NinaB combines carotenoid oxygenase and retinoid isomerase activity in a single polypeptide (Q24650113)

Neither inactivation nor afterpotential B Dmel_CG9347

ChEBI release 2020-05-28

ChEBI ID

66898

1 reference

(1R)-4-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(4R)-4-hydroxy-2,6,6-trimethylcyclohex-2-en-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-3,5,5-trimethylcyclohex-3-en-1-ol

GOA release 2020-03-11

1 reference

1 reference

1 reference

1 reference

1 reference

4

Johannes von Lintig

Johannes

von Lintig

1 reference

19 October 2023

Vitus Oberhauser

1

Vitus

Oberhauser

1 reference

19 October 2023

Olaf Voolstra

series ordinal

2

author given names

Olaf

author last names

Voolstra

1 reference

19 October 2023

Annette Bangert

series ordinal

3

author given names

Annette

author last names

Bangert

1 reference

19 October 2023

Klaus Vogt

series ordinal

5

author given names

Klaus

author last names

Vogt

1 reference

19 October 2023

language of work or name

English

0 references

publication date

2 December 2008

0 references

full work available at URL

https://europepmc.org/articles/pmc2596218?pdf=render

1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1073/pnas.0807805105?email=unpaywall_01@example.com

published in

Proceedings of the National Academy of Sciences of the United States of America

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volume

105

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issue

48

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page(s)

19000-5

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1 reference

19 March 2024

https://api.unpaywall.org/v2/10.1073/pnas.0807805105?email=unpaywall_01@example.com

access restriction status

open access

1 reference

inferred from online access status

cites work

RPE65 is the isomerohydrolase in the retinoid visual cycle

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

Cloning and characterization of a human beta,beta-carotene-15,15'-dioxygenase that is highly expressed in the retinal pigment epithelium

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

Identification and characterization of a mammalian enzyme catalyzing the asymmetric oxidative cleavage of provitamin A

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

Energy conservation in chemotrophic anaerobic bacteria

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

Rpe65 is the retinoid isomerase in bovine retinal pigment epithelium

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

The structure of a retinal-forming carotenoid oxygenase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

Steady-state enzyme kinetics with high-affinity substrates or inhibitors. A statistical treatment of dose-response curves

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

Identification, expression, and substrate specificity of a mammalian beta-carotene 15,15'-dioxygenase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

Cloning and expression of beta,beta-carotene 15,15'-dioxygenase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

Structural and biological aspects of carotenoid cleavage

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

G protein-coupled receptor rhodopsin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

The biochemical characterization of ferret carotene-9',10'-monooxygenase catalyzing cleavage of carotenoids in vitro and in vivo

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

Mutation of key residues of RPE65 abolishes its enzymatic role as isomerohydrolase in the visual cycle.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

Towards a better understanding of carotenoid metabolism in animals

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

Retinal biosynthesis in Eubacteria: in vitro characterization of a novel carotenoid oxygenase from Synechocystis sp. PCC 6803.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

Thermal activation and photoactivation of visual pigments.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

Demonstration of a sensory rhodopsin in eubacteria

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

A class B scavenger receptor mediates the cellular uptake of carotenoids in Drosophila

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

Filling the gap in vitamin A research. Molecular identification of an enzyme cleaving beta-carotene to retinal

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

The metabolic pathway of visual pigment chromophore formation in Drosophila melanogaster--all-trans (3S)-3-hydroxyretinal is formed from all-trans retinal via (3R)-3-hydroxyretinal in the dark

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

Specific oxidative cleavage of carotenoids by VP14 of maize

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

Flies in the group Cyclorrhapha use (3S)-3-hydroxyretinal as a unique visual pigment chromophore

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

Dependency on light and vitamin A derivatives of the biogenesis of 3-hydroxyretinal and visual pigment in the compound eyes of Drosophila melanogaster

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

Biochemical properties of purified recombinant human beta-carotene 15,15'-monooxygenase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

A fly, Drosophila melanogaster, forms 11-cis 3-hydroxyretinal in the dark.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

Rpe65 is necessary for production of 11-cis-vitamin A in the retinal visual cycle.

30 May 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0807805105

Maturation of major Drosophila rhodopsin, ninaE, requires chromophore 3-hydroxyretinal

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0807805105

Rescue of photoreceptor degeneration in rhodopsin-null Drosophila mutants by activated Rac1.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0807805105

Quantum yield of CHAPSO-solubilized rhodopsin and 3-hydroxy retinal containing bovine opsin.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0807805105

Alpha-retinals as rhodopsin chromophores--preference for the 9-Z configuration and partial agonist activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1073%2FPNAS.0807805105

The Drosophila class B scavenger receptor NinaD-I is a cell surface receptor mediating carotenoid transport for visual chromophore synthesis.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

Rhodopsin plays an essential structural role in Drosophila photoreceptor development.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2596218

Analysis of the blind Drosophila mutant ninaB identifies the gene encoding the key enzyme for vitamin A formation invivo

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19020100

12 December 2020

inferred from PubMed ID database lookup

Enzymic parameters: Measurement of V and Km

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19020100

12 December 2020

inferred from PubMed ID database lookup

Biochemical characterization of the retinoid isomerase system of the eye

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19020100

12 December 2020