MEP1A allele for meprin A metalloprotease is a susceptibility gene for inflammatory bowel disease (Q24657607)

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22 January 2020

title

MEP1A allele for meprin A metalloprotease is a susceptibility gene for inflammatory bowel disease (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19262505%20AND%20SRC:MED&resulttype=core&format=json

inflammatory bowel diseases

22 January 2020

main subject

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0 references

5

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22 January 2020

author name string

S Banerjee

1

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22 January 2020

B Oneda

2

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22 January 2020

L M Yap

3

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22 January 2020

D P Jewell

4

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22 January 2020

L R Fitzpatrick

6

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22 January 2020

F Seibold

7

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22 January 2020

E E Sterchi

8

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22 January 2020

T Ahmad

9

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22 January 2020

D Lottaz

10

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22 January 2020

J S Bond

11

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22 January 2020

language of work or name

English

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publication date

4 March 2009

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22 January 2020

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22 January 2020

volume

2

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22 January 2020

issue

3

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22 January 2020

page(s)

220-231

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Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease

22 January 2020

cites work

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A second generation human haplotype map of over 3.1 million SNPs

7 April 2017

1 reference

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Targeted disruption of the meprin beta gene in mice leads to underrepresentation of knockout mice and changes in renal gene expression profiles

7 April 2017

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A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease

7 April 2017

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The metzincins — Topological and sequential relations between the astacins, adamalysins, serralysins, and matrixins (collagenases) define a super family of zinc‐peptidases

7 April 2017

1 reference

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A genome-wide association study identifies IL23R as an inflammatory bowel disease gene

7 April 2017

1 reference

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Generation of biologically active interleukin-1beta by meprin B

7 April 2017

1 reference

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Marked differences between metalloproteases meprin A and B in substrate and peptide bond specificity

7 April 2017

1 reference

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Secretion of human meprin from intestinal epithelial cells depends on differential expression of the alpha and beta subunits

7 April 2017

1 reference

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Expression and distribution of meprin protease subunits in mouse intestine

7 April 2017

1 reference

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The structural genes, MEP1A and MEP1B, for the alpha and beta subunits of the metalloendopeptidase meprin map to human chromosomes 6p and 18q, respectively

7 April 2017

1 reference

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Increased activity and expression of matrix metalloproteinase-9 in a rat model of distal colitis

7 April 2017

1 reference

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Probing the active sites and mechanisms of rat metalloproteases meprin A and B

7 April 2017

1 reference

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Cloning, expression, and chromosomal localization of the mouse meprin beta subunit

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670347

Unravelling the pathogenesis of inflammatory bowel disease

7 April 2017

1 reference

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Derivation of completely cell culture-derived mice from early-passage embryonic stem cells

7 April 2017

1 reference

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Prointerleukin-18 is activated by meprin beta in vitro and in vivo in intestinal inflammation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670347

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease

28 September 2017

1 reference

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Compartmentalised expression of meprin in small intestinal mucosa: enhanced expression in lamina propria in coeliac disease

28 September 2017

1 reference

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Involvement of IL-6 in the pathogenesis of inflammatory bowel disease and colon cancer

28 September 2017

1 reference

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Mannan-binding protein blocks the activation of metalloproteases meprin alpha and beta.

28 September 2017

1 reference

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Systemic administration of the chemokine macrophage inflammatory protein 1alpha exacerbates inflammatory bowel disease in a mouse model

28 September 2017

1 reference

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Meprin metalloprotease expression and regulation in kidney, intestine, urinary tract infections and cancer.

28 September 2017

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Expression of meprins in health and disease

28 September 2017

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Chemokine expression in IBD. Mucosal chemokine expression is unselectively increased in both ulcerative colitis and Crohn's disease.

28 September 2017

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Ulcerative colitis and Crohn's disease: distinctive gene expression profiles and novel susceptibility candidate genes

28 September 2017

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Insights from mouse models of colitis

28 September 2017

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Human N-benzoyl-L-tyrosyl-p-aminobenzoic acid hydrolase (human meprin): genomic structure of the alpha and beta subunits

28 September 2017

1 reference

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Linkage of inflammatory bowel disease to human chromosome 6p

28 September 2017

1 reference

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Identification and localization of MEP1A-like sequences (MEP1AL1-4) in the human genome

28 September 2017

1 reference

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Nonpolarized secretion of human meprin alpha in colorectal cancer generates an increased proteolytic potential in the stroma

28 September 2017

1 reference

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Erythroid cell-specific determinants of alpha-globin mRNA stability

28 September 2017

1 reference

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Dextran sulfate sodium-induced colitis occurs in severe combined immunodeficient mice.

28 September 2017

1 reference

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Selective ablation of matrix metalloproteinase-2 exacerbates experimental colitis: contrasting role of gelatinases in the pathogenesis of colitis

28 September 2017

1 reference

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Human meprin alpha and beta homo-oligomers: cleavage of basement membrane proteins and sensitivity to metalloprotease inhibitors

30 May 2018

1 reference

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Differential expression of matrix metalloproteinases and their tissue inhibitors in colon mucosa of patients with inflammatory bowel disease

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670347

Effects of dextran sulphate sodium on intestinal epithelial cells and intestinal lymphocytes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670347

Clinicopathologic study of dextran sulfate sodium experimental murine colitis.

30 May 2018

1 reference

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Deletion of the mouse meprin beta metalloprotease gene diminishes the ability of leukocytes to disseminate through extracellular matrix

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1038%2FMI.2009.3

Sequence variants in IL10, ARPC2 and multiple other loci contribute to ulcerative colitis susceptibility

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670347

Therapeutic implications of the specific inhibition of causative matrix metalloproteinases in experimental colitis induced by dextran sulphate sodium

28 November 2018

1 reference

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Enhanced survival and mucosal repair after dextran sodium sulfate-induced colitis in transgenic mice that overexpress growth hormone

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670347

Differential susceptibility of inbred mouse strains to dextran sulfate sodium-induced colitis.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2670347

Characterisation of acute murine dextran sodium sulphate colitis: cytokine profile and dose dependency

28 November 2018

1 reference

12 December 2020

Deficiency of a Kidney Metalloproteinase Activity in Inbred Mouse Strains

1 reference

12 December 2020

Fine mapping of MEP1A, the gene encoding the alpha subunit of the metalloendopeptidase meprin, to human chromosome 6P21

1 reference

12 December 2020

Assignment of Mep 1a to mouse chromosome band 17C1-D1 by in situ hybridization

1 reference

12 December 2020

Increased expression and activation of IL-12-induced Stat4 signaling in the mucosa of ulcerative colitis patients

1 reference

12 December 2020

Identifiers

DOI

10.1038/MI.2009.3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19262505%20AND%20SRC:MED&resulttype=core&format=json

Dimensions Publication ID

22 January 2020

0 references

1 reference

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22 January 2020

PubMed publication ID

19262505

1 reference