Identification and absolute configuration of dihydroxy-arachidonic acids formed by oxygenation of 5S-HETE by native and aspirin-acetylated COX-2 (Q24652655)

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scientific article published 2010

Language	Label	Description	Also known as
English	Identification and absolute configuration of dihydroxy-arachidonic acids formed by oxygenation of 5S-HETE by native and aspirin-acetylated COX-2	scientific article published 2010

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scholarly article

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Identification and absolute configuration of dihydroxy-arachidonic acids formed by oxygenation of 5S-HETE by native and aspirin-acetylated COX-2 (English)

0 references

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1 reference

based on heuristic

inferred from title

5(S),15(R)-DiHETE

1 reference

ChEBI release 2020-05-28

5(S),11(R)-DiHETE

1 reference

ChEBI release 2020-05-28

Claus Schneider

6

1 reference

Europe PubMed Central

PubMed publication ID

https://pubmed.ncbi.nlm.nih.gov/19752399/

20 April 2021

2

object named as

Takashi Suzuki

1 reference

Europe PubMed Central

PubMed publication ID

https://pubmed.ncbi.nlm.nih.gov/19752399/

20 April 2021

author name string

Surafel Mulugeta

1

1 reference

Europe PubMed Central

PubMed publication ID

https://pubmed.ncbi.nlm.nih.gov/19752399/

20 April 2021

Noemi Tejera Hernandez

3

1 reference

Europe PubMed Central

PubMed publication ID

https://pubmed.ncbi.nlm.nih.gov/19752399/

20 April 2021

Markus Griesser

4

1 reference

Europe PubMed Central

PubMed publication ID

https://pubmed.ncbi.nlm.nih.gov/19752399/

20 April 2021

William E Boeglin

5

1 reference

Europe PubMed Central

PubMed publication ID

https://pubmed.ncbi.nlm.nih.gov/19752399/

20 April 2021

language of work or name

0 references

publication date

March 2010

1 reference

Europe PubMed Central

PubMed publication ID

https://pubmed.ncbi.nlm.nih.gov/19752399/

20 April 2021

Journal of Lipid Research

1 reference

Europe PubMed Central

PubMed publication ID

https://pubmed.ncbi.nlm.nih.gov/19752399/

20 April 2021

51

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3

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575-85

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Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

7 April 2017

Molecular dynamics simulations of arachidonic acid-derived pentadienyl radical intermediate complexes with COX-1 and COX-2: insights into oxygenation regio- and stereoselectivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

7 April 2017

Lipoxins and aspirin-triggered 15-epi-lipoxin biosynthesis: an update and role in anti-inflammation and pro-resolution

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

7 April 2017

Structural characterization of arachidonyl radicals formed by aspirin-treated prostaglandin H synthase-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

7 April 2017

Control of prostaglandin stereochemistry at the 15-carbon by cyclooxygenases-1 and -2. A critical role for serine 530 and valine 349

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

7 April 2017

Analysis of hydroperoxide-induced tyrosyl radicals and lipoxygenase activity in aspirin-treated human prostaglandin H synthase-2

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

7 April 2017

On the mechanism of the biosynthesis of prostaglandins E-1 and F-1-alpha

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

7 April 2017

Acetylation of human prostaglandin endoperoxide synthase-2 (cyclooxygenase-2) by aspirin

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

7 April 2017

Single protein from human leukocytes possesses 5-lipoxygenase and leukotriene A4 synthase activities

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

7 April 2017

Convergence of the 5-LOX and COX-2 pathways: heme-catalyzed cleavage of the 5S-HETE-derived di-endoperoxide into aldehyde fragments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

28 September 2017

Acetylation of prostaglandin H2 synthases by aspirin is inhibited by redox cycling of the peroxidase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

28 September 2017

Cyclooxygenase-2-mediated metabolism of arachidonic acid to 15-oxo-eicosatetraenoic acid by rat intestinal epithelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

28 September 2017

Control of oxygenation in lipoxygenase and cyclooxygenase catalysis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

28 September 2017

Inflammatory resolution: new opportunities for drug discovery

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

28 September 2017

Different catalytically competent arrangements of arachidonic acid within the cyclooxygenase active site of prostaglandin endoperoxide H synthase-1 lead to the formation of different oxygenated products

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

28 September 2017

Spatial requirements for 15-(R)-hydroxy-5Z,8Z,11Z, 13E-eicosatetraenoic acid synthesis within the cyclooxygenase active site of murine COX-2. Why acetylated COX-1 does not synthesize 15-(R)-hete

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

28 September 2017

Formation of a novel dihydroxy acid from arachidonic acid by lipoxygenase-catalyzed double oxygenation in rat mononuclear cells and human leukocytes.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

28 September 2017

15-Hydroxy-5,8,11,13-eicosatetraenoic acid inhibits human vascular cyclooxygenase. Potential role in diabetic vascular disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

28 September 2017

The aspirin and heme-binding sites of ovine and murine prostaglandin endoperoxide synthases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

28 September 2017

Identification of 5-oxo-15-hydroxy-6,8,11,13-eicosatetraenoic acid as a novel and potent human eosinophil chemotactic eicosanoid

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

28 September 2017

Leukotriene C: a slow-reacting substance from murine mastocytoma cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

28 September 2017

Double dioxygenation of arachidonic acid by soybean lipoxygenase-1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

28 September 2017

Mutation of serine-516 in human prostaglandin G/H synthase-2 to methionine or aspirin acetylation of this residue stimulates 15-R-HETE synthesis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

28 September 2017

Convergent oxygenation of arachidonic acid by 5-lipoxygenase and cyclooxygenase-2.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

30 May 2018

Enantiomeric separation of hydroxy eicosanoids by chiral column chromatography: effect of the alcohol modifier.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

30 May 2018

Effect of 15-lipoxygenase-derived arachidonate metabolites on human neutrophil degranulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

30 May 2018

Formation of 11-hydroxyeicosatetraenoic acid and 15-hydroxyeicosatetraenoic acid in human umbilical arteries is catalyzed by cyclooxygenase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

30 May 2018

Eggs of the sea urchin, Strongylocentrotus purpuratus, contain a prominent (11R) and (12R) lipoxygenase activity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

30 May 2018

Stereospecificity of the hydroxyeicosatetraenoic and hydroxyoctadecadienoic acids produced by cultured bovine endothelial cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2817587

30 May 2018

A 49-kDa mini-lipoxygenase from Anabaena sp. PCC 7120 retains catalytically complete functionality

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M001719

21 January 2018

Identification of the peroxidation products of 13-hydroxy-gamma-linolenate and 15-hydroxyarachidonate: mechanistic studies on the formation of leukotriene-like diols

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M001719

21 January 2018

Identification of Two Cyclooxygenase Active Site Residues, Leucine 384 and Glycine 526, That Control Carbon Ring Cyclization in Prostaglandin Biosynthesis

1 reference

https://api.crossref.org/works/10.1194%2FJLR.M001719

21 January 2018

Stereospecificity of hydrogen abstraction in the conversion of arachidonic acid to 15R-HETE by aspirin-treated cyclooxygenase-2. Implications for the alignment of substrate in the active site

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Oxygenation of Unsaturated Fatty Acids by the Vesicular Gland of Sheep

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A test for the intermediacy of 11-hydroperoxyeicosa-5,8,12,14-tetraenoic acid [11-HPETE] in prostaglandin biosynthesis

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Double dioxygenation of arachidonic acid by soybean lipoxygenase-1. Kinetics and regio-stereo specificities of the reaction steps

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a novel and highly potent eosinophil chemotactic lipid in human eosinophils treated with arachidonic acid

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identification of a pharmacologically distinct prostaglandin H synthase in cultured epithelial cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection, assay, and isolation of allene oxide synthase

1 reference

https://pubmed.ncbi.nlm.nih.gov/19752399

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.1194/JLR.M001719

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PubMed publication ID

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