Inflammatory resolution: new opportunities for drug discovery (Q35770168)

10 August 2017

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title

Inflammatory resolution: new opportunities for drug discovery (English)

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10 August 2017

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Derek W Gilroy

1

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Mauro Perretti

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3

object named as

Mauro Perretti

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10 August 2017

Toby Lawrence

2

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PubMed ID

15136788

10 August 2017

Adriano G Rossi

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4

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10 August 2017

1 May 2004

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Nature Reviews Drug Discovery

10 August 2017

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10 August 2017

3

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10 August 2017

5

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10 August 2017

401-416

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https://scigraph.springernature.com/pub.10.1038/nrd1383

10 August 2017

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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The NF-kappa B cascade is important in Bcl-xL expression and for the anti-apoptotic effects of the CD28 receptor in primary human CD4+ lymphocytes

31 March 2020

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NF-κB Activation Is a Critical Regulator of Human Granulocyte Apoptosisin Vitro

31 March 2020

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Possible new role for NF-kappaB in the resolution of inflammation.

31 March 2020

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31 March 2020

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Regulation of an essential innate immune response by the p50 subunit of NF-kappaB.

31 March 2020

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The two faces of IKK and NF-κB inhibition: prevention of systemic inflammation but increased local injury following intestinal ischemia-reperfusion

31 March 2020

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31 March 2020

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31 March 2020

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The effect of adrenalectomy on interleukin-1 release in vitro and in vivo

31 March 2020

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Molecular mechanisms of glucocorticosteroid actions.

31 March 2020

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Immunosuppression by glucocorticoids: inhibition of NF-kappa B activity through induction of I kappa B synthesis

31 March 2020

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Bioenergetics of immune functions: fundamental and therapeutic aspects

31 March 2020

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The glucocorticoid receptor inhibits NFkappaB by interfering with serine-2 phosphorylation of the RNA polymerase II carboxy-terminal domain

31 March 2020

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31 March 2020

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Lipocortin 1 mediates dexamethasone-induced growth arrest of the A549 lung adenocarcinoma cell line

31 March 2020

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Macrophage-specific eicosanoid synthesis inhibition and lipocortin-1 induction by glucocorticoids

31 March 2020

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Annexins: from structure to function

31 March 2020

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Endogenous lipid- and peptide-derived anti-inflammatory pathways generated with glucocorticoid and aspirin treatment activate the lipoxin A4 receptor

31 March 2020

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Formyl-peptide receptors revisited

31 March 2020

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31 March 2020

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31 March 2020

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Modulation of inflammation and response to dexamethasone by Annexin 1 in antigen-induced arthritis.

31 March 2020

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The annexin 1 receptor(s): is the plot unravelling?

31 March 2020

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Adenosine: an endogenous regulator of innate immunity

31 March 2020

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Use of the A(2A) adenosine receptor as a physiological immunosuppressor and to engineer inflammation in vivo

31 March 2020

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Methotrexate inhibits neutrophil function by stimulating adenosine release from connective tissue cells

31 March 2020

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The antiinflammatory mechanism of methotrexate. Increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vivo model of inflammation.

31 March 2020

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Adenosine A2A or A3 receptors are required for inhibition of inflammation by methotrexate and its analog MX-68.

31 March 2020

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Adenosine: a potential mediator of immunosuppression in multiple organ failure

31 March 2020

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Too much of a good thing: adenosine overload in adenosine-deaminase-deficient mice

31 March 2020

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Targeting melanocortin receptors as a novel strategy to control inflammation.

31 March 2020

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The role of phosphatidylserine in recognition of apoptotic cells by phagocytes

31 March 2020

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Annexin I Is an Endogenous Ligand that Mediates Apoptotic Cell Engulfment

31 March 2020

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Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-beta1 secretion and the resolution of inflammation

31 March 2020

1 reference

Transcellular conversion of endogenous arachidonic acid to lipoxins in mixed human platelet-granulocyte suspensions

31 March 2020

1 reference

Formation of lipoxins and leukotrienes during receptor-mediated interactions of human platelets and recombinant human granulocyte/macrophage colony-stimulating factor-primed neutrophils

31 March 2020

1 reference

Lipoxins: novel series of biologically active compounds formed from arachidonic acid in human leukocytes

31 March 2020

1 reference

Aspirin triggers previously undescribed bioactive eicosanoids by human endothelial cell-leukocyte interactions

31 March 2020

1 reference

Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation

31 March 2020

1 reference

IL-6 and Its Soluble Receptor Orchestrate a Temporal Switch in the Pattern of Leukocyte Recruitment Seen during Acute Inflammation

31 March 2020

1 reference

Anti-inflammatory cyclopentenone prostaglandins are direct inhibitors of IkappaB kinase

31 March 2020

1 reference

Inhibition of IkappaB kinase and IkappaB phosphorylation by 15-deoxy-Delta(12,14)-prostaglandin J(2) in activated murine macrophages

31 March 2020

1 reference

15-Deoxy-Delta 12,14-prostaglandin J2 inhibition of NF-kappaB-DNA binding through covalent modification of the p50 subunit

31 March 2020

1 reference

Biosynthesis of 15-deoxy-delta12,14-PGJ2 and the ligation of PPARgamma

31 March 2020

1 reference

Aspirin-triggered 15-epi-lipoxin A4 and novel lipoxin B4 stable analogs inhibit neutrophil-mediated changes in vascular permeability.

31 March 2020

1 reference

inferred from DOI database lookup

7 January 2021

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Identifiers

DOI

10.1038/NRD1383

1 reference

10 August 2017

1 reference

PubMed ID

15136788