Rapamycin is efficacious against primary effusion lymphoma (PEL) cell lines in vivo by inhibiting autocrine signaling (Q24673299)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17082322%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

title

Rapamycin is efficacious against primary effusion lymphoma (PEL) cell lines in vivo by inhibiting autocrine signaling (English)

1 reference

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21 December 2019

0 references

1 reference

primary effusion lymphoma

1 reference

1

1 reference

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21 December 2019

Michelle R Staudt

4

1 reference

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21 December 2019

Dirk Dittmer

10

1 reference

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21 December 2019

author name string

Debasmita Roy

2

1 reference

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21 December 2019

Ling Wang

3

1 reference

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21 December 2019

Farnaz D Fakhari

5

1 reference

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21 December 2019

Dhavalkumar D Patel

6

1 reference

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21 December 2019

David Henry

7

1 reference

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21 December 2019

William J Harrington

8

1 reference

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21 December 2019

Blossom A Damania

9

1 reference

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21 December 2019

language of work or name

English

0 references

publication date

2 November 2006

1 reference

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21 December 2019

1 reference

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21 December 2019

volume

109

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21 December 2019

page(s)

2165-2173

1 reference

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21 December 2019

issue

5

1 reference

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Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex

21 December 2019

cites work

1 reference

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Mammalian TOR complex 2 controls the actin cytoskeleton and is rapamycin insensitive

7 April 2017

1 reference

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Enhanced sensitivity of PTEN-deficient tumors to inhibition of FRAP/mTOR.

7 April 2017

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The tumor microenvironment controls primary effusion lymphoma growth in vivo

7 April 2017

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Post-transplant Kaposi sarcoma originates from the seeding of donor-derived progenitors

7 April 2017

1 reference

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Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma

7 April 2017

1 reference

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Kaposi's sarcoma-associated herpesvirus-like DNA sequences in multicentric Castleman's disease

7 April 2017

1 reference

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The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor as a therapeutic target for the treatment of Kaposi's sarcoma.

7 April 2017

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The Akt-mTOR tango and its relevance to cancer

28 September 2017

1 reference

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Activation of mammalian target of rapamycin in transformed B lymphocytes is nutrient dependent but independent of Akt, mitogen-activated protein kinase/extracellular signal-regulated kinase kinase, insulin growth factor-I, and serum.

28 September 2017

1 reference

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Kaposi's sarcoma in the era of HAART-an update on mechanisms, diagnostics and treatment.

28 September 2017

1 reference

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Inhibition of phosphatidylinositol 3'-kinase/AKT signaling promotes apoptosis of primary effusion lymphoma cells.

28 September 2017

1 reference

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Sirolimus for Kaposi's sarcoma in renal-transplant recipients

28 September 2017

1 reference

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Restraining PI3K: mTOR signalling goes back to the membrane.

28 September 2017

1 reference

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Oncogenic gamma-herpesviruses: comparison of viral proteins involved in tumorigenesis

28 September 2017

1 reference

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Kaposi sarcoma herpesvirus-induced cellular reprogramming contributes to the lymphatic endothelial gene expression in Kaposi sarcoma.

28 September 2017

1 reference

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Akt plays a central role in sarcomagenesis induced by Kaposi's sarcoma herpesvirus-encoded G protein-coupled receptor

28 September 2017

1 reference

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The K1 protein of Kaposi's sarcoma-associated herpesvirus activates the Akt signaling pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1801055

Will mTOR inhibitors make it as cancer drugs?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1801055

Kaposi's sarcoma-associated herpesvirus-infected primary effusion lymphoma has a plasma cell gene expression profile

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1801055

Rapamycin inhibits the interleukin 10 signal transduction pathway and the growth of Epstein Barr virus B-cell lymphomas

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1801055

Human herpesvirus 8-encoded vGPCR activates nuclear factor of activated T cells and collaborates with human immunodeficiency virus type 1 Tat.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1801055

Spectrum of Kaposi's sarcoma-associated herpesvirus, or human herpesvirus 8, diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1801055

Charting latency transcripts in Kaposi's sarcoma-associated herpesvirus by whole-genome real-time quantitative PCR

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1801055

4E-binding proteins, the suppressors of eukaryotic initiation factor 4E, are down-regulated in cells with acquired or intrinsic resistance to rapamycin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1801055

An inhibitor of mTOR reduces neoplasia and normalizes p70/S6 kinase activity in Pten+/- mice

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1801055

A role of the kinase mTOR in cellular transformation induced by the oncoproteins P3k and Akt.

28 September 2017

1 reference

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p53 inhibition by the LANA protein of KSHV protects against cell death

28 September 2017

1 reference

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Human interleukin-6 is in vivo an autocrine growth factor for human herpesvirus-8-infected malignant B lymphocytes

28 September 2017

1 reference

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Identification of human herpesvirus 8-specific cytotoxic T-cell responses.

28 September 2017

1 reference

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Constitutive cytokine production by primary effusion (body cavity-based) lymphoma-derived cell lines

28 September 2017

1 reference

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Distribution of human herpesvirus-8 latently infected cells in Kaposi's sarcoma, multicentric Castleman's disease, and primary effusion lymphoma

28 September 2017

1 reference

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A cluster of latently expressed genes in Kaposi's sarcoma-associated herpesvirus

28 September 2017

1 reference

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Human interferon-gamma-inducible protein 10 (IP-10) inhibits constitutive signaling of Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor

28 September 2017

1 reference

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Kaposi's sarcoma-associated herpesvirus gene expression in endothelial (spindle) tumor cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1801055

Establishment and characterization of a primary effusion (body cavity-based) lymphoma cell line (BC-3) harboring kaposi's sarcoma-associated herpesvirus (KSHV/HHV-8) in the absence of Epstein-Barr virus.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1801055

Human herpesvirus-8/Kaposi's sarcoma-associated herpesvirus is a new transmissible virus that infects B cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1801055

Detection of Kaposi sarcoma associated herpesvirus in peripheral blood of HIV-infected individuals and progression to Kaposi's sarcoma

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1801055

Feasibility of drug screening with panels of human tumor cell lines using a microculture tetrazolium assay

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1801055

The natural history and molecular heterogeneity of HIV-associated primary malignant lymphomatous effusions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1801055

Real-time quantitative PCR analysis of viral transcription.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1801055

Expression of p53 and human herpesvirus-8 (HHV-8)-encoded latency-associated nuclear antigen with inhibition of apoptosis in HHV-8-associated malignancies

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1801055

Angiogenesis and hematopoiesis induced by Kaposi's sarcoma-associated herpesvirus-encoded interleukin-6.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1801055

Mechanisms of growth control of Kaposi's sarcoma-associated herpes virus-associated primary effusion lymphoma cells.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1801055

Immortalization of primary endothelial cells by the K1 protein of Kaposi's sarcoma-associated herpesvirus.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1801055

Lymphatic reprogramming of blood vascular endothelium by Kaposi sarcoma–associated herpesvirus

28 November 2018

1 reference

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mTOR inhibition reverses Akt-dependent prostate intraepithelial neoplasia through regulation of apoptotic and HIF-1-dependent pathways

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1801055

Gene expression profile analysis of AIDS-related primary effusion lymphoma (PEL) suggests a plasmablastic derivation and identifies PEL-specific transcripts.

28 November 2018

1 reference

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Inhibition of the mammalian target of rapamycin sensitizes U87 xenografts to fractionated radiation therapy.

28 November 2018

1 reference

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Viral IL-6-induced cell proliferation and immune evasion of interferon activity

28 November 2018

1 reference

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Prevalence, incidence and correlates of HHV-8/KSHV infection and Kaposi's sarcoma in renal and liver transplant recipients.

28 November 2018

1 reference

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Biochemical correlates of mTOR inhibition by the rapamycin ester CCI-779 and tumor growth inhibition

28 November 2018

1 reference

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Detection of human herpesvirus-8 DNA in kidney allografts prior to the development of Kaposi's sarcoma

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1801055

Immunosuppression, timing of human herpesvirus 8 infection, and risk of Kaposi's sarcoma among human immunodeficiency virus type 1-infected persons and transplant recipients

28 November 2018

1 reference

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Involvement of interleukin-10 (IL-10) and viral IL-6 in the spontaneous growth of Kaposi's sarcoma herpesvirus-associated infected primary effusion lymphoma cells

28 November 2018

1 reference

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Human herpes virus-8 and other risk factors for Kaposi's sarcoma in kidney transplant recipients. Groupe Cooperatif de Transplantation d' Ile de France (GCIF).

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1801055

Posttransplantation Plasmacytic Proliferations Related to Kaposi's Sarcoma–Associated Herpesvirus

28 November 2018

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12 December 2020

Transcription profile of Kaposi's sarcoma-associated herpesvirus in primary Kaposi's sarcoma lesions as determined by real-time PCR arrays

1 reference

12 December 2020

Kaposi's sarcoma-associated herpesvirus infects endothelial and spindle cells

1 reference

12 December 2020

Primary-Effusion Lymphoma and Kaposi's Sarcoma in a Cardiac-Transplant Recipient

1 reference

12 December 2020

Transmission of human herpesvirus 8 infection from renal-transplant donors to recipients

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12 December 2020

Relationship of HHV8 replication and Kaposi's sarcoma after solid organ transplantation

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12 December 2020

10.1182/BLOOD-2006-06-028092

Identifiers

DOI

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17082322%20AND%20SRC:MED&resulttype=core&format=json

21 December 2019

1 reference

2 references

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21 December 2019

2 references