Molecular mechanisms of invadopodium formation: the role of the N-WASP-Arp2/3 complex pathway and cofilin (Q24678564)

plasma membrane bounded cell projection organization

GO:1905929

1 reference

positive regulation of plasma membrane bounded cell projection assembly

GO:1905863

1 reference

regulation of plasma membrane bounded cell projection assembly

GO:1905926

1 reference

plasma membrane bounded cell projection assembly

GO:1905924

1 reference

negative regulation of plasma membrane bounded cell projection assembly

GO:1905877

1 reference

cellular component disassembly

GO:1905925

1 reference

negative regulation of cell projection organization

GO:1905878

1 reference

regulation of plasma membrane bounded cell projection organization

GO:1905928

1 reference

1 reference

11

John Condeelis

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author name string

Hideki Yamaguchi

1

0 references

Mike Lorenz

2

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Stephan Kempiak

3

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Corina Sarmiento

4

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Salvatore Coniglio

5

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Marc Symons

6

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Jeffrey Segall

7

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Robert Eddy

8

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Hiroaki Miki

9

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Tadaomi Takenawa

Cortactin interacts with WIP in regulating Arp2/3 activation and membrane protrusion

10

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language of work or name

English

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publication date

31 January 2005

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published in

Journal of Cell Biology

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volume

168

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page(s)

441-52

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issue

3

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cites work

1 reference

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Podosomes display actin turnover and dynamic self-organization in osteoclasts expressing actin-green fluorescent protein

7 April 2017

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A novel neural Wiskott-Aldrich syndrome protein (N-WASP) binding protein, WISH, induces Arp2/3 complex activation independent of Cdc42

7 April 2017

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Wiskott-Aldrich syndrome protein regulates podosomes in primary human macrophages

7 April 2017

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WAVE, a novel WASP-family protein involved in actin reorganization induced by Rac

7 April 2017

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Cellular motility driven by assembly and disassembly of actin filaments

7 April 2017

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Phosphatidylinositol 4,5-biphosphate (PIP2)-induced vesicle movement depends on N-WASP and involves Nck, WIP, and Grb2

7 April 2017

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Essential role of neural Wiskott-Aldrich syndrome protein in podosome formation and degradation of extracellular matrix in src-transformed fibroblasts

7 April 2017

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Nck and phosphatidylinositol 4,5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway

7 April 2017

1 reference

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A complex of N-WASP and WIP integrates signalling cascades that lead to actin polymerization

7 April 2017

1 reference

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Synergistic interaction between the Arp2/3 complex and cofilin drives stimulated lamellipod extension

7 April 2017

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WAVE2 is required for directed cell migration and cardiovascular development

7 April 2017

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Tumour-cell invasion and migration: diversity and escape mechanisms

7 April 2017

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Dissemination and growth of cancer cells in metastatic sites

7 April 2017

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Reconstitution of actin-based motility of Listeria and Shigella using pure proteins

7 April 2017

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N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases

7 April 2017

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Foot and mouth: podosomes, invadopodia and circular dorsal ruffles

7 April 2017

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Phospholipase C and cofilin are required for carcinoma cell directionality in response to EGF stimulation

28 September 2017

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Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex

28 September 2017

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Regulation of actin dynamics by WASP and WAVE family proteins.

28 September 2017

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Cofilin promotes actin polymerization and defines the direction of cell motility

28 September 2017

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Signalling to actin assembly via the WASP (Wiskott-Aldrich syndrome protein)-family proteins and the Arp2/3 complex

28 September 2017

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The role of dynamin in the assembly and function of podosomes and invadopodia

28 September 2017

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The epidermal growth factor receptor tyrosine kinase inhibitor ZD1839 (Iressa) suppresses c-Src and Pak1 pathways and invasiveness of human cancer cells

28 September 2017

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Measurement of barbed ends, actin polymerization, and motility in live carcinoma cells after growth factor stimulation

28 September 2017

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Involvement of Cdc42 and Rac small G proteins in invadopodia formation of RPMI7951 cells

28 September 2017

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Intravital imaging of cell movement in tumours

28 September 2017

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Regulation of actin dynamics by WASP family proteins

28 September 2017

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Actin can reorganize into podosomes in aortic endothelial cells, a process controlled by Cdc42 and RhoA.

28 September 2017

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Podosomes: adhesion hot-spots of invasive cells

28 September 2017

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Macrophage podosomes assemble at the leading lamella by growth and fragmentation

28 September 2017

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Dynamin participates in focal extracellular matrix degradation by invasive cells

28 September 2017

1 reference

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Selective inhibition of the epidermal growth factor receptor by ZD1839 decreases the growth and invasion of ovarian clear cell adenocarcinoma cells.

28 September 2017

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Genome-wide screening of genes showing altered expression in liver metastases of human colorectal cancers by cDNA microarray

28 September 2017

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EGFR and cancer prognosis

28 September 2017

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N-WASP deficiency reveals distinct pathways for cell surface projections and microbial actin-based motility

28 September 2017

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How is actin polymerization nucleated in vivo?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171731

A functional link between dynamin and the actin cytoskeleton at podosomes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171731

A critical step in metastasis: in vivo analysis of intravasation at the primary tumor

28 September 2017

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Role of cofilin in epidermal growth factor-stimulated actin polymerization and lamellipod protrusion

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171731

Control of actin dynamics in cell motility. Role of ADF/cofilin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171731

Specialized surface protrusions of invasive cells, invadopodia and lamellipodia, have differential MT1-MMP, MMP-2, and TIMP-2 localization

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2171731

Proteolytic activity of specialized surface protrusions formed at rosette contact sites of transformed cells

28 September 2017

1 reference

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EGF stimulates lamellipod extension in metastatic mammary adenocarcinoma cells by an actin-dependent mechanism

28 September 2017

1 reference

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Imaging sites of N-wasp activity in lamellipodia and invadopodia of carcinoma cells.

28 September 2017

1 reference

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Podosome formation in cultured A7r5 vascular smooth muscle cells requires Arp2/3-dependent de-novo actin polymerization at discrete microdomains.

30 May 2018

1 reference

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Identification and testing of a gene expression signature of invasive carcinoma cells within primary mammary tumors.

30 May 2018

1 reference

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Differential Roles of WAVE1 and WAVE2 in Dorsal and Peripheral Ruffle Formation for Fibroblast Cell Migration

28 November 2018

1 reference

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Regulation of protrusion shape and adhesion to the substratum during chemotactic responses of mammalian carcinoma cells.

28 November 2018

1 reference

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28 November 2018

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28 November 2018

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Identifiers

DOI

10.1083/JCB.200407076

1 reference

release_gkkkgpmhwbf5tp5rkwcc2nrhqy

1817311

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/gkkkgpmhwbf5tp5rkwcc2nrhqy

24 November 2022

mapped directly with Wikidata item

1817311

1 reference

1 reference

1 reference