beta-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice (Q24654027)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19349687%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

title

beta-Arrestin1 mediates nicotinic acid-induced flushing, but not its antilipolytic effect, in mice (English)

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25 January 2020

2

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25 January 2020

Scott M DeWire

5

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25 January 2020

10

Robert J Lefkowitz

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25 January 2020

author name string

Robert W Walters

1

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25 January 2020

Jeffrey J Kovacs

3

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25 January 2020

Jonathan D Violin

4

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25 January 2020

Christopher M Lam

6

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25 January 2020

J Ruthie Chen

7

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25 January 2020

Michael J Muehlbauer

8

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25 January 2020

Erin J Whalen

9

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25 January 2020

language of work or name

English

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publication date

6 April 2009

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25 January 2020

number of pages

10

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Journal of Clinical Investigation

inferred from page(s)

published in

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25 January 2020

volume

119

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25 January 2020

issue

5

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25 January 2020

page(s)

1312-1321

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Functional specialization of beta-arrestin interactions revealed by proteomic analysis

25 January 2020

cites work

1 reference

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GPR109A (PUMA-G/HM74A) mediates nicotinic acid-induced flushing

7 April 2017

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Flushing out the role of GPR109A (HM74A) in the clinical efficacy of nicotinic acid

7 April 2017

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Tamoxifen stimulates arachidonic acid release from rat liver cells by an estrogen receptor-independent, non-genomic mechanism

7 April 2017

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Desensitization, internalization, and signaling functions of beta-arrestins demonstrated by RNA interference

7 April 2017

1 reference

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beta-arrestin differentially regulates the chemokine receptor CXCR4-mediated signaling and receptor internalization, and this implicates multiple interaction sites between beta-arrestin and CXCR4

7 April 2017

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cPLA2 is phosphorylated and activated by MAP kinase

7 April 2017

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Nicotinic acid receptor agonists differentially activate downstream effectors

7 April 2017

1 reference

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Suppression of niacin-induced vasodilation with an antagonist to prostaglandin D2 receptor subtype 1

7 April 2017

1 reference

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Nicotinic acid induces secretion of prostaglandin D2 in human macrophages: an in vitro model of the niacin flush

7 April 2017

1 reference

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Transduction of receptor signals by beta-arrestins

7 April 2017

1 reference

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PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect

7 April 2017

1 reference

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Molecular identification of high and low affinity receptors for nicotinic acid

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673863

Enhanced morphine analgesia in mice lacking beta-arrestin 2

7 April 2017

2 references

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7 April 2017

https://api.crossref.org/works/10.1172%2FJCI36806

7 January 2021

inferred from DOI database lookup

Clathrin-mediated endocytosis of the beta-adrenergic receptor is regulated by phosphorylation/dephosphorylation of beta-arrestin1

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673863

Beta-arrestin2, a novel member of the arrestin/beta-arrestin gene family

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673863

Identification of skin as a major site of prostaglandin D2 release following oral administration of niacin in humans

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673863

Mu-opioid receptor desensitization by beta-arrestin-2 determines morphine tolerance but not dependence

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673863

Beta-arrestins and cell signaling

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673863

beta-arrestin-biased agonism at the beta2-adrenergic receptor

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673863

beta2-adrenergic receptor signaling and desensitization elucidated by quantitative modeling of real time cAMP dynamics

28 September 2017

1 reference

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A unique mechanism of beta-blocker action: carvedilol stimulates beta-arrestin signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673863

Functional selectivity through protean and biased agonism: who steers the ship?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673863

Niacin in cardiovascular prevention: mechanisms, efficacy, and safety.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673863

New roles for beta-arrestins in cell signaling: not just for seven-transmembrane receptors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673863

Nicotinic acid-induced flushing is mediated by activation of epidermal langerhans cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673863

G-protein-coupled receptor kinase specificity for beta-arrestin recruitment to the beta2-adrenergic receptor revealed by fluorescence resonance energy transfer

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673863

Distinct beta-arrestin- and G protein-dependent pathways for parathyroid hormone receptor-stimulated ERK1/2 activation.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673863

Monitoring agonist-promoted conformational changes of beta-arrestin in living cells by intramolecular BRET.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673863

Fluorescent indicators of cAMP and Epac activation reveal differential dynamics of cAMP signaling within discrete subcellular compartments

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673863

Differential desensitization, receptor phosphorylation, beta-arrestin recruitment, and ERK1/2 activation by the two endogenous ligands for the CC chemokine receptor 7.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673863

Independent beta-arrestin 2 and G protein-mediated pathways for angiotensin II activation of extracellular signal-regulated kinases 1 and 2.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673863

Niacin and cholesterol: role in cardiovascular disease (review).

28 September 2017

1 reference

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Fifteen year mortality in Coronary Drug Project patients: long-term benefit with niacin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673863

Prostaglandins contribute to the vasodilation induced by nicotinic acid

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673863

Studies on the Mechanism of Flush Induced by Nicotinic Acid

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673863

Effects of a niacin receptor partial agonist, MK-0354, on plasma free fatty acids, lipids, and cutaneous flushing in humans

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673863

Differential mechanisms of morphine antinociceptive tolerance revealed in (beta)arrestin-2 knock-out mice.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2673863

3-(1H-tetrazol-5-yl)-1,4,5,6-tetrahydro-cyclopentapyrazole (MK-0354): a partial agonist of the nicotinic acid receptor, G-protein coupled receptor 109a, with antilipolytic but no vasodilatory activity in mice.

30 May 2018

1 reference

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The Study of the Effects of Diet on Metabolism and Nutrition (STEDMAN) weight loss project: Rationale and design

28 November 2018

1 reference

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Morphine side effects in beta-arrestin 2 knockout mice

28 November 2018

1 reference

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Niacin, but not gemfibrozil, selectively increases LP-AI, a cardioprotective subfraction of HDL, in patients with low HDL cholesterol

28 November 2018

1 reference

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Cytosolic phospholipase A(2) activity associated with nuclei is not inhibited by arachidonyl trifluoromethyl ketone in macrophages stimulated with receptor-recognized forms of alpha(2)-macroglobulin

28 November 2018

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12 December 2020

Islet‐activating protein discriminates the antilipolytic mechanism of insulin from that of other antilipolytic compounds

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12 December 2020

Niacin accelerates intracellular ApoB degradation by inhibiting triacylglycerol synthesis in human hepatoblastoma (HepG2) cells

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12 December 2020

Niacin decreases removal of high-density lipoprotein apolipoprotein A-I but not cholesterol ester by Hep G2 cells. Implication for reverse cholesterol transport

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12 December 2020

Regulation of cytosolic phospholipase A2 activity in macrophages stimulated with receptor-recognized forms of alpha 2-macroglobulin: role in mitogenesis and cell proliferation

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12 December 2020

The role of receptor kinases and arrestins in G protein-coupled receptor regulation

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12 December 2020

Identifiers

DOI

10.1172/JCI36806

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19349687%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19349687%20AND%20SRC:MED&resulttype=core&format=json

25 January 2020

2 references