Effect of inositol hexakisphosphate kinase 2 on transforming growth factor beta-activated kinase 1 and NF-kappaB activation (Q24670467)

2

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Joseph A Lupica

3

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Zhuo Tang

4

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Heidi Schmidt

5

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Joseph A DiDonato

6

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Daniel J Lindner

Journal of Biological Chemistry

7

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language of work or name

English

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publication date

25 May 2007

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published in

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volume

282

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issue

21

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page(s)

15349-56

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cites work

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Inositol hexakisphosphate kinase 2 sensitizes ovarian carcinoma cells to multiple cancer therapeutics

7 April 2017

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The alpha and beta subunits of IkappaB kinase (IKK) mediate TRAF2-dependent IKK recruitment to tumor necrosis factor (TNF) receptor 1 in response to TNF

21 January 2018

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Inositol hexakisphosphate kinase 2 mediates growth suppressive and apoptotic effects of interferon-beta in ovarian carcinoma cells

7 April 2017

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Tumor necrosis factor (TNF)-mediated kinase cascades: bifurcation of nuclear factor-kappaB and c-jun N-terminal kinase (JNK/SAPK) pathways at TNF receptor-associated factor 2

7 April 2017

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A cytokine-responsive IkappaB kinase that activates the transcription factor NF-kappaB

7 April 2017

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Structural basis for self-association and receptor recognition of human TRAF2

7 April 2017

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TAK1, but not TAB1 or TAB2, plays an essential role in multiple signaling pathways in vivo

7 April 2017

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TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90

7 April 2017

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Activation by IKKalpha of a second, evolutionary conserved, NF-kappa B signaling pathway

7 April 2017

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Critical roles of TRAF2 and TRAF5 in tumor necrosis factor-induced NF-kappa B activation and protection from cell death

7 April 2017

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NF-kappaB activation by tumour necrosis factor requires the Akt serine-threonine kinase

7 April 2017

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Direct phosphorylation of IkappaB by IKKalpha and IKKbeta: discrimination between free and NF-kappaB-bound substrate

7 April 2017

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Binding of inositol phosphate to DNA-PK and stimulation of double-strand break repair

7 April 2017

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Targeted disruption of Traf5 gene causes defects in CD40- and CD27-mediated lymphocyte activation

7 April 2017

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Tumor necrosis factor receptor-associated factors (TRAFs)--a family of adapter proteins that regulates life and death

7 April 2017

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Early lethality, functional NF-kappaB activation, and increased sensitivity to TNF-induced cell death in TRAF2-deficient mice

7 April 2017

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New colorimetric cytotoxicity assay for anticancer-drug screening

7 April 2017

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Evidence that TNF-TNFR1-TRADD-TRAF2-RIP-TAK1-IKK pathway mediates constitutive NF-kappaB activation and proliferation in human head and neck squamous cell carcinoma

7 April 2017

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TRAF6 is required for TRAF2-dependent CD40 signal transduction in nonhemopoietic cells

28 September 2017

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Phosphorylation of proteins by inositol pyrophosphates

28 September 2017

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Inositol hexakisphosphate kinase-2, a physiologic mediator of cell death

28 September 2017

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Visualization of inositol phosphate-dependent mobility of Ku: depletion of the DNA-PK cofactor InsP6 inhibits Ku mobility

28 September 2017

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Inositol pyrophosphates regulate endocytic trafficking

28 September 2017

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The Toll-receptor family and control of innate immunity

28 September 2017

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Assaying for I kappa B kinase activity

28 September 2017

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Inositol pyrophosphates mediate chemotaxis in Dictyostelium via pleckstrin homology domain-PtdIns(3,4,5)P3 interactions

30 May 2018

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Transfected rat cMOAT is functionally expressed on the apical membrane in Madin-Darby canine kidney (MDCK) cells

21 January 2018

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Direct Phosphorylation of IB by IKK and IKK: Discrimination Between Free and NF-B-Bound Substrate

21 January 2018

1 reference

Crossref

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TRAF2 is essential for JNK but not NF-kappaB activation and regulates lymphocyte proliferation and survival

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17379600

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17379600