A possible pharmacological explanation for quinacrine failure to treat prion diseases: pharmacokinetic investigations in a ovine model of scrapie (Q24670616)

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English	A possible pharmacological explanation for quinacrine failure to treat prion diseases: pharmacokinetic investigations in a ovine model of scrapie	scientific article

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scholarly article

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7 January 2020

A possible pharmacological explanation for quinacrine failure to treat prion diseases: pharmacokinetic investigations in a ovine model of scrapie (English)

1 reference

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7 January 2020

prion protein family

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pharmacokinetics

1 reference

based on heuristic

inferred from title

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based on heuristic

inferred from title

Véronique Gayrard

1

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7 January 2020

Nicole Picard-Hagen

2

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7 January 2020

author name string

Catherine Viguié

3

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7 January 2020

Valerie Laroute

4

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7 January 2020

Olivier Andréoletti

5

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7 January 2020

Pierre-Louis Toutain

6

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7 January 2020

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publication date

1 February 2005

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7 January 2020

British Journal of Pharmacology

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7 January 2020

144

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7 January 2020

3

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7 January 2020

386-393

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7 January 2020

Evaluation of quinacrine treatment for prion diseases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576015

7 April 2017

Lysosomotropic agents and cysteine protease inhibitors inhibit scrapie-associated prion protein accumulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576015

7 April 2017

Uptake and efflux of quinacrine, a candidate for the treatment of prion diseases, at the blood-brain barrier

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576015

28 September 2017

Considerations in the use of cerebrospinal fluid pharmacokinetics to predict brain target concentrations in the clinical setting: implications of the barriers between blood and brain.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576015

28 September 2017

Acridine and phenothiazine derivatives as pharmacotherapeutics for prion disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576015

28 September 2017

4-Aminoquinolines--past, present, and future: a chemical perspective

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576015

28 September 2017

A mutant prion protein displays an aberrant membrane association when expressed in cultured cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576015

28 September 2017

Proteinase-resistant prion protein accumulation in Syrian hamster brain correlates with regional pathology and scrapie infectivity

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576015

28 September 2017

Antimalarial drug quinacrine binds to C-terminal helix of cellular prion protein

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576015

30 May 2018

Application of Akaike's information criterion (AIC) in the evaluation of linear pharmacokinetic equations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576015

30 May 2018

Results of quinacrine administration to patients with Creutzfeldt-Jakob disease.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576015

28 November 2018

New perspectives for prion therapeutics meeting. Prion disease treatment's early promise unravels.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576015

28 November 2018

Quinacrine does not prolong survival in a murine Creutzfeldt-Jakob disease model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576015

28 November 2018

Corticoid concentrations are increased in the plasma and urine of ewes with naturally occurring scrapie.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1576015

28 November 2018

[Prospects of the therapeutic approaches to Creutzfeldt-Jakob disease: a clinical trial of antimalarial, quinacrine]

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Pharmacokinetic studies on quinacrine following intrauterine administration to cynomolgus monkeys

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Determination of quinacrine (mepacrine) in plasma by high-performance liquid chromatography with fluorimetric detection

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Precise targeting of the pathology of the sialoglycoprotein, PrP, and vacuolar degeneration in mouse scrapie

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A prion protein cycles between the cell surface and an endocytic compartment in cultured neuroblastoma cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/15655516

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1038/SJ.BJP.0706072

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Europe PubMed Central

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7 January 2020

1 reference

Europe PubMed Central

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7 January 2020

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15655516%20AND%20SRC:MED&resulttype=core&format=json

7 January 2020

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