Neuropathic pain activates the endogenous kappa opioid system in mouse spinal cord and induces opioid receptor tolerance (Q24657309)

5

Marc G Caron

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Traci A Czyzyk

7

Traci A Czyzyk

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Jay P McLaughlin

3

Jay P McLaughlin

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Gregory W Terman

9

Gregory W Terman

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author name string

Mei Xu

1

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Michael Petraschka

2

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Ruth E Westenbroek

4

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John E Pintar

8

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Charles Chavkin

Antagonists of the kappa-opioid receptor enhance allodynia in rats and mice after sciatic nerve ligation

10

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language of work or name

English

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publication date

12 May 2004

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published in

Journal of Neuroscience

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volume

24

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page(s)

4576-84

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issue

19

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cites work

1 reference

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Phosphorylation of a carboxyl-terminal serine within the kappa-opioid receptor produces desensitization and internalization

7 April 2017

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7 April 2017

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Prolonged kappa opioid receptor phosphorylation mediated by G-protein receptor kinase underlies sustained analgesic tolerance

28 September 2017

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Induction of pain facilitation by sustained opioid exposure: relationship to opioid antinociceptive tolerance

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Opioids in chronic pain

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Pathobiology of neuropathic pain

28 September 2017

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Mechanisms of opioid-induced pain and antinociceptive tolerance: descending facilitation and spinal dynorphin

28 September 2017

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28 September 2017

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Spinal and supraspinal mechanisms of neuropathic pain

28 September 2017

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Cellular mechanisms of neuropathic pain, morphine tolerance, and their interactions

28 September 2017

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The kappa-opioid receptor is primarily postsynaptic: combined immunohistochemical localization of the receptor and endogenous opioids

28 September 2017

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A peripheral mononeuropathy in rat that produces disorders of pain sensation like those seen in man.

28 September 2017

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Light microscope study of the coexistence of GABA-like and glycine-like immunoreactivities in the spinal cord of the rat.

28 September 2017

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A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury.

28 September 2017

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28 September 2017

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Regional, developmental, and cell cycle-dependent differences in mu, delta, and kappa-opioid receptor expression among cultured mouse astrocytes

28 September 2017

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Agonist-induced phosphorylation of the kappa-opioid receptor

30 May 2018

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Spinal release of immunoreactive dynorphin A(1-8) with the development of peripheral inflammation in the rat.

30 May 2018

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Peripheral kappa 1-opioid receptor-mediated analgesia in mice

30 May 2018

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Dynorphin opioids present in dentate granule cells may function as retrograde inhibitory neurotransmitters.

30 May 2018

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Evidence for a kappa-opioid receptor on pituitary astrocytes: an autoradiographic study

30 May 2018

1 reference

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A novel interaction between dynorphin(1-13) and an N-methyl-D-aspartate site

30 May 2018

1 reference

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Lack of analgesic effect of opioids on neuropathic and idiopathic forms of pain.

30 May 2018

1 reference

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Spinal kappa receptor-mediated analgesia of E-2078, a systemically active dynorphin analog, in mice

30 May 2018

1 reference

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Opioid peptides modulate the response of neurons of the superficial laminae of the rat spinal dorsal horn to GABA.

30 May 2018

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p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain.

28 November 2018

1 reference

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Partial sciatic nerve ligation induces increase in the phosphorylation of extracellular signal-regulated kinase (ERK) and c-Jun N-terminal kinase (JNK) in astrocytes in the lumbar spinal dorsal horn and the gracile nucleus.

28 November 2018

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Time-dependent descending facilitation from the rostral ventromedial medulla maintains, but does not initiate, neuropathic pain.

28 November 2018

1 reference

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Dorsal horn synaptosomal content of aspartate, glutamate, glycine and GABA are differentially altered following chronic constriction injury to the rat sciatic nerve

28 November 2018

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Generation of dynorphin knockout mice.

28 November 2018

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Improgan, a cimetidine analog, induces morphine-like antinociception in opioid receptor-knockout mice

28 November 2018

1 reference

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Dynorphin promotes abnormal pain and spinal opioid antinociceptive tolerance.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376823

Extraterritorial neuropathic pain correlates with multisegmental elevation of spinal dynorphin in nerve-injured rats.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376823

Reorganization of the spinal dorsal horn in models of chronic pain: correlation with behaviour.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376823

G protein-coupled receptor kinase 3 (GRK3) gene disruption leads to loss of odorant receptor desensitization.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376823

Spinally administered dynorphin A produces long-lasting allodynia: involvement of NMDA but not opioid receptors

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376823

The contribution of GABAA and glycine receptors to central sensitization: disinhibition and touch-evoked allodynia in the spinal cord.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376823

kappa-opioid receptor agonists modulate excitatory transmission in substantia gelatinosa neurons of the rat spinal cord

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376823

Nonopiate effects of dynorphin and des-Tyr-dynorphin.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2376823

Effects of traumatic injury on dynorphin immunoreactivity in spinal cord

28 November 2018

1 reference

12 December 2020

Behavioral and autonomic correlates of the tactile evoked allodynia produced by spinal glycine inhibition: effects of modulatory receptor systems and excitatory amino acid antagonists

1 reference

12 December 2020

Extremely long-lasting antagonistic actions of nor-binaltorphimine (nor-BNI) in the mouse tail-flick test

1 reference

12 December 2020

Spinal dynorphin immunoreactivity increases bilaterally in a neuropathic pain model

1 reference

12 December 2020

Reversal of behavioural and electrophysiological correlates of experimental peripheral neuropathy by the NK1 receptor antagonist GR205171 in rats

1 reference

12 December 2020

Pronociceptive actions of dynorphin maintain chronic neuropathic pain

1 reference

12 December 2020

10.1523/JNEUROSCI.5552-03.2004

Identifiers

DOI

1 reference

3625575

3625575

1 reference

1 reference

1 reference