CD4+ FoxP3+ regulatory T cells confer infectious tolerance in a TGF-beta-dependent manner (Q24656647)

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Dat Q Tran

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Marko Pesu

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Todd S Davidson

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Heather Ramsey

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John J O'Shea

Journal of Experimental Medicine

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language of work or name

English

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publication date

1 September 2008

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published in

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volume

205

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issue

9

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page(s)

1975-81

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cites work

T-cell-expressed proprotein convertase furin is essential for maintenance of peripheral immune tolerance

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Conversion of peripheral CD4+CD25- naive T cells to CD4+CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3

7 April 2017

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Disruption of a new forkhead/winged-helix protein, scurfin, results in the fatal lymphoproliferative disorder of the scurfy mouse

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Foxp3 programs the development and function of CD4+CD25+ regulatory T cells

7 April 2017

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Control of regulatory T cell development by the transcription factor Foxp3

7 April 2017

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T cell-produced transforming growth factor-beta1 controls T cell tolerance and regulates Th1- and Th17-cell differentiation

7 April 2017

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The lifestyle of naturally occurring CD4+ CD25+ Foxp3+ regulatory T cells

7 April 2017

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An essential role for Scurfin in CD4+CD25+ T regulatory cells

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The immune dysregulation, polyendocrinopathy, enteropathy, X-linked syndrome (IPEX) is caused by mutations of FOXP3

7 April 2017

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The Foxp3+ regulatory T cell: a jack of all trades, master of regulation

7 April 2017

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Loss of integrin alpha(v)beta8 on dendritic cells causes autoimmunity and colitis in mice

28 September 2017

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Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype

28 September 2017

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Cutting Edge: IL-2 is essential for TGF-beta-mediated induction of Foxp3+ T regulatory cells

28 September 2017

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Activation-induced FOXP3 in human T effector cells does not suppress proliferation or cytokine production

28 September 2017

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TGF-beta-mediated suppression by CD4+CD25+ T cells is facilitated by CTLA-4 signaling

28 September 2017

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T cells that cannot respond to TGF-beta escape control by CD4(+)CD25(+) regulatory T cells

28 September 2017

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CD4(+)CD25(+) regulatory T cells can mediate suppressor function in the absence of transforming growth factor beta1 production and responsiveness

28 September 2017

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Cell contact-dependent immunosuppression by CD4(+)CD25(+) regulatory T cells is mediated by cell surface-bound transforming growth factor beta

28 September 2017

1 reference

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"Infectious" transplantation tolerance.

28 September 2017

1 reference

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Infectious tolerance: human CD25(+) regulatory T cells convey suppressor activity to conventional CD4(+) T helper cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526184

Human CD4(+)CD25(+) regulatory, contact-dependent T cells induce interleukin 10-producing, contact-independent type 1-like regulatory T cells [corrected].

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526184

Infectious immunological tolerance

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526184

Induction of foxP3+ regulatory T cells in the periphery of T cell receptor transgenic mice tolerized to transplants

30 May 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080308

TGF-beta 1 plays an important role in the mechanism of CD4+CD25+ regulatory T cell activity in both humans and mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080308

TGF-beta1 production by CD4+ CD25+ regulatory T cells is not essential for suppression of intestinal inflammation.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080308

Transient expression of FOXP3 in human activated nonregulatory CD4+ T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20080308

Expression of FOXP3 mRNA is not confined to CD4+CD25+ T regulatory cells in humans.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2526184

CD4+ CD25+ [corrected] regulatory T cells render naive CD4+ CD25- T cells anergic and suppressive

28 November 2018

1 reference

12 December 2020

CD4+CD25+ regulatory T cells are activated in vivo by recognition of self

1 reference

12 December 2020

Cutting edge: regulatory T cells induce CD4+CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta

1 reference

12 December 2020

Autoantigen-specific TGFbeta-induced Foxp3+ regulatory T cells prevent autoimmunity by inhibiting dendritic cells from activating autoreactive T cells

1 reference

12 December 2020

Identifiers

DOI

10.1084/JEM.20080308

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PubMed publication ID

18710931

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