A systems approach to prion disease (Q24656032)

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24 January 2020

title

A systems approach to prion disease (English)

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24 January 2020

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4

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24 January 2020

Nathan D Price

11

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24 January 2020

author name string

Daehee Hwang

1

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24 January 2020

Inyoul Y Lee

2

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24 January 2020

Hyuntae Yoo

3

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24 January 2020

Ji-Hoon Cho

5

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24 January 2020

Brianne Petritis

6

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24 January 2020

David Baxter

7

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24 January 2020

Rose Pitstick

8

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24 January 2020

Rebecca Young

9

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24 January 2020

Doug Spicer

10

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24 January 2020

John G Hohmann

12

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24 January 2020

Stephen J Dearmond

13

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24 January 2020

George A Carlson

14

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24 January 2020

Leroy E Hood

15

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24 January 2020

language of work or name

English

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publication date

24 March 2009

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Molecular Systems Biology

24 January 2020

published in

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24 January 2020

volume

5

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24 January 2020

page(s)

252

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Intracellular cholesterol transporter StarD4 binds free cholesterol and increases cholesteryl ester formation

24 January 2020

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7 April 2017

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Eight prion strains have PrP(Sc) molecules with different conformations

7 April 2017

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Genetic heterogeneity versus molecular analysis of prion susceptibility in neuroblasma N2a sublines

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CMTM3 can affect the transcription activity of androgen receptor and inhibit the expression level of PSA in LNCaP cells

28 September 2017

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Comprehensive transcriptional profiling of prion infection in mouse models reveals networks of responsive genes

28 September 2017

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The CNS glycoprotein Shadoo has PrP(C)-like protective properties and displays reduced levels in prion infections

28 September 2017

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Modulation of proteinase K-resistant prion protein in cells and infectious brain homogenate by redox iron: implications for prion replication and disease pathogenesis

28 September 2017

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Lethal recessive myelin toxicity of prion protein lacking its central domain

28 September 2017

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Molecular mechanisms mediating pathological plasticity in Huntington's disease and Alzheimer's disease

28 September 2017

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Ultrastructural alterations in the optic nerve in transmissible spongiform encephalopathies or prion diseases--a review.

28 September 2017

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Tricyclic antidepressants, quinacrine and a novel, synthetic chimera thereof clear prions by destabilizing detergent-resistant membrane compartments

28 September 2017

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Gene expression alterations in brains of mice infected with three strains of scrapie

28 September 2017

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Prion infection of mouse neurospheres

28 September 2017

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Microglial cells in neurodegenerative disorders.

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Heparan sulfate is a cellular receptor for purified infectious prions.

28 September 2017

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Notch-1 activation and dendritic atrophy in prion disease

28 September 2017

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Systems biology and new technologies enable predictive and preventative medicine.

28 September 2017

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Identification of differentially expressed genes in scrapie-infected mouse brains by using global gene expression technology

28 September 2017

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Diagnosing prion diseases: needs, challenges and hopes

28 September 2017

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Neuronal cell death in transmissible spongiform encephalopathies (prion diseases) revisited: from apoptosis to autophagy.

28 September 2017

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28 September 2017

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28 September 2017

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Detection of new quantitative trait Loci for susceptibility to transmissible spongiform encephalopathies in mice

28 September 2017

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28 September 2017

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28 September 2017

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Regulating factors for microglial activation

28 September 2017

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Atypical inflammation in the central nervous system in prion disease

28 September 2017

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Microglia and prion disease

28 September 2017

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28 September 2017

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Identification of multiple quantitative trait loci linked to prion disease incubation period in mice

28 September 2017

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Selective neuronal vulnerability in human prion diseases. Fatal familial insomnia differs from other types of prion diseases

28 September 2017

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Prion rods contain small amounts of two host sphingolipids as revealed by thin-layer chromatography and mass spectrometry

28 September 2017

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Evidence for protein X binding to a discontinuous epitope on the cellular prion protein during scrapie prion propagation

28 September 2017

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Subcellular colocalization of the cellular and scrapie prion proteins in caveolae-like membranous domains

28 September 2017

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Decreased receptor-mediated calcium response in prion-infected cells correlates with decreased membrane fluidity and IP3 release

28 September 2017

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Relationship of iron to oligodendrocytes and myelination

28 September 2017

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Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice

28 September 2017

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Prions--infectious pathogens causing the spongiform encephalopathies.

28 September 2017

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Selective neuronal vulnerability during experimental scrapie infection: insights from an ultrastructural investigation

28 September 2017

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High prion and PrPSc levels but delayed onset of disease in scrapie-inoculated mice heterozygous for a disrupted PrP gene

30 May 2018

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Delimiting the location of the scrapie prion incubation time gene on chromosome 2 of the mouse

30 May 2018

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Scrapie prions alter receptor-mediated calcium responses in cultured cells

30 May 2018

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Microglial and astroglial reactions to anterograde axonal degeneration: a histochemical and immunocytochemical study of the adult rat fascia dentata after entorhinal perforant path lesions

30 May 2018

1 reference

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PrP gene dosage determines the timing but not the final intensity or distribution of lesions in scrapie pathology

30 May 2018

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Identification of scrapie prion protein-specific mRNA in scrapie-infected and uninfected brain

30 May 2018

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Distinct prion proteins in short and long scrapie incubation period mice

30 May 2018

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Cellular heparan sulfate participates in the metabolism of prions

30 May 2018

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The neurodegeneration sequence in prion diseases: evidence from functional, morphological and ultrastructural studies of the GABAergic system

21 January 2018

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Gene expression profiling of the preclinical scrapie-infected hippocampus

21 January 2018

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PrP in pathology and pathogenesis in scrapie-infected mice

21 January 2018

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Gene expression in scrapie. Cloning of a new scrapie-responsive gene and the identification of increased levels of seven other mRNA transcripts

21 January 2018

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Copaxone interferes with the PrP Sc-GAG interaction.

21 January 2018

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PrPSc incorporation to cells requires endogenous glycosaminoglycan expression

21 January 2018

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Expression and catalytic activity of mouse leukotriene B4 omega-hydroxylase, CYP4F14.

21 January 2018

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Complement facilitates early prion pathogenesis

21 January 2018

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Chemically induced accumulation of GAGs delays PrP(Sc) clearance but prolongs prion disease incubation time

21 January 2018

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The metabolism of glycosaminoglycans is impaired in prion diseases

21 January 2018

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Effect of manipulation of iron storage, transport, or availability on myelin composition and brain iron content in three different animal models.

21 January 2018

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Early and rapid engraftment of bone marrow-derived microglia in scrapie.

21 January 2018

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Gene expression profiling of scrapie-infected brain tissue.

21 January 2018

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Presymptomatic detection of prions in blood.

21 January 2018

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Prion clearance in bigenic mice

21 January 2018

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Pre-symptomatic detection of prions by cyclic amplification of protein misfolding.

21 January 2018

1 reference

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P2Y nucleotide receptor interaction with alpha integrin mediates astrocyte migration

21 January 2018

1 reference

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PrP deposition, microglial activation, and neuronal apoptosis in murine scrapie

21 January 2018

1 reference

https://api.crossref.org/works/10.1038%2FMSB.2009.10

Transcriptome analysis reveals altered cholesterol metabolism during the neurodegeneration in mouse scrapie model

21 January 2018

1 reference

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Up-regulation of cathepsin B and cathepsin L activities in scrapie-infected mouse Neuro2a cells

21 January 2018

1 reference

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Severe, early and selective loss of a subpopulation of GABAergic inhibitory neurons in experimental transmissible spongiform encephalopathies

21 January 2018

1 reference

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Role of microglia in neuronal cell death in prion disease

28 November 2018

1 reference

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Distribution of parvalbumin-immunoreactive neurons in brain correlates with hippocampal and temporal cortical pathology in Creutzfeldt-Jakob disease

28 November 2018

1 reference

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Synapse loss associated with abnormal PrP precedes neuronal degeneration in the scrapie-infected murine hippocampus

28 November 2018

1 reference

12 December 2020

Quantitative trait loci affecting prion incubation time in mice

1 reference

12 December 2020

Increased ferric iron content and iron-induced oxidative stress in the brains of scrapie-infected mice

1 reference

12 December 2020

Microglia and the pathogenesis of spongiform encephalopathies

1 reference

12 December 2020

Identification of central nervous system genes involved in the host response to the scrapie agent during preclinical and clinical infection

1 reference

12 December 2020

Heparin-like molecules bind differentially to prion-proteins and change their intracellular metabolic fate

1 reference

12 December 2020

Glial responses to hypoxic/ischemic encephalopathy in neonatal rat cerebrum

1 reference

12 December 2020

C1q binding and complement activation by prions and amyloids

1 reference

12 December 2020

JAK-STAT signaling pathway mediates astrogliosis in brains of scrapie-infected mice

1 reference

12 December 2020

Identifiers

DOI

10.1038/MSB.2009.10

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19308092%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19308092%20AND%20SRC:MED&resulttype=core&format=json

24 January 2020

PubMed publication ID

19308092

2 references