Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes (Q24671911)

Journal of Clinical Investigation

Europe PubMed Central

title

Mixed messages: modulation of inflammation and immune responses by prostaglandins and thromboxanes (English)

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S L Tilley

1

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T M Coffman

series ordinal

2

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B H Koller

series ordinal

3

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language of work or name

English

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publication date

July 2001

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published in

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volume

108

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issue

1

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page(s)

15-23

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cites work

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A prostaglandin J2 metabolite binds peroxisome proliferator-activated receptor gamma and promotes adipocyte differentiation

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The febrile response to lipopolysaccharide is blocked in cyclooxygenase-2(-/-), but not in cyclooxygenase-1(-/-) mice

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Altered pain perception and inflammatory response in mice lacking prostacyclin receptor

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Prostaglandin synthase-1 and prostaglandin synthase-2 are coupled to distinct phospholipases for the generation of prostaglandin D2 in activated mast cells

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IgE production by normal human lymphocytes is induced by interleukin 4 and suppressed by interferons gamma and alpha and prostaglandin E2

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Enhancement of acute allergic inflammation by indomethacin is reversed by prostaglandin E2: apparent correlation with in vivo modulation of mediator release

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Renal abnormalities and an altered inflammatory response in mice lacking cyclooxygenase II.

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Specific suppression by prostaglandin E2 of activation-induced apoptosis of human CD4+CD8+ T lymphoblasts.

28 September 2017

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Prostaglandin E2 down-regulates the expression of HLA-DR antigen in human colon adenocarcinoma cell lines

28 September 2017

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Prostaglandin-H-synthase isozyme expression in normal and neoplastic human skin

28 September 2017

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Cyclooxygenase 1 contributes to inflammatory responses in rats and mice: implications for gastrointestinal toxicity.

30 May 2018

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The prostaglandin receptor EP4 triggers remodelling of the cardiovascular system at birth.

30 May 2018

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In situ hybridization studies of prostacyclin receptor mRNA expression in various mouse organs

30 May 2018

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Prostaglandin synthase 2 gene disruption causes severe renal pathology in the mouse.

30 May 2018

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Prostaglandin E2 inhibits B lymphocyte activation by a cAMP-dependent mechanism: PGE-inducible regulatory proteins

30 May 2018

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Thromboxane A2 receptor blocking abrogates donor-specific unresponsiveness to renal allografts induced by thymic recognition of major histocompatibility allopeptides

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209346

Prostaglandin E2 acts at two distinct pathways of T lymphocyte activation: inhibition of interleukin 2 production and down-regulation of transferrin receptor expression

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209346

Effect of inhibitors of prostaglandin synthesis and prostaglandins E2 and F2alpha on the immunologic release of mediators of inflammation from actively sensitized guinea-pig lung

30 May 2018

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Identification of specific EP receptors responsible for the hemodynamic effects of PGE2.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209346

Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration.

28 November 2018

1 reference

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Thromboxane A2 receptor is highly expressed in mouse immature thymocytes and mediates DNA fragmentation and apoptosis

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=209346

Inducible cyclooxygenase may have anti-inflammatory properties

28 November 2018

1 reference

12 December 2020

Differential Regulation of Prostaglandin E2 and Thromboxane A2 Production in Human Monocytes: Implications for the Use of Cyclooxygenase Inhibitors

1 reference

12 December 2020

Cyclooxygenase inhibition increases interleukin 5 and interleukin 13 production and airway hyperresponsiveness in allergic mice

1 reference

12 December 2020

The genetic ablation of cyclooxygenase 2 prevents the development of autoimmune arthritis

1 reference

12 December 2020

Prostaglandin E2 as a modulator of lymphocyte mediated inflammatory and humoral responses

1 reference

12 December 2020

Prostaglandin D2 as a mediator of allergic asthma

1 reference

12 December 2020

Thromboxane augmentation of alloreactive T cell function

1 reference

12 December 2020

Regulation of IL-4 and IL-5 secretion by histamine and PGE2

1 reference

12 December 2020

Two Gs-coupled prostaglandin E receptor subtypes, EP2 and EP4, differ in desensitization and sensitivity to the metabolic inactivation of the agonist

1 reference

12 December 2020

Segregated coupling of phospholipases A2, cyclooxygenases, and terminal prostanoid synthases in different phases of prostanoid biosynthesis in rat peritoneal macrophages

1 reference

12 December 2020

Salt-sensitive hypertension and reduced fertility in mice lacking the prostaglandin EP2 receptor

1 reference

12 December 2020

Identifiers

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2342001

2342001

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