Molecular physiology of weight regulation in mice and humans (Q24644070)

International Journal of Obesity

Europe PubMed Central

title

Molecular physiology of weight regulation in mice and humans (English)

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R L Leibel

1

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language of work or name

English

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publication date

December 2008

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published in

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volume

32 Suppl 7

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page(s)

S98-108

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cites work

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Low-dose leptin reverses skeletal muscle, autonomic, and neuroendocrine adaptations to maintenance of reduced weight

27 September 2017

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Neurogenesis in the hypothalamus of adult mice: potential role in energy balance

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How can drug addiction help us understand obesity?

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A primer on diffusion tensor imaging of anatomical substructures

27 September 2017

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Trophic action of leptin on hypothalamic neurons that regulate feeding

27 September 2017

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Hypothalamic control of food intake in rats and cats

27 September 2017

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The role of depot fat in the hypothalamic control of food intake in the rat.

27 September 2017

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The role of leptin in the control of body weight

27 September 2017

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Pooling analysis of genetic data: the association of leptin receptor (LEPR) polymorphisms with variables related to human adiposity

27 September 2017

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Successful weight loss maintenance

27 September 2017

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The regulation of total body fat: lessons learned from lipectomy studies

27 September 2017

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Identification of SOCS-3 as a potential mediator of central leptin resistance

27 September 2017

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Heterozygosity for Lep(ob) or Lep(rdb) affects body composition and leptin homeostasis in adult mice.

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

The molecular basis of the obese mutation in ob2J mice

27 September 2017

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Attenuation of the obesity syndrome of ob/ob mice by the loss of neuropeptide Y.

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Effects of gender, body composition, and menopause on plasma concentrations of leptin.

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Mapping of the OB receptor to 1p in a region of nonconserved gene order from mouse and rat to human

27 September 2017

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The human obese (OB) gene: RNA expression pattern and mapping on the physical, cytogenetic, and genetic maps of chromosome 7.

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Phenotypes of mouse diabetes and rat fatty due to mutations in the OB (leptin) receptor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Regional adiposity and morbidity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

A polymorphic DNA marker genetically linked to Huntington's disease

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

DNA linkage analysis of X chromosome-linked chronic granulomatous disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Brown adipose tissue metabolism and thermogenesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Specific cloning of DNA fragments absent from the DNA of a male patient with an X chromosome deletion

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Rat obesity gene fatty (fa) maps to chromosome 5: evidence for homology with the mouse gene diabetes (db).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Molecular mapping of the mouse ob mutation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Molecular mapping of mouse chromosomes 4 and 6: Use of a flow-sorted robertsonian chromosome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Dietary obesity in nine inbred mouse strains

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Manifestations of hypothalamic obesity in man: a comprehensive investigation of eight patients and a reveiw of the literature

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Obese and diabetes: Two mutant genes causing diabetes-obesity syndromes in mice

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Involvement of a humoral factor in regulation of body weight in parabiotic rats

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Genetic influences on the response of body fat and fat distribution to positive and negative energy balances in human identical twins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Leptin regulation of Agrp and Npy mRNA in the rat hypothalamus

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Neuroscience and appetitive behavior research: 25 years

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Phenotype of the obese Koletsky (f) rat due to Tyr763Stop mutation in the extracellular domain of the leptin receptor (Lepr): evidence for deficient plasma-to-CSF transport of leptin in both the Zucker and Koletsky obese rat.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Changes in energy expenditure resulting from altered body weight.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Sustained intracerebroventricular infusion of brain fuels reduces body weight and food intake in rats.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Metabolic hormones and regulation of body weight.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Alterations in adipocyte free fatty acid re-esterification associated with obesity and weight reduction in man.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Reduced rate of energy expenditure as a risk factor for body-weight gain

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Energy expenditure by doubly labeled water: validation in humans and proposed calculation.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Discrepancy between self-reported and actual caloric intake and exercise in obese subjects.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Relationship between plasma and cerebrospinal fluid insulin levels of dogs

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

A biologic radar system for the assessment of body mass the model of a geometry sensitive endocrine system is presented

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Surgical removal of adipose tissue alters feeding behavior and the development of obesity in rats

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates.

30 May 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.245

Stages of recovery and development of lateral hypothalamic control of food and water intake.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.245

The effects of lesions in the hypothalamus in parabiotic rats.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.245

Genetic map of rat chromosome 5 including the fatty (fa) locus.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.245

Effects of experimental weight perturbation on skeletal muscle work efficiency in human subjects

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.245

Recombinant leptin for weight loss in obese and lean adults: a randomized, controlled, dose-escalation trial.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.245

Synergy of sibutramine and low-dose leptin in treatment of diet-induced obesity in rats

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.245

Is the energy homeostasis system inherently biased toward weight gain?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.245

Neuroscience. Regulating energy balance: the substrate strikes back.

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.245

Partial leptin deficiency and human adiposity.

21 January 2018

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https://api.crossref.org/works/10.1038%2FIJO.2008.245

What is the optimal threshold for cerebral perfusion pressure following traumatic brain injury?

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.245

Effects of gender, body composition, and menopause on plasma concentrations of leptin

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FIJO.2008.245

Long-term persistence of adaptive thermogenesis in subjects who have maintained a reduced body weight

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Effects of a high-protein ketogenic diet on hunger, appetite, and weight loss in obese men feeding ad libitum.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Phenotype of fatty due to Gln269Pro mutation in the leptin receptor (Lepr).

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Regulation of food intake and body weight by insulin.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2682360

Regulation of Energy Balance

28 November 2018

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https://api.crossref.org/works/10.1038%2FIJO.2008.245

Effects of parabiosis of obese with diabetes and normal mice

21 January 2018

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12 December 2020

Changes in the distribution of body mass index of adults and children in the US population

1 reference

12 December 2020

The role of leptin in human physiology

1 reference

12 December 2020

Body composition of lean and obese Zucker rats in parabiosis

1 reference

12 December 2020

Genetic parameters and trends for lean growth rate and its comvonents in U.S. Yorkshire, Duroc, Hampshire, and Landrace pigs

1 reference

12 December 2020

Genetic architecture of growth and body composition in unique chicken populations

1 reference

12 December 2020

Body weight gain in free-living Pima Indians: effect of energy intake vs expenditure

1 reference

12 December 2020

Diminished energy requirements in reduced-obese patients

1 reference

12 December 2020

The response to long-term overfeeding in identical twins

1 reference

12 December 2020

Molecular genetic linkage maps of mouse chromosomes 4 and 6

1 reference

12 December 2020

Mechanisms of increased lipoprotein lipase in fat cells of obese Zucker rats

1 reference

12 December 2020

Endocrine and metabolic effects of experimental obesity in man

1 reference

12 December 2020

Identifiers

DOI

10.1038/IJO.2008.245

1 reference

Dimensions Publication ID

2997357

1042231886

0 references

2997357

1 reference

1 reference

1 reference