SIRT3 is a stress-responsive deacetylase in cardiomyocytes that protects cells from stress-mediated cell death by deacetylation of Ku70 (Q24645120)

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Sadhana A Samant

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Vinodkumar B Pillai

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Senthilkumar B Rajamohan

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Mahesh P Gupta

Molecular and Cellular Biology

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language of work or name

English

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publication date

October 2008

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published in

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volume

28

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page(s)

6384-401

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issue

20

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cites work

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SIRT3, a human SIR2 homologue, is an NAD-dependent deacetylase localized to mitochondria

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Mammalian Sir2 homolog SIRT3 regulates global mitochondrial lysine acetylation

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Poly(ADP-ribose) polymerase-1-dependent cardiac myocyte cell death during heart failure is mediated by NAD+ depletion and reduced Sir2alpha deacetylase activity

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SIRT3, a mitochondrial sirtuin deacetylase, regulates mitochondrial function and thermogenesis in brown adipocytes

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Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

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Sirtuins: critical regulators at the crossroads between cancer and aging

27 September 2017

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Aging hematopoietic stem cells decline in function and exhibit epigenetic dysregulation

27 September 2017

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Analysis of apoptosis by propidium iodide staining and flow cytometry

27 September 2017

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27 September 2017

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A novel VNTR enhancer within the SIRT3 gene, a human homologue of SIR2, is associated with survival at oldest ages.

27 September 2017

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27 September 2017

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Regulation of cardiac myocyte cell death

27 September 2017

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Human Sir2 and the 'silencing' of p53 activity

27 September 2017

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The transcriptional co-activators CBP and p300 are activated via phenylephrine through the p42/p44 MAPK cascade

27 September 2017

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27 September 2017

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Sequential activation of poly(ADP-ribose) polymerase 1, calpains, and Bax is essential in apoptosis-inducing factor-mediated programmed necrosis.

27 September 2017

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Sirt1 regulates aging and resistance to oxidative stress in the heart

30 May 2018

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Acetylation of the C terminus of Ku70 by CBP and PCAF controls Bax-mediated apoptosis

28 November 2018

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Inhibition of cardiac myocyte apoptosis improves cardiac function and abolishes mortality in the peripartum cardiomyopathy of Galpha(q) transgenic mice

28 November 2018

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Variability of the SIRT3 gene, human silent information regulator Sir2 homologue, and survivorship in the elderly

28 November 2018

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STRUCTURE AND MASS OF MITOCHONDRIA IN THE PROCESS OF COMPENSATORY HYPERFUNCTION AND HYPERTROPHY OF THE HEART

28 November 2018

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