The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds (Q24657959)

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26 December 2019

review article

1 reference

title

The 2005 World Health Organization reevaluation of human and Mammalian toxic equivalency factors for dioxins and dioxin-like compounds (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16829543%20AND%20SRC:MED&resulttype=core&format=json

World Health Organization

26 December 2019

main subject

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author

Linda Birnbaum

2

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26 December 2019

Heidelore Fiedler

7

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26 December 2019

Helen Håkansson

8

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26 December 2019

Annika Hanberg

9

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26 December 2019

Martin Rose

11

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26 December 2019

Nigel J Walker

18

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26 December 2019

15

Angelika Tritscher

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26 December 2019

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Martin Van den Berg

1

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26 December 2019

Michael Denison

3

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26 December 2019

Mike De Vito

4

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26 December 2019

William Farland

5

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26 December 2019

Mark Feeley

6

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26 December 2019

Laurie Haws

10

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26 December 2019

Stephen Safe

12

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26 December 2019

Dieter Schrenk

13

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26 December 2019

Chiharu Tohyama

14

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26 December 2019

Jouko Tuomisto

16

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26 December 2019

Richard E Peterson

19

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26 December 2019

Mats Tysklind

17

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26 December 2019

language of work or name

English

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publication date

7 July 2006

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26 December 2019

published in

Toxicological Sciences

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26 December 2019

volume

93

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26 December 2019

page(s)

223-241

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26 December 2019

issue

2

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Thyroid-hormone-disrupting chemicals: evidence for dose-dependent additivity or synergism

26 December 2019

cites work

1 reference

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7 April 2017

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Flavonoids as aryl hydrocarbon receptor agonists/antagonists: effects of structure and cell context

7 April 2017

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Toxic equivalency factors (TEFs) for PCBs, PCDDs, PCDFs for humans and wildlife

7 April 2017

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Dioxin binding activities of polymorphic forms of mouse and human arylhydrocarbon receptors

7 April 2017

1 reference

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PCBs: structure-function relationships and mechanism of action

7 April 2017

1 reference

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Characterization of the Ah receptor mediating aryl hydrocarbon hydroxylase induction in the human liver cell line Hep G2

7 April 2017

1 reference

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Determination of in vitro relative potency (REP) values for mono-ortho polychlorinated biphenyls after purification with active charcoal

7 April 2017

1 reference

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Development of a refined database of mammalian relative potency estimates for dioxin-like compounds.

28 September 2017

1 reference

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Toxicological implications of polymorphisms in receptors for xenobiotic chemicals: the case of the aryl hydrocarbon receptor

28 September 2017

1 reference

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Effects of polybrominated diphenyl ethers on basal and TCDD-induced ethoxyresorufin activity and cytochrome P450-1A1 expression in MCF-7, HepG2, and H4IIE cells.

28 September 2017

1 reference

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Higher brominated diphenyl ethers and hexabromocyclododecane found in eggs of peregrine falcons (Falco peregrinus) breeding in Sweden

28 September 2017

1 reference

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Chloronaphthalenes as food-chain contaminants: a review

28 September 2017

1 reference

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Brominated dioxin-like compounds: in vitro assessment in comparison to classical dioxin-like compounds and other polyaromatic compounds

28 September 2017

1 reference

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Health effects of polybrominated dibenzo-p-dioxins (PBDDs) and dibenzofurans (PBDFs).

28 September 2017

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Toxic effects of brominated flame retardants in man and in wildlife

28 September 2017

1 reference

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Metabolism in the toxicokinetics and fate of brominated flame retardants--a review

28 September 2017

1 reference

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Evaluation of Chronic Dietary Exposure to Indole-3-Carbinol and Absorption-Enhanced 3,3'-Diindolylmethane in Sprague-Dawley Rats

28 September 2017

1 reference

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Distinct response to dioxin in an arylhydrocarbon receptor (AHR)-humanized mouse

28 September 2017

1 reference

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Polybrominated dibenzo-p-dioxins, dibenzofurans, and diphenyl ethers in Japanese human adipose tissue.

28 September 2017

1 reference

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Polymorphisms in the human AH receptor

28 September 2017

1 reference

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Identification of novel Ah receptor agonists using a high-throughput green fluorescent protein-based recombinant cell bioassay

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

Bioanalytical screening methods for dioxins and dioxin-like compounds a review of bioassay/biomarker technology

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

Inducing effects of dioxin-like polychlorinated biphenyls on CYP1A in the human hepatoblastoma cell line HepG2, the rat hepatoma cell line H4IIE, and rat primary hepatocytes: comparison of relative potencies

28 September 2017

1 reference

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Sensitivity of the SRBC PFC assay versus ELISA for detection of immunosuppression by TCDD and TCDD-like congeners

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

Dose-response relationships for induction of CYP1A1 and CYP1A2 enzyme activity in liver, lung, and skin in female mice following subchronic exposure to polychlorinated biphenyls.

28 September 2017

1 reference

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Exposure of populations to dioxins and related compounds

28 September 2017

1 reference

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Hexachlorobenzene as a possible major contributor to the dioxin activity of human milk

28 September 2017

1 reference

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Stepping backward to improve assessment of PCB congener toxicities

28 September 2017

1 reference

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Review of the biology of Quercetin and related bioflavonoids

28 September 2017

1 reference

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Synergistic effect of 2,2',4,4',5,5'-hexachlorobiphenyl and 2,3,7,8-tetrachlorodibenzo-p-dioxin on hepatic porphyrin levels in the rat.

28 September 2017

1 reference

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Polychlorinated biphenyl levels in the tissues of exposed and nonexposed humans

28 September 2017

1 reference

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The toxicokinetics and metabolism of polychlorinated dibenzo-p-dioxins (PCDDs) and dibenzofurans (PCDFs) and their relevance for toxicity.

28 September 2017

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Formation of polychlorinated dibenzofurans and dioxins during combustion, electrical equipment fires and PCB incineration

28 September 2017

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Comparative toxicology and mechanism of action of polychlorinated dibenzo-p-dioxins and dibenzofurans

28 September 2017

1 reference

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Studies on the mechanism of action of halogenated aromatic hydrocarbons

28 September 2017

1 reference

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The structure-activity relationships of halogenated biphenyls as enzyme inducers

28 September 2017

1 reference

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Possible correlation between induction modes of hepatic enzymes by PCBs and their toxicity in rats

28 September 2017

1 reference

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Indole-3-carbinol and diindolylmethane as aryl hydrocarbon (Ah) receptor agonists and antagonists in T47D human breast cancer cells

28 September 2017

1 reference

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The toxicity of brominated and mixed-halogenated dibenzo-p-dioxins and dibenzofurans: an overview.

28 September 2017

1 reference

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Immunosuppressive activities of polychlorinated dibenzofuran congeners: quantitative structure-activity relationships and interactive effects

28 September 2017

1 reference

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Effects of several dioxin-like compounds on estrogen metabolism in the malignant MCF-7 and nontumorigenic MCF-10A human mammary epithelial cell lines

28 September 2017

1 reference

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Comparison of acute toxicities of indolo[3,2-b]carbazole (ICZ) and 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in TCDD-sensitive rats

30 May 2018

1 reference

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Activation of the Ah receptor by tryptophan and tryptophan metabolites

30 May 2018

1 reference

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Limitations of the toxic equivalency factor approach for risk assessment of TCDD and related compounds

30 May 2018

1 reference

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Identification of bioaccumulating polychlorinated naphthalenes and their toxicological significance

30 May 2018

1 reference

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Development validation and problems with the toxic equivalency factor approach for risk assessment of dioxins and related compounds

30 May 2018

1 reference

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Effects of developmental exposure to indole-3-carbinol or 2,3,7,8-tetrachlorodibenzo-p-dioxin on reproductive potential of male rat offspring.

30 May 2018

1 reference

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Analysis of the four alleles of the murine aryl hydrocarbon receptor

30 May 2018

1 reference

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PCBs and PBBs: Biologic and toxic effects on C57BL/6J and DBA/2J inbred mice

30 May 2018

1 reference

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Hexabromonaphthalene contaminants of polybrominated biphenyls: chemical composition and disposition in the rat.

30 May 2018

1 reference

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Polybrominated biphenyls as aryl hydrocarbon hydroxylase inducers: structure-activity correlations

30 May 2018

1 reference

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Teratologic evaluation of hexabrominated naphthalenes in C57BL/6N mice

30 May 2018

1 reference

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Synergistic interaction of 2,3,7,8,-tetrachlorodibenzo-p-dioxin and hydrocortisone in the induction of cleft palate in mice.

30 May 2018

1 reference

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Polybrominated dibenzo-p-dioxins and related compounds: quantitative in vivo and in vitro structure-activity relationships

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

2,2',4,4',5,5'-hexachlorobiphenyl as a 2,3,7,8-tetrachlorodibenzo-p-dioxin antagonist in C57BL/6J mice

30 May 2018

1 reference

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Limited PCB antagonism of TCDD-induced malformations in mice

30 May 2018

1 reference

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Identification of polybrominated dibenzo-p-dioxins in blue mussels (Mytilus edulis) from the Baltic Sea.

30 May 2018

1 reference

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Brominated flame retardants and other organobromines in Norwegian predatory bird eggs.

28 November 2018

1 reference

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Differential expression of CYP1A, 2B, and 3A genes in the F344 rat following exposure to a polybrominated diphenyl ether mixture or individual components

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

Bio/chemical analysis of dioxin-like compounds in sediment samples from Osaka Bay, Japan

28 November 2018

1 reference

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Brominated organic contaminants in the liver and egg of the common cormorants (Phalacrocorax carbo) from Japan

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

Interaction between halogenated aromatic compounds in the Ah receptor signal transduction pathway

28 November 2018

1 reference

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Use of 2-azido-3-[125I]iodo-7,8-dibromodibenzo-p-dioxin as a probe to determine the relative ligand affinity of human versus mouse aryl hydrocarbon receptor in cultured cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

Pesticides and PCBs in sediments and fish from the Salton Sea, California, USA.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

Evaluation of toxic equivalency factors for induction of cytochromes P450 CYP1A1 and CYP1A2 enzyme activity by dioxin-like compounds

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

Polybrominated Diphenyl Ethers as Ah Receptor Agonists and Antagonists

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

Activation of the Ah receptor by extracts of dietary herbal supplements, vegetables, and fruits

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

Polychlorinated naphthalenes in foods: estimated dietary intake by the population of Catalonia, Spain

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

A mixture of dioxins, furans, and non-ortho PCBs based upon consensus toxic equivalency factors produces dioxin-like reproductive effects

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

The use of toxic equivalency factor distributions in probabilistic risk assessments for dioxins, furans, and PCBs

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

Structure-activity relationships and dose responses of polychlorinated dibenzo-p-dioxins for short-term effects in 2,3,7,8-tetrachlorodibenzo-p-dioxin-resistant and -sensitive rat strains

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

Preliminary screening of the inhibitory effect of food extracts on activation of the aryl hydrocarbon receptor induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

Polychlorinated dibenzo-p-dioxins, dibenzofurans, and polychlorinated biphenyls in human tissues, meat, fish, and wildlife samples from India

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

Disposition of polychlorinated dibenzo-p-dioxins, dibenzofurans, and non-ortho polychlorinated biphenyls in pregnant long evans rats and the transfer to offspring.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

Public health assessment of hexachlorobenzene

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

Health effects of hexachlorobenzene and the TEF approach

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

The TEF approach for hexachlorobenzene

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

Toxic equivalency factors of polychlorinated dibenzo-p-dioxins in an ovulation model: validation of the toxic equivalency concept for one aspect of endocrine disruption.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

Interactive effects of TCDD and p,p'-DDE on male reproductive tract development in in utero and lactationally exposed rats.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

The Ah receptor: a regulator of the biochemical and toxicological actions of structurally diverse chemicals

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

Polychlorinated naphthalenes and other organochlorine contaminants in human adipose and liver tissue.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

Subchronic/chronic toxicity of 1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin (HpCDD) in rats. Part II. Biochemical effects.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

Subchronic/chronic toxicity of 1,2,3,4,6,7,8-heptachlorodibenzo-p-dioxin (HpCDD) in rats. Part I. Design, general observations, hematology, and liver concentrations.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

Use of toxic equivalency factors for risk assessment for dioxins and related compounds.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

Immunosuppressive activity of polychlorinated biphenyl mixtures and congeners: nonadditive (antagonistic) interactions.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2290740

Dose-response relationships for disposition and hepatic sequestration of polyhalogenated dibenzo-p-dioxins, dibenzofurans, and biphenyls following subchronic treatment in mice

28 November 2018

1 reference

12 December 2020

Inductive and inhibitory effects of non-ortho-substituted polychlorinated biphenyls on estrogen metabolism and human cytochromes P450 1A1 and 1B1

1 reference

12 December 2020

Relative potency values derived from hepatic vitamin A reduction in male and female Sprague-Dawley rats following subchronic dietary exposure to individual polychlorinated dibenzo-p-dioxin and dibenzofuran congeners and a mixture thereof

1 reference

12 December 2020

Relative Potencies of Individual Polychlorinated Naphthalenes to Induce Dioxin-Like Responses in Fish and Mammalian In Vitro Bioassays

1 reference

12 December 2020

1 reference

12 December 2020

Polychlorinated dibenzofurans (PCDFs): effects of structure on binding to the 2,3,7,8-TCDD cytosolic receptor protein, AHH induction and toxicity

1 reference

12 December 2020

A toxic equivalency factor scale for polychlorinated dibenzofurans

1 reference

12 December 2020

Effect on tissue vitamin A levels in the rat following subchronic exposure to four individual PCB congeners (IUPAC 77, 118, 126, and 153)

1 reference

12 December 2020

Subchronic (13-week) toxicity of heptachlorodibenzo-p-dioxin in male Sprague-Dawley rats

1 reference

12 December 2020

Liver tumour promoting activity of 3,4,5,3',4'-pentachlorobiphenyl and its interaction with 2,3,7,8-tetrachlorodibenzo-p-dioxin

1 reference

12 December 2020

Interactions of polychlorinated dibenzo-p-dioxin, dibenzofuran, and biphenyl congeners for producing rainbow trout early life stage mortality

1 reference

12 December 2020

Toxicity of PCB 77 (3,3',4,4'-tetrachlorobiphenyl) and PCB 118 (2,3',4,4'5-pentachlorobiphenyl) in the rat following subchronic dietary exposure

1 reference

12 December 2020

Relative potencies of polychlorinated dibenzo-p-dioxins, dibenzofurans, and biphenyls derived from hepatic porphyrin accumulation in mice

1 reference

12 December 2020

Opposite effects of 2,2',4,4',5,5'-hexachlorobiphenyl and 2,3,7,8-tetrachlorodibenzo-p-dioxin on the antibody response to sheep erythrocytes in mice

1 reference

12 December 2020

Polychlorinated naphthalenes and other organochlorine contaminants in Swedish human milk, 1972-1992

1 reference

12 December 2020

Structure-dependent induction of CYP1A by polychlorinated biphenyls in hepatocytes of cynomolgus monkeys (Macaca fascicularis)

1 reference

12 December 2020

Synergistic interactions of 2,3,7,8-TCDD and 2,2',4,4',5,5'-hexachlorobiphenyl in C57BL/6J and DBA/2J mice: role of the Ah receptor

1 reference

12 December 2020

Assessment of biological activities of mixtures of polychlorinated dibenzo-p-dioxins: comparison between defined mixtures and their constituents

1 reference

12 December 2020

Toxicity equivalents and EPA's risk assessment of 2,3,7,8-TCDD

1 reference

12 December 2020

Relative Liver Tumour Promoting Activity and Toxicity of some Polychlorinated Dibeiizo-p-dioxin- and Dibenzofuran-Congeners in Female Sprague-Dawley Rats

1 reference

12 December 2020

Assessment of biological activities of mixtures of polychlorinated dibenzo-p-dioxins (PCDDs) and their constituents in human HepG2 cells

1 reference

12 December 2020

Teratogenicity and immunotoxicity of 3,3',4,4',5-pentachlorobiphenyl in C57BL/6 mice

1 reference

12 December 2020

Immunotoxic potencies of polychlorinated biphenyl (PCB), dibenzofuran (PCDF) and dibenzo-p-dioxin (PCDD) congeners in C57BL/6 and DBA/2 mice

1 reference

12 December 2020

Promotion of preneoplastic foci in rat liver with 2,3,7,8-tetrachlorodibenzo-p-dioxin, 1,2,3,4,6,7,8-heptachloro-dibenzo-p-dioxin and a defined mixture of 49 polychlorinated dibenzo-p-dioxins

1 reference

12 December 2020

Toxicity equivalency factors for PCBs?

1 reference

12 December 2020

Toxic equivalency factors for dioxin-like PCBs

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFL055

7 January 2021

Relative Potencies of Individual Polychlorinated Naphthalenes and Halowax Mixtures To Induce Ah Receptor-Mediated Responses

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFL055

7 January 2021

Content of potentially anticarcinogenic flavonoids of 28 vegetables and 9 fruits commonly consumed in the Netherlands

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFL055

7 January 2021

Content of potentially anticarcinogenic flavonoids of tea infusions, wines, and fruit juices

1 reference

https://api.crossref.org/works/10.1093%2FTOXSCI%2FKFL055

7 January 2021

Identifiers

DOI

10.1093/TOXSCI/KFL055

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16829543%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16829543%20AND%20SRC:MED&resulttype=core&format=json

26 December 2019

2 references