Comparison of citrus coumarins on carcinogen-detoxifying enzymes in Nrf2 knockout mice (Q24651150)

2

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Asper Childers

3

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Ken Itoh

4

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Masayuki Yamamoto

5

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Heather E Kleiner

Mechanistic studies of the Nrf2-Keap1 signaling pathway

6

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language of work or name

English

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publication date

28 March 2009

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published in

Toxicology Letters

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volume

185

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issue

3

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page(s)

180-6

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cites work

1 reference

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Direct evidence that sulfhydryl groups of Keap1 are the sensors regulating induction of phase 2 enzymes that protect against carcinogens and oxidants

7 April 2017

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An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

7 April 2017

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The antioxidant responsive element. Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity

7 April 2017

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Glutathione S-transferases. The first enzymatic step in mercapturic acid formation

7 April 2017

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A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding

7 April 2017

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Cancer chemoprevention with dietary phytochemicals

7 April 2017

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The glutathione S-transferase supergene family: regulation of GST and the contribution of the isoenzymes to cancer chemoprotection and drug resistance

7 April 2017

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Effects of naturally occurring coumarins on hepatic drug-metabolizing enzymes in mice

7 April 2017

1 reference

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Pro-apoptotic effects of 1'-acetoxychavicol acetate in human breast carcinoma cells

28 September 2017

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Cancer chemoprevention by phytochemicals: potential molecular targets, biomarkers and animal models

28 September 2017

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Mechanism of action of sulforaphane: inhibition of p38 mitogen-activated protein kinase isoforms contributing to the induction of antioxidant response element-mediated heme oxygenase-1 in human hepatoma HepG2 cells

28 September 2017

1 reference

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Naturally occurring coumarins inhibit 7,12-dimethylbenz[a]anthracene DNA adduct formation in mouse mammary gland

28 September 2017

1 reference

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Naturally occurring coumarins inhibit human cytochromes P450 and block benzo[a]pyrene and 7,12-dimethylbenz[a]anthracene DNA adduct formation in MCF-7 cells

28 September 2017

1 reference

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Oral administration of the citrus coumarin, isopimpinellin, blocks DNA adduct formation and skin tumor initiation by 7,12-dimethylbenz[a]anthracene in SENCAR mice

28 September 2017

1 reference

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Oral administration of naturally occurring coumarins leads to altered phase I and II enzyme activities and reduced DNA adduct formation by polycyclic aromatic hydrocarbons in various tissues of SENCAR mice

28 September 2017

1 reference

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Development of a green fluorescent protein microplate assay for the screening of chemopreventive agents

28 September 2017

1 reference

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In vitro absorption and metabolism of a citrus chemopreventive agent, auraptene, and its modifying effects on xenobiotic enzyme activities in mouse livers

28 September 2017

1 reference

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Characterization and partial purification of microsomal NAD(P)H:quinone oxidoreductases

28 September 2017

1 reference

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Regulation of glutathione S-transferase Ya subunit gene expression: identification of a unique xenobiotic-responsive element controlling inducible expression by planar aromatic compounds

28 September 2017

1 reference

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Role of cytochrome P450 1a1 and 1b1 in the metabolic activation of 7,12-dimethylbenz[a]anthracene and the effects of naturally occurring furanocoumarins on skin tumor initiation

28 September 2017

1 reference

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Purification and characterization of two isofunctional forms of NAD(P)H: quinone reductase from mouse liver

30 May 2018

1 reference

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Transcriptional regulation of the rat glutathione S-transferase Ya subunit gene. Characterization of a xenobiotic-responsive element controlling inducible expression by phenolic antioxidants

30 May 2018

1 reference

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17 beta-estradiol hydroxylation catalyzed by human cytochrome P450 1A1: a comparison of the activities induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in MCF-7 cells with those from heterologous expression of the cDNA

30 May 2018

1 reference

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The Cap'n'Collar basic leucine zipper transcription factor Nrf2 (NF-E2 p45-related factor 2) controls both constitutive and inducible expression of intestinal detoxification and glutathione biosynthetic enzymes

30 May 2018

1 reference

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Chemoprevention of aflatoxin B1 hepatocarcinogenesis by coumarin, a natural benzopyrone that is a potent inducer of aflatoxin B1-aldehyde reductase, the glutathione S-transferase A5 and P1 subunits, and NAD(P)H:quinone oxidoreductase in rat liver.

28 November 2018

1 reference

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51 Assays for differentiation of glutathione S-Transferases

28 November 2018

1 reference

12 December 2020

HPLC analysis of linear furocoumarins (psoralens) in healthy celery (Apium graveolens)

1 reference

12 December 2020

Isopimpinellin is not phototoxic in a chick skin assay

1 reference

12 December 2020

Effects of administration of the chemoprotective agent oltipraz on CYP1A and CYP2B in rat liver and rat hepatocytes in culture

1 reference

12 December 2020

Quantification of total furocoumarins in citrus oils by HPLC coupled with UV, fluorescence, and mass detection

1 reference

12 December 2020

A method for quantitative determination of furanocoumarins in capsules and tablets of phytochemical preparations

1 reference

12 December 2020