Effect of interleukin-1beta on osteogenic protein 1-induced signaling in adult human articular chondrocytes (Q24649140)

2

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Lev Rappoport

3

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David C Rueger

4

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Susan Chubinskaya

TGF-beta signal transduction

5

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language of work or name

English

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publication date

January 2009

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published in

Arthritis & Rheumatology

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volume

60

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issue

1

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page(s)

143-54

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cites work

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NF-kappa B mediates the stimulation of cytokine and chemokine expression by human articular chondrocytes in response to fibronectin fragments

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CD44 modulates Smad1 activation in the BMP-7 signaling pathway

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TGF beta receptor internalization into EEA1-enriched early endosomes: role in signaling to Smad2

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TbetaRI phosphorylation of Smad2 on Ser465 and Ser467 is required for Smad2-Smad4 complex formation and signaling

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Selective activation of the mitogen-activated protein kinase subgroups c-Jun NH2 terminal kinase and p38 by IL-1 and TNF in human articular chondrocytes

28 September 2017

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Interleukin-1 activates a novel protein kinase cascade that results in the phosphorylation of Hsp27.

28 September 2017

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Signal transduction via serine/threonine kinase receptors

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IGF-I stimulation of proteoglycan synthesis by chondrocytes requires activation of the PI 3-kinase pathway but not ERK MAPK.

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Stimulation of BMP-2 expression by pro-inflammatory cytokines IL-1 and TNF-alpha in normal and osteoarthritic chondrocytes

30 May 2018

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IL-1-induced nitric oxide inhibits chondrocyte proliferation via PGE2.

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Signal transduction of the TGF-beta superfamily by Smad proteins

30 May 2018

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Crossref

https://api.crossref.org/works/10.1002%2FART.24151

Shedding of a soluble form of BMP receptor-IB controls bone cell responses to BMP.

21 January 2018

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Bone morphogenetic protein and transforming growth factor beta inhibitory Smads 6 and 7 are expressed in human adult normal and osteoarthritic cartilage in vivo and are differentially regulated in vitro by interleukin-1beta.

28 November 2018

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Osteogenic Protein-1 inhibits matrix depletion in a hyaluronan hexasaccharide-induced model of osteoarthritis

28 November 2018

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Modulation of endogenous osteogenic protein-1 (OP-1) by interleukin-1 in adult human articular cartilage.

28 November 2018

1 reference

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Alterations in endogenous osteogenic protein-1 with degeneration of human articular cartilage.

28 November 2018

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Distinct endocytic pathways regulate TGF-β receptor signalling and turnover

28 November 2018

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Nuclear exclusion of Smad2 is a mechanism leading to loss of competence

28 November 2018

1 reference

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Osteogenic protein-1 (OP-1) blocks cartilage damage caused by fibronectin fragments and promotes repair by enhancing proteoglycan synthesis.

28 November 2018

1 reference

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Chondrocyte cytokine and growth factor expression in murine osteoarthritis.

28 November 2018

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Smad6 inhibits signalling by the TGF-beta superfamily

28 November 2018

1 reference

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Cytokine regulation of chondrocyte functions

28 November 2018

1 reference

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Quantification of 35S-labeled proteoglycans complexed to alcian blue by rapid filtration in multiwell plates.

28 November 2018

1 reference

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Osteogenic protein 1 stimulates cells-associated matrix assembly by normal human articular chondrocytes: up-regulation of hyaluronan synthase, CD44, and aggrecan

28 November 2018

1 reference

12 December 2020

Induction of osteogenic protein-1 expression by interleukin-1beta in cultured rabbit articular chondrocytes

1 reference

12 December 2020

1 reference

12 December 2020

Induction of aggrecanase 1 (ADAM-TS4) by interleukin-1 occurs through activation of constitutively produced protein

1 reference

12 December 2020

Bone morphogenetic protein-7 inhibits constitutive and interleukin-1 beta-induced monocyte chemoattractant protein-1 expression in human mesangial cells: role for JNK/AP-1 pathway

1 reference

12 December 2020

Modulation of interleukin-1–induced alterations in cartilage proteoglycan metabolism by activation of protein kinase C

1 reference

12 December 2020

Identification of type I receptors for osteogenic protein-1 and bone morphogenetic protein-4

1 reference

12 December 2020

Interleukin-1 modulates phosphorylation of proteins in human osteoblastic cells

1 reference

12 December 2020

Recombinant human osteogenic protein 1 is a potent stimulator of the synthesis of cartilage proteoglycans and collagens by human articular chondrocytes

1 reference

12 December 2020

Effects of recombinant human osteogenic protein 1 on the production of proteoglycan, prostaglandin E2, and interleukin-1 receptor antagonist by human articular chondrocytes cultured in the presence of interleukin-1beta

1 reference

12 December 2020

Activation of specific MEK-ERK cascade is necessary for TGFbeta signaling and crosstalk with PKA and PKC pathways in cultured rat articular chondrocytes

1 reference

12 December 2020

Identifiers

DOI

10.1002/ART.24151

1 reference

1 reference

1 reference

PubMed publication ID

19116903

1 reference