Suberoylanilide hydroxamic acid reactivates HIV from latently infected cells (Q24644201)

1

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Marc Schweneker

2

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Ching-Shih Chen

3

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Joseph M McCune

4

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Jeffrey Martin

6

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B Matija Peterlin

Journal of Biological Chemistry

7

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language of work or name

English

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publication date

13 March 2009

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published in

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volume

284

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issue

11

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page(s)

6782-9

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cites work

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Analysis of the large inactive P-TEFb complex indicates that it contains one 7SK molecule, a dimer of HEXIM1 or HEXIM2, and two P-TEFb molecules containing Cdk9 phosphorylated at threonine 186

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Constitutive activation of signal transducers and activators of transcription predicts vorinostat resistance in cutaneous T-cell lymphoma

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PP2B and PP1alpha cooperatively disrupt 7SK snRNP to release P-TEFb for transcription in response to Ca2+ signaling

27 September 2017

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HIV-induced changes in T cell signaling pathways

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Decay dynamics of HIV-1 depend on the inhibited stages of the viral life cycle

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Histone hyperacetylation occurs on promoters of lytic cycle regulatory genes in Epstein-Barr virus-infected cell lines which are refractory to disruption of latency by histone deacetylase inhibitors

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HMBA releases P-TEFb from HEXIM1 and 7SK snRNA via PI3K/Akt and activates HIV transcription

27 September 2017

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Tat competes with HEXIM1 to increase the active pool of P-TEFb for HIV-1 transcription.

27 September 2017

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27 September 2017

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Modulation of a P-TEFb functional equilibrium for the global control of cell growth and differentiation

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Suberoylanilide hydroxamic acid induces Akt-mediated phosphorylation of p300, which promotes acetylation and transcriptional activation of RelA/p65.

27 September 2017

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Hexamethylbisacetamide remodels the human immunodeficiency virus type 1 (HIV-1) promoter and induces Tat-independent HIV-1 expression but blunts cell activation

27 September 2017

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IL-7 as a potential therapy for HIV-1-infected individuals

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27 September 2017

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The transcriptional inhibitors, actinomycin D and alpha-amanitin, activate the HIV-1 promoter and favor phosphorylation of the RNA polymerase II C-terminal domain

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Hexamethylene bisacetamide induces programmed cell death (apoptosis) and down-regulates BCL-2 expression in human myeloma cells

27 September 2017

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27 September 2017

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27 September 2017

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