Human herpesvirus 8-encoded vGPCR activates nuclear factor of activated T cells and collaborates with human immunodeficiency virus type 1 Tat. (Q34976938)

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English	Human herpesvirus 8-encoded vGPCR activates nuclear factor of activated T cells and collaborates with human immunodeficiency virus type 1 Tat.	scientific article

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3 November 2019

Human herpesvirus 8-encoded vGPCR activates nuclear factor of activated T cells and collaborates with human immunodeficiency virus type 1 Tat (English)

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3 November 2019

G protein-coupled receptor

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1 reference

based on heuristic

inferred from title

Kaposi's sarcoma-associated herpesvirus

object named as

Human herpesvirus 8

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Ricardo A. Feldman

8

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3 November 2019

author name string

Shibani Pati

1

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3 November 2019

James S Foulke

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Oxana Barabitskaya

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Jynho Kim

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B C Nair

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David Hone

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Jennifer Smart

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Marvin Reitz

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1 May 2003

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3 November 2019

Journal of Virology

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3 November 2019

77

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5759-5773

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3 November 2019

describes a project that uses

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Kaposi's sarcoma-like tumors in a human herpesvirus 8 ORF74 transgenic mouse

1 reference

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8 July 2018

A Tat subunit vaccine confers protective immunity against the immune-modulating activity of the human immunodeficiency virus type-1 Tat protein in mice

1 reference

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8 July 2018

HIV-1-Tat protein activates phosphatidylinositol 3-kinase/ AKT-dependent survival pathways in Kaposi's sarcoma cells

1 reference

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8 July 2018

HIV-1 infection of primary effusion lymphoma cell line triggers Kaposi's sarcoma-associated herpesvirus (KSHV) reactivation

1 reference

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8 July 2018

Kaposi's sarcoma-associated herpesvirus-encoded G protein-coupled receptor ORF74 constitutively activates p44/p42 MAPK and Akt via G(i) and phospholipase C-dependent signaling pathways

1 reference

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Activated glycogen synthase-3 beta suppresses cardiac hypertrophy in vivo

1 reference

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8 July 2018

Activation of NF-kappaB by the human herpesvirus 8 chemokine receptor ORF74: evidence for a paracrine model of Kaposi's sarcoma pathogenesis

1 reference

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G-protein-coupled receptors and signaling networks: emerging paradigms.

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8 July 2018

Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor constitutively activates NF-kappa B and induces proinflammatory cytokine and chemokine production via a C-terminal signaling determinant

1 reference

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8 July 2018

Partners in transcription: NFAT and AP-1.

1 reference

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8 July 2018

Induction of human immunodeficiency virus 1 replication by human herpesvirus 8.

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8 July 2018

Targeted inhibition of calcineurin signaling blocks calcium-dependent reactivation of Kaposi sarcoma-associated herpesvirus

1 reference

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8 July 2018

The Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor promotes endothelial cell survival through the activation of Akt/protein kinase B.

1 reference

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8 July 2018

The Kaposi's sarcoma-associated herpes virus G protein-coupled receptor up-regulates vascular endothelial growth factor expression and secretion through mitogen-activated protein kinase and p38 pathways acting on hypoxia-inducible factor 1alpha

1 reference

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8 July 2018

Requirement for glycogen synthase kinase-3beta in cell survival and NF-kappaB activation

1 reference

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8 July 2018

Mechanisms of action of cyclosporine.

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8 July 2018

Induction of HHV-8 lytic cycle replication by inflammatory cytokines produced by HIV-1-infected T cells

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8 July 2018

Manipulating immune responses with immunosuppressive agents that target NFAT.

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FK506, an immunosuppressant targeting calcineurin function

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8 July 2018

Calcineurin-mediated hypertrophy protects cardiomyocytes from apoptosis in vitro and in vivo: An apoptosis-independent model of dilated heart failure

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8 July 2018

Transgenic expression of the chemokine receptor encoded by human herpesvirus 8 induces an angioproliferative disease resembling Kaposi's sarcoma

1 reference

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8 July 2018

beta-catenin signaling and cancer

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8 July 2018

Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A.

1 reference

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8 July 2018

Human immunodeficiency virus-1 (HIV-1)-Tat protein promotes migration of acquired immunodeficiency syndrome-related lymphoma cells and enhances their adhesion to endothelial cells

1 reference

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8 July 2018

Perspective on Kaposi's sarcoma: facts, concepts, and conjectures

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8 July 2018

Inflammatory cytokines synergize with the HIV-1 Tat protein to promote angiogenesis and Kaposi's sarcoma via induction of basic fibroblast growth factor and the alpha v beta 3 integrin

1 reference

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8 July 2018

Human immunodeficiency virus type 1 tat protein activates transcription factor NF-kappaB through the cellular interferon-inducible, double-stranded RNA-dependent protein kinase, PKR

1 reference

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8 July 2018

Expression of the open reading frame 74 (G-protein-coupled receptor) gene of Kaposi's sarcoma (KS)-associated herpesvirus: implications for KS pathogenesis

1 reference

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8 July 2018

Deregulated signal transduction by the K1 gene product of Kaposi's sarcoma-associated herpesvirus

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8 July 2018

Reciprocal modulatory interaction between human immunodeficiency virus type 1 Tat and transcription factor NFAT1.

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8 July 2018

Vascular endothelial growth factor activates nuclear factor of activated T cells in human endothelial cells: a role for tissue factor gene expression.

1 reference

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8 July 2018

Agonists and inverse agonists for the herpesvirus 8-encoded constitutively active seven-transmembrane oncogene product, ORF-74

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8 July 2018

Chemokines activate Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor in mammalian cells in culture

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8 July 2018

Identification of an immunoreceptor tyrosine-based activation motif of K1 transforming protein of Kaposi's sarcoma-associated herpesvirus

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8 July 2018

Human interferon-gamma-inducible protein 10 (IP-10) inhibits constitutive signaling of Kaposi's sarcoma-associated herpesvirus G protein-coupled receptor

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8 July 2018

Activation of Akt/protein kinase B by G protein-coupled receptors. A role for alpha and beta gamma subunits of heterotrimeric G proteins acting through phosphatidylinositol-3-OH kinasegamma.

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8 July 2018

Deregulation of cell growth by the K1 gene of Kaposi's sarcoma-associated herpesvirus

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8 July 2018

Tropism of human herpesvirus 8 for peripheral blood lymphocytes in patients with Castleman's disease

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8 July 2018

G-protein-coupled receptor of Kaposi's sarcoma-associated herpesvirus is a viral oncogene and angiogenesis activator

1 reference

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8 July 2018

Extracellular HIV-1 Tat protein activates phosphatidylinositol 3- and Akt/PKB kinases in CD4+ T lymphoblastoid Jurkat cells

1 reference

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8 July 2018

HIV-1 Tat protein exits from cells via a leaderless secretory pathway and binds to extracellular matrix-associated heparan sulfate proteoglycans through its basic region

1 reference

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8 July 2018

Monocytes in Kaposi's sarcoma lesions are productively infected by human herpesvirus 8.

1 reference

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8 July 2018

Role of Fas ligand (CD95L) in immune escape: the tumor cell strikes back

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8 July 2018

Transcription factors of the NFAT family: regulation and function

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8 July 2018

The beta-core fragment of human chorionic gonadotrophin inhibits growth of Kaposi's sarcoma-derived cells and a new immortalized Kaposi's sarcoma cell line

1 reference

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Characterization of a chemokine receptor-related gene in human herpesvirus 8 and its expression in Kaposi's sarcoma

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8 July 2018

Nuclear export of NF-ATc enhanced by glycogen synthase kinase-3

1 reference

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8 July 2018

PI3K: downstream AKTion blocks apoptosis

1 reference

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8 July 2018

Regulation of neuronal survival by the serine-threonine protein kinase Akt

1 reference

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8 July 2018

Human herpesvirus KSHV encodes a constitutively active G-protein-coupled receptor linked to cell proliferation

1 reference

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8 July 2018

Kaposi's sarcoma-associated herpesvirus gene expression in endothelial (spindle) tumor cells

1 reference

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8 July 2018

Kaposi's sarcoma and non-Hodgkin's lymphoma following the diagnosis of AIDS. Multistate AIDS/Cancer Match Study Group

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8 July 2018

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8 July 2018

Release, uptake, and effects of extracellular human immunodeficiency virus type 1 Tat protein on cell growth and viral transactivation

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8 July 2018

Glycogen synthase kinase 3 phosphorylates Jun family members in vitro and negatively regulates their transactivating potential in intact cells

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8 July 2018

Human immunodeficiency virus type-1 tat enhances interleukin-2 promoter activity through synergism with phorbol ester and calcium-mediated activation of the NF-AT cis-regulatory motif

1 reference

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8 July 2018

Identification of herpesvirus-like DNA sequences in AIDS-associated Kaposi's sarcoma

1 reference

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8 July 2018

Kaposi's sarcoma-associated herpesvirus-like DNA sequences in AIDS-related body-cavity-based lymphomas

1 reference

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8 July 2018

The Tat protein of human immunodeficiency virus type 1, a growth factor for AIDS Kaposi sarcoma and cytokine-activated vascular cells, induces adhesion of the same cell types by using integrin receptors recognizing the RGD amino acid sequence

1 reference

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8 July 2018

Regulation of granulocyte-macrophage colony-stimulating factor and E-selectin expression in endothelial cells by cyclosporin A and the T-cell transcription factor NFAT.

1 reference

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8 July 2018

Angiogenic properties of human immunodeficiency virus type 1 Tat protein

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8 July 2018

Cytokines from activated T cells induce normal endothelial cells to acquire the phenotypic and functional features of AIDS-Kaposi's sarcoma spindle cells.

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8 July 2018

Immunosuppressive drugs prevent a rapid dephosphorylation of transcription factor NFAT1 in stimulated immune cells

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8 July 2018

Cellular uptake of the tat protein from human immunodeficiency virus

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8 July 2018

Tat protein of HIV-1 stimulates growth of cells derived from Kaposi's sarcoma lesions of AIDS patients

1 reference

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8 July 2018

Lithium blocks the PKB and GSK3 dephosphorylation induced by ceramide through protein phosphatase-2A.

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26 October 2018

Kaposi's sarcoma in the Gambia, West Africa is less frequent in human immunodeficiency virus type 2 than in human immunodeficiency virus type 1 infection despite a high prevalence of human herpesvirus 8.

1 reference

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26 October 2018

gamma-Interferon produced by CD8+ T cells infiltrating Kaposi's sarcoma induces spindle cells with angiogenic phenotype and synergy with human immunodeficiency virus-1 Tat protein: an immune response to human herpesvirus-8 infection?

1 reference

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26 October 2018

Herpes-like DNA sequences in a body-cavity-based lymphoma in an HIV-negative patient

1 reference

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26 October 2018

Infection of Circulating CD34+ Cells by HHV-8 in Patients with Kaposi’s Sarcoma

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9 December 2018

An adhesion assay using minimal shear force to remove nonadherent cells

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12 December 2020

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Efficient and rapid induction of a chronic myelogenous leukemia-like myeloproliferative disease in mice receiving P210 bcr/abl-transduced bone marrow

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12 December 2020

based on heuristic

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The enigmas of Kaposi's sarcoma

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of Kaposi's sarcoma cells in recruitment of circulating leukocytes: implications in pathogenesis

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based on heuristic

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Human herpesvirus type 8 DNA sequences in cell-free plasma and mononuclear cells of Kaposi's sarcoma patients

1 reference

https://pubmed.ncbi.nlm.nih.gov/12719569

12 December 2020

based on heuristic

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G-Protein-coupled receptors and Fcgamma-receptors mediate activation of Akt/protein kinase B in human phagocytes

1 reference

https://pubmed.ncbi.nlm.nih.gov/12719569

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

HIV Type 1 Tat Protein Is a Survival Factor for Kaposi's Sarcoma and Endothelial Cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12719569

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

T cell-mediated signaling to vascular endothelium: induction of cytokines, chemokines, and tissue factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/12719569

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Kaposi's sarcoma: a comparison of classical, endemic, and epidemic forms

1 reference

https://pubmed.ncbi.nlm.nih.gov/12719569

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1128/JVI.77.10.5759-5773.2003

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12719569%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12719569%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

1 reference

Europe PubMed Central

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12719569%20AND%20SRC:MED&resulttype=core&format=json

3 November 2019

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