Suppressor role of activating transcription factor 2 (ATF2) in skin cancer (Q24652406)

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1 January 2020

title

Suppressor role of activating transcription factor 2 (ATF2) in skin cancer (English)

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6

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Zeev Ronai

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author name string

Anindita Bhoumik

1

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1 January 2020

Boris Fichtman

2

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1 January 2020

Charles Derossi

3

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1 January 2020

Wolfgang Breitwieser

4

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1 January 2020

Harriet M Kluger

5

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1 January 2020

Antonio Subtil

7

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1 January 2020

Paul Meltzer

8

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1 January 2020

Stan Krajewski

9

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1 January 2020

Nic Jones

10

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1 January 2020

language of work or name

English

0 references

publication date

28 January 2008

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18227516%20AND%20SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

1 January 2020

published in

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volume

105

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issue

5

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1 January 2020

page(s)

1674-1679

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Notch1 is a p53 target gene involved in human keratinocyte tumor suppression through negative regulation of ROCK1/2 and MRCKalpha kinases

1 January 2020

cites work

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ATM-dependent phosphorylation of ATF2 is required for the DNA damage response

7 April 2017

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Transcriptional switch by activating transcription factor 2-derived peptide sensitizes melanoma cells to apoptosis and inhibits their tumorigenicity

7 April 2017

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Identification of c-MYC as a target of the APC pathway

7 April 2017

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ATF-2 is preferentially activated by stress-activated protein kinases to mediate c-jun induction in response to genotoxic agents

7 April 2017

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Presenilin couples the paired phosphorylation of beta-catenin independent of axin: implications for beta-catenin activation in tumorigenesis

7 April 2017

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Distinct roles of Jun : Fos and Jun : ATF dimers in oncogenesis

7 April 2017

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A presenilin-1-dependent gamma-secretase-like protease mediates release of Notch intracellular domain

7 April 2017

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Transcription factor ATF2 regulation by the JNK signal transduction pathway

7 April 2017

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Presenilin/gamma-secretase-dependent processing of beta-amyloid precursor protein regulates EGF receptor expression

7 April 2017

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Loss of presenilin 1 is associated with enhanced beta-catenin signaling and skin tumorigenesis

7 April 2017

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Notch1 functions as a tumor suppressor in mouse skin

7 April 2017

1 reference

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The cyclin D1 gene is a target of the beta-catenin/LEF-1 pathway

7 April 2017

1 reference

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Presenilin 1 regulates epidermal growth factor receptor turnover and signaling in the endosomal-lysosomal pathway.

7 April 2017

1 reference

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Reduced levels of ATF-2 predispose mice to mammary tumors.

28 September 2017

1 reference

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An ATF2-derived peptide sensitizes melanomas to apoptosis and inhibits their growth and metastasis

28 September 2017

1 reference

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Activating transcription factor 2-derived peptides alter resistance of human tumor cell lines to ultraviolet irradiation and chemical treatment

28 September 2017

1 reference

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Assembly of a functional beta interferon enhanceosome is dependent on ATF-2-c-jun heterodimer orientation

28 September 2017

1 reference

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Transgenic mice demonstrate AP-1 (activator protein-1) transactivation is required for tumor promotion

28 September 2017

1 reference

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Transcription factor ATF2 cooperates with v-Jun to promote growth factor-independent proliferation in vitro and tumor formation in vivo

28 September 2017

1 reference

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Reduced skin tumor development in cyclin D1-deficient mice highlights the oncogenic ras pathway in vivo

28 September 2017

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p300 and ATF-2 are components of the DRF complex, which regulates retinoic acid- and E1A-mediated transcription of the c-jun gene in F9 cells

28 September 2017

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Cell-type-specific regulation of the human tumor necrosis factor alpha gene in B cells and T cells by NFATp and ATF-2/JUN.

28 September 2017

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Transactivation by the human T-cell leukemia virus Tax protein is mediated through enhanced binding of activating transcription factor-2 (ATF-2) ATF-2 response and cAMP element-binding protein (CREB).

28 September 2017

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Blocking of tumor promoter-induced AP-1 activity inhibits induced transformation in JB6 mouse epidermal cells

28 September 2017

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Oncogene activation and tumor suppressor gene inactivation during multistage mouse skin carcinogenesis.

28 September 2017

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The pathogenesis of squamous cell cancer: lessons learned from studies of skin carcinogenesis--thirty-third G. H. A. Clowes Memorial Award Lecture.

28 September 2017

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Heterodimer formation between CREB and JUN proteins.

28 September 2017

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Down-regulation of the cyclin A promoter in differentiating human embryonal carcinoma cells is mediated by depletion of ATF-1 and ATF-2 in the complex at the ATF/CRE site

28 September 2017

1 reference

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Transformation reversion induced in JB6 RT101 cells by AP-1 inhibitors

28 September 2017

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c-Jun regulates eyelid closure and skin tumor development through EGFR signaling

28 September 2017

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Tumour necrosis factor-alpha mediates tumour promotion via a PKC alpha- and AP-1-dependent pathway

30 May 2018

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Suppression of skin tumorigenesis in c-Jun NH(2)-terminal kinase-2-deficient mice.

30 May 2018

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High levels of phosphorylated c-Jun, Fra-1, Fra-2 and ATF-2 proteins correlate with malignant phenotypes in the multistage mouse skin carcinogenesis model.

30 May 2018

1 reference

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Selective DNA bending by a variety of bZIP proteins

30 May 2018

1 reference

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An activated Harvey ras oncogene produces benign tumours on mouse epidermal tissue

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234203

Inhibition of melanoma growth and metastasis by ATF2-derived peptides.

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0706057105

Dominant-negative activator protein 1 (TAM67) targets cyclooxygenase-2 and osteopontin under conditions in which it specifically inhibits tumorigenesis

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1073%2FPNAS.0706057105

Quantitation of early clonal expansion of two mutant 61st codon c-Ha-ras alleles in DMBA/TPA treated mouse skin by nested PCR/RFLP.

21 January 2018

1 reference

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https://api.crossref.org/works/10.1073%2FPNAS.0706057105

Subcellular localization of activating transcription factor 2 in melanoma specimens predicts patient survival.

21 January 2018

1 reference

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Inhibition of tumor promoter-induced transformation by retinoids that transrepress AP-1 without transactivating retinoic acid response element.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234203

Overexpression of cyclin D1 in mouse skin carcinogenesis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2234203

C57BL/6 mice are resistant to tumor promotion by full thickness skin wounding

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18227516

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mouse ATF-2 null mutants display features of a severe type of meconium aspiration syndrome

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18227516

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0706057105

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18227516%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

ADS bibcode

2008PNAS..105.1674B

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18227516%20AND%20SRC:MED&resulttype=core&format=json

1 January 2020

2 references