A central role for DOCK2 during interstitial lymphocyte motility and sphingosine-1-phosphate-mediated egress (Q24679761)

César Nombela-Arrieta

1

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Yoshinori Fukui

Yoshinori Fukui

8

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Matthias P Wymann

Matthias P Wymann

5

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Emilio Hirsch

Emilio Hirsch

6

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author name string

Thorsten R Mempel

2

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Silvia F Soriano

3

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Irina Mazo

4

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Carlos Martínez-A

7

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Jens V Stein

Journal of Experimental Medicine

10

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language of work or name

English

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publication date

19 March 2007

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published in

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volume

204

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issue

3

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page(s)

497-510

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cites work

Antigen-engaged B cells undergo chemotaxis toward the T zone and form motile conjugates with helper T cells

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Unconventional Rac-GEF activity is mediated through the Dock180-ELMO complex

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Rho GTPases in cell biology

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Sphingosine kinase 2 is required for modulation of lymphocyte traffic by FTY720

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

T-cell priming by dendritic cells in lymph nodes occurs in three distinct phases

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Identification of an evolutionarily conserved superfamily of DOCK180-related proteins with guanine nucleotide exchange activity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Haematopoietic cell-specific CDM family protein DOCK2 is essential for lymphocyte migration

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

A chemokine-driven positive feedback loop organizes lymphoid follicles

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

A putative chemokine receptor, BLR1, directs B cell migration to defined lymphoid organs and specific anatomic compartments of the spleen

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Expression of the sphingosine 1-phosphate receptor, S1P1, on T-cells controls thymic emigration

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

DOCK2 is essential for antigen-induced translocation of TCR and lipid rafts, but not PKC-theta and LFA-1, in T cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

CCR7 coordinates the primary immune response by establishing functional microenvironments in secondary lymphoid organs

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Stromal cell networks regulate lymphocyte entry, migration, and territoriality in lymph nodes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Lymphocyte egress from thymus and peripheral lymphoid organs is dependent on S1P receptor 1

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Sphingosine-1-phosphate: an enigmatic signalling lipid

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Two-photon imaging of lymphocyte motility and antigen response in intact lymph node

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Alteration of lymphocyte trafficking by sphingosine-1-phosphate receptor agonists

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Enhancement of capillary leakage and restoration of lymphocyte egress by a chiral S1P1 antagonist in vivo.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

CD69 acts downstream of interferon-alpha/beta to inhibit S1P1 and lymphocyte egress from lymphoid organs

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Chemokine control of lymphocyte trafficking: a general overview.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

S1P1-selective in vivo-active agonists from high-throughput screening: off-the-shelf chemical probes of receptor interactions, signaling, and fate

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

The S1P-analog FTY720 differentially modulates T-cell homing via HEV: T-cell-expressed S1P1 amplifies integrin activation in peripheral lymph nodes but not in Peyer patches.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Chemokines, sphingosine-1-phosphate, and cell migration in secondary lymphoid organs

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Cyclical modulation of sphingosine-1-phosphate receptor 1 surface expression during lymphocyte recirculation and relationship to lymphoid organ transit

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Dynamic behavior of T cells and thymocytes in lymphoid organs as revealed by two-photon microscopy.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Illuminating the landscape of in vivo immunity: insights from dynamic in situ imaging of secondary lymphoid tissues

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Intravital microscopy: visualizing immunity in context

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Stop and go traffic to tune T cell responses

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Do phosphoinositide 3-kinases direct lymphocyte navigation?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

CXCL12 mediates CCR7-independent homing of central memory cells, but not naive T cells, in peripheral lymph nodes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Homing and cellular traffic in lymph nodes

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Egress: a receptor-regulated step in lymphocyte trafficking

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

A stochastic view of lymphocyte motility and trafficking within the lymph node

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

From rafts to crafts: membrane asymmetry in moving cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

The CDM protein DOCK2 in lymphocyte migration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Sphingosine 1-phosphate, a key cell signaling molecule

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

The immune modulator FTY720 targets sphingosine 1-phosphate receptors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Neutrophils lacking phosphoinositide 3-kinase gamma show loss of directionality during N-formyl-Met-Leu-Phe-induced chemotaxis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

Coexpression of the chemokines ELC and SLC by T zone stromal cells and deletion of the ELC gene in the plt/plt mouse

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

The CC chemokine thymus-derived chemotactic agent 4 (TCA-4, secondary lymphoid tissue chemokine, 6Ckine, exodus-2) triggers lymphocyte function-associated antigen 1-mediated arrest of rolling T lymphocytes in peripheral lymph node high endothelial v

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

DOCK2 regulates chemokine-triggered lateral lymphocyte motility but not transendothelial migration

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2137902

CC chemokine ligand 19 secreted by mature dendritic cells increases naive T cell scanning behavior and their response to rare cognate antigen.

30 May 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20061780

Homeostatic lymphoid chemokines synergize with adhesion ligands to trigger T and B lymphocyte chemokinesis

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20061780

Rgs1 and Gnai2 regulate the entrance of B lymphocytes into lymph nodes and B cell motility within lymph node follicles.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20061780

The immunosuppressant FTY720 down-regulates sphingosine 1-phosphate G-protein-coupled receptors

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20061780

Differential requirements for DOCK2 and phosphoinositide-3-kinase gamma during T and B lymphocyte homing

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20061780

Cutting edge: differential roles for phosphoinositide 3-kinases, p110gamma and p110delta, in lymphocyte chemotaxis and homing

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20061780

Activation-regulated expression and chemotactic function of sphingosine 1-phosphate receptors in mouse splenic T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20061780

Sphingosine 1-phosphate type 1 receptor agonism inhibits transendothelial migration of medullary T cells to lymphatic sinuses

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20061780

Directional sensing requires G beta gamma-mediated PAK1 and PIX alpha-dependent activation of Cdc42.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20061780

Chemokines enhance immunity by guiding naive CD8+ T cells to sites of CD4+ T cell-dendritic cell interaction.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20061780

The T cell chemokine receptor CCR7 is internalized on stimulation with ELC, but not with SLC.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20061780

Thromboxane A2 modulates interaction of dendritic cells and T cells and regulates acquired immunity

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20061780

Sphingosine kinase type 2 is essential for lymphopenia induced by the immunomodulatory drug FTY720.

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20061780

Sphingosine-1-phosphate agonists increase macrophage homing, lymphocyte contacts, and endothelial junctional complex formation in murine lymph nodes

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20061780

Lymphocyte sequestration through S1P lyase inhibition and disruption of S1P gradients

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20061780

The immune modulator FTY720 inhibits sphingosine-1-phosphate lyase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20061780

Cutting edge: suppression of T cell chemotaxis by sphingosine 1-phosphate

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20061780

Deletion of DOCK2, a regulator of the actin cytoskeleton in lymphocytes, suppresses cardiac allograft rejection

21 January 2018

1 reference

https://api.crossref.org/works/10.1084%2FJEM.20061780

Genetic defect in T lymphocyte-specific homing into peripheral lymph nodes

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17325199

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Cutting edge: the B cell chemokine CXC chemokine ligand 13/B lymphocyte chemoattractant is expressed in the high endothelial venules of lymph nodes and Peyer's patches and affects B cell trafficking across high endothelial venules

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17325199

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

The Rap GTPases mediate CXCL13- and sphingosine1-phosphate-induced chemotaxis, adhesion, and Pyk2 tyrosine phosphorylation in B lymphocytes

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17325199

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1084/JEM.20061780

1 reference

1 reference

1 reference

PubMed publication ID

17325199

1 reference