December 2019

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24 December 2019

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